Radiation-induced lung injury: Difference between revisions
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| name = Radiation-induced lung injury |
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| image = Radiation pneumonitis (4863802675).jpg |
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| caption = Radiation pneumonitis |
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'''Radiation-induced lung injury''' is a general term for damage to the [[lung]]s |
'''Radiation-induced lung injury''' ('''RILI''') is a general term for damage to the [[lung]]s as a result of exposure to [[ionizing radiation]].<ref>{{Cite journal|last1=Marks|first1=Lawrence B.|last2=Yu|first2=Xiaoli|last3=Vujaskovic|first3=Zjelko|last4=Small|first4=William|last5=Folz|first5=Rodney|last6=Anscher|first6=Mitchell S.|date=July 2003|title=Radiation-induced lung injury|journal=Seminars in Radiation Oncology|volume=13|issue=3|pages=333–345|doi=10.1016/S1053-4296(03)00034-1|issn=1053-4296|pmid=12903021}}{{Subscription or libraries|sentence|via=[[ScienceDirect]]}}</ref> In general terms, such damage is divided into early [[Inflammation|inflammatory]] damage (''radiation pneumonitis'') and later complications of chronic [[scarring]] (''radiation fibrosis''). Pulmonary radiation injury most commonly occurs as a result of [[radiation therapy]] administered to treat [[cancer]].{{citation needed|date=November 2017}} |
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==Symptoms and signs== |
==Symptoms and signs== |
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The [[lung]]s are a radiosensitive organ, and radiation [[pneumonitis]] can occur leading to [[pulmonary insufficiency]] and death (100% after exposure to 50 gray of radiation), in a few months.Radiation [[pneumonitis]] is characterized by: |
The [[lung]]s are a radiosensitive organ, and radiation [[pneumonitis]] can occur leading to [[pulmonary insufficiency]] and death (100% after exposure to 50 gray of radiation), in a few months. Radiation [[pneumonitis]] is characterized by: |
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*Loss of [[epithelial cell]]s |
*Loss of [[epithelial cell]]s |
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*[[Edema]] |
*[[Pulmonary edema|Edema]] |
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*[[Inflammation]] |
*[[Inflammation]] |
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*Occlusions airways, air sacs and blood vessels |
*Occlusions airways, air sacs and blood vessels |
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*[[Fibrosis]] |
*[[Fibrosis]] |
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Symptoms of radiation pneumonitis include: [[fever]], [[cough]], chest congestion, [[shortness of breath]], chest pain |
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==Cause== |
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{{Empty section}} |
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==Mechanism== |
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==Diagnosis== |
==Diagnosis== |
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{{Empty section}} |
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High resolution CT thorax |
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==Treatment== |
==Treatment== |
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{{Empty section}} |
{{Empty section|date=November 2017}} |
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“The Canadian Cancer society mentions these things that help to manage radiation, |
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Your healthcare team may recommend medicines to treat radiation pneumonitis, such as: |
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decongestants |
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cough suppressants |
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bronchodilators |
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corticosteroids to reduce inflammation |
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oxygen therapy |
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You can also try the following to help manage symptoms: |
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Rest if you feel short of breath. |
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Drink more fluids and use a cool-air vaporizer or humidifier to keep the air moist. |
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Use an extra pillow to raise your head and upper body while resting or sleeping. |
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Avoid the outdoors on hot, humid days or very cold days (which can irritate the lungs). |
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Wear light, loose-fitting tops and avoid anything tight around the neck, such as ties or shirt collars.“<ref>{{cite web | url=https://www.cancer.ca/en/cancer-information/diagnosis-and-treatment/managing-side-effects/radiation-pneumonitis/?region=qc | title=Radiation pneumonitis | date=November 2023 }}</ref> |
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For more information go to their website, as they have accurate information.[https://www.cancer.ca/en/cancer-information/diagnosis-and-treatment/managing-side-effects/radiation-pneumonitis/?region=qc “More Info”] |
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==See also== |
==See also== |
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*[[ |
*[[Radiation poisoning]] |
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== References == |
== References == |
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{{reflist}} |
{{reflist}} |
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==Further reading== |
==Further reading== |
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*{{cite web|last1=Radiation |
*{{cite web|last1=Radiation Emergency Medical Management|title=Time Phases of Acute Radiation Syndrome - Radiation Emergency Medical Management|url=https://www.remm.nlm.gov/ars_timephases1.htm|website=www.remm.nlm.gov|publisher=U.S. Department of Health and Human Services|accessdate=7 November 2017|language=en}} |
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==External links== |
== External links == |
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{{Medical resources |
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| DiseasesDB = |
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| ICD10 = {{ICD10|J|70|0|j|60}}-{{ICD10|J|70|1|j|60}} |
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| ICD9 = {{ICD9|508.0}}-{{ICD9|508.1}} |
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| ICDO = |
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| OMIM = |
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| MedlinePlus = |
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| eMedicineSubj = |
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| eMedicineTopic = |
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| MeshID = D017564 |
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}} |
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*[https://www.ncbi.nlm.nih.gov/pubmed/ PubMed] |
*[https://www.ncbi.nlm.nih.gov/pubmed/ PubMed] |
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{{Respiratory pathology}} |
{{Respiratory pathology}} |
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Latest revision as of 16:08, 6 April 2024
| Radiation-induced lung injury | |
|---|---|
.jpg) | |
| Radiation pneumonitis | |
| Specialty | Pulmonology  |
Radiation-induced lung injury (RILI) is a general term for damage to the lungs as a result of exposure to ionizing radiation.[1] In general terms, such damage is divided into early inflammatory damage (radiation pneumonitis) and later complications of chronic scarring (radiation fibrosis). Pulmonary radiation injury most commonly occurs as a result of radiation therapy administered to treat cancer.[citation needed]
Symptoms and signs
[edit]The lungs are a radiosensitive organ, and radiation pneumonitis can occur leading to pulmonary insufficiency and death (100% after exposure to 50 gray of radiation), in a few months. Radiation pneumonitis is characterized by:
- Loss of epithelial cells
- Edema
- Inflammation
- Occlusions airways, air sacs and blood vessels
- Fibrosis
Symptoms of radiation pneumonitis include: fever, cough, chest congestion, shortness of breath, chest pain
Diagnosis
[edit]High resolution CT thorax
Treatment
[edit]![[icon]](/https/en.wikipedia.org/wiki/File:Wiki_letter_w_cropped.svg){kind=small} | This section is empty. You can help by adding to it. (November 2017) |
“The Canadian Cancer society mentions these things that help to manage radiation,
Your healthcare team may recommend medicines to treat radiation pneumonitis, such as:
decongestants cough suppressants bronchodilators corticosteroids to reduce inflammation oxygen therapy You can also try the following to help manage symptoms:
Rest if you feel short of breath. Drink more fluids and use a cool-air vaporizer or humidifier to keep the air moist. Use an extra pillow to raise your head and upper body while resting or sleeping. Avoid the outdoors on hot, humid days or very cold days (which can irritate the lungs). Wear light, loose-fitting tops and avoid anything tight around the neck, such as ties or shirt collars.“[2]
For more information go to their website, as they have accurate information.“More Info”
See also
[edit]References
[edit]- ^ Marks, Lawrence B.; Yu, Xiaoli; Vujaskovic, Zjelko; Small, William; Folz, Rodney; Anscher, Mitchell S. (July 2003). "Radiation-induced lung injury". Seminars in Radiation Oncology. 13 (3): 333–345. doi:10.1016/S1053-4296(03)00034-1. ISSN 1053-4296. PMID 12903021. – via ScienceDirect (Subscription may be required or content may be available in libraries.)
- ^ "Radiation pneumonitis". November 2023.
Further reading
[edit]- Radiation Emergency Medical Management. "Time Phases of Acute Radiation Syndrome - Radiation Emergency Medical Management". www.remm.nlm.gov. U.S. Department of Health and Human Services. Retrieved 7 November 2017.