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Electron therapy

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Electron therapy
ICD-992.25

Electron therapy or electron beam therapy (EBT) is a kind of external beam radiotherapy where electrons are directed to a tumor site.

Equipment

Electron beam therapy is performed using a medical linear accelerator. The same device can also be used to produce high energy photon beams. When electrons are required, the x-ray target is retracted out of the beam and the electron beam is collimated with a piece of apparatus known as an applicator or an additional collimating insert, constructed from a low melting point alloy.

Properties

Note the rapid falloff for 4 MeV electron compared to X rays.

Electron beams have a finite range, after which dose falls off rapidly. Therefore, they spare deeper healthy tissue. The depth of the treatment is selected by the appropriate energy. Unlike photon beams there is no surface sparing effect, so electron therapy is used when the target extends to the patient's skin.

Indications

Electron beam therapy is used in the treatment of superficial tumors like cancer of skin regions, or total skin (e.g. mycosis fungoides), diseases of the limbs (e.g. melanoma and lymphoma), nodal irradiation, and it may also be used to boost the radiation dose to the surgical bed after mastectomy or lumpectomy. For deeper regions intraoperative electron radiation therapy might be applied.

Total skin electron therapy

Total skin electron therapy (TSET) is a common treatment for mycosis fungoides and Sézary syndrome, the two most common forms of cutaneous T cell lymphoma. The treatment involves using very broad electron beams to deliver radiation to the entire skin surface. Typically this is done using six dual-beams: First, the upper portion of the patient is irradiated with one beam and then the lower portion is irradiated. Then the patient rotates one-sixth of a turn and is treated with the second dual-beam. This process is repeated until the patient has been irradiated from six directions each with an upper and lower electron beam.[1]

Since the 1950s the “Stanford technique” of total skin electron radiation has been developed. In the updated “Stanford technique” the patient stands about 10 meters from a radiation source, with a large acrylic sheet in between to scatter the electrons across a broad area. Then the patient carefully assumes six different positions.[2]

See also

References

  1. ^ Karzmark, C. J. (1987). "AAPM Report No. 23 Total Skin Electron Therapy: Technique and Dosimetry". {{cite journal}}: Cite journal requires |journal= (help)
  2. ^ Williams SC (2015). "The rarest of rashes". Stanford Medicine.
  • Eric E. Klein: "Electron-Beam Therapy: Dosimetry, Planning, and Techniques" in: Edward C. Halperin, Carlos A. Perez, Luther W. Brady (ed.): Perez and Brady's Principles and Practice of Radiation Oncology, 5th. edition, 2008