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H2BFWT

From Wikipedia, the free encyclopedia
(Redirected from H2BW1)
H2BW1
Identifiers
AliasesH2BW1, H2B histone family member W, testis specific, H2BFWT, H2B.W histone 1, TH2B-175
External IDsOMIM: 300507; HomoloGene: 128214; GeneCards: H2BW1; OMA:H2BW1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001002916

n/a

RefSeq (protein)

NP_001002916

n/a

Location (UCSC)Chr X: 104.01 – 104.01 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

H2B histone family, member W, testis-specific is a protein that in humans is encoded by the H2BFWT gene.[3]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.[provided by RefSeq, Jan 2010].[3]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000123569Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: H2B histone family, member W, testis-specific". Retrieved 2012-03-12.

Further reading

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