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Ashwagandha side effects

Ashwagandha side effects

Navin Khosla NowPatientGreen tick
Created on 11 Aug 2024
Updated on 11 Aug 2024

Ashwagandha (Withania somnifera) is an ancient Ayurvedic herb, used in traditional Indian medicine (Ayurveda). Many people take ashwagandha to reduce stress, improve sleep quality, and even boost fertility, capturing the attention of health-conscious individuals worldwide. However, as with any supplement, it’s important to understand the potential risks and side effects associated with ashwagandha before incorporating it into one’s daily routine.

In this article, we’ll look into the latest research and information to uncover the potential drawbacks of this adaptogenic (a substance that can boost immunity and help the body respond to stress by decreasing cortisol levels) herb. From gastrointestinal disturbances to possible interactions with certain medications, we will look into understanding Ashwagandha’s safety profile. By the end of this article, you’ll know whether this herbal supplement is right for you.

What is ashwagandha?

Ashwagandha, also known as “Indian Ginseng” or “Winter Cherry,” is a remarkable evergreen shrub that has been used in traditional Ayurvedic medicine in India and Africa for centuries. Its impressive array of bioactive compounds, including a group of substances called withanolides, have been linked to a wide range of potential health benefits. From reducing inflammation and blood sugar levels, increasing antioxidant activity and boosting immunity, to improving cognitive function.

However, as with any powerful natural remedy, ashwagandha also comes with its fair share of potential risks and side effects. As we delve deeper into the research, it becomes clear that while this traditional medicine may offer significant benefits, it’s important to approach its use with caution and a thorough understanding of its potential drawbacks.

Gastrointestinal disturbances

One of the most commonly reported side effects of ashwagandha is gastrointestinal discomfort. Studies have shown that a significant number of individuals who incorporate ashwagandha into their supplementation routine may experience issues such as stomach upset, loose bowel movements, diarrhoea, and even nausea.

The root cause of these digestive woes is not entirely clear, but it’s believed to be linked to the complex chemical composition of the herb. Ashwagandha contains a variety of compounds, some of which may not sit well with certain individuals’ gut microbiomes or digestive systems. Additionally, the quality and purity of the ashwagandha supplement itself may play a role in the likelihood of experiencing these unpleasant side effects.

Thyroid concerns

One of the more concerning potential side effects of ashwagandha is its impact on thyroid function. The herb has been shown to have the ability to increase the conversion of the less potent thyroid hormone, T4, to the more active form, T3. This can be particularly problematic for individuals with pre-existing thyroid conditions, as it may lead to a state of hyperthyroidism, characterised by an overactive thyroid gland.

Experts strongly advise those with any kind of thyroid disorder, whether it’s hypothyroidism or hyperthyroidism, to exercise caution when considering ashwagandha supplementation. It’s crucial to consult with a healthcare provider before incorporating this herb into one’s wellness routine, as the potential consequences can be quite serious.

Autoimmune complications

Another area of concern when it comes to ashwagandha’s side effects is its potential impact on the immune system. Some research has suggested that the herb may have the ability to modulate the body’s immune response, which can be problematic for individuals with autoimmune conditions.

Autoimmune disorders, such as rheumatoid arthritis, lupus, and multiple sclerosis, are characterised by the immune system’s misguided attack on the body’s healthy tissues. In these cases, ashwagandha’s properties may worsen the underlying condition.

Individuals with any known autoimmune disorders are strongly advised to steer clear of ashwagandha supplementation unless explicitly approved and monitored by their healthcare provider. The potential risks simply outweigh the potential benefits in these cases.

Pregnancy and breastfeeding concerns

The herb’s potential effects on fetal development and infant health are not yet fully understood, and the available research is limited.

Experts generally recommend that pregnant women and those who are breastfeeding avoid ashwagandha altogether, as the the long-term safety of ashwagandha is not known. The potential complications, such as miscarriage or developmental issues in the child, are simply too great to justify the use of this supplement during these critical stages of life.

Surgical risks

Individuals who are scheduled to undergo surgery or have recently undergone a medical procedure are also advised to steer clear of ashwagandha supplementation. The herb’s potential to interact with anaesthesia, as well as its ability to affect blood clotting and wound healing, can pose significant risks in the perioperative period.

Healthcare providers often recommend that patients discontinue the use of ashwagandha and other herbal supplements several weeks before a scheduled surgery. This allows the body to clear the compounds and minimise the likelihood of adverse interactions or complications during the surgical process.

Ashwagandha and medication interactions

One of the most significant concerns when it comes to ashwagandha is its potential to interact with a wide range of medications. From diabetes and high blood pressure medications to immunosuppressants, sedatives, and thyroid hormone treatments, the list of potential interactions is extensive.

These interactions can lead to a variety of issues, such as decreased or increased effectiveness of the medications, drowsiness, amplified side effects, or even the development of dangerous medical conditions. Individuals taking any prescription or over-the-counter drugs are strongly advised to consult with their healthcare provider before adding ashwagandha to their regimen.

Liver injury

While rare, there have been several reported cases linking the use of ashwagandha supplements to liver injury. The exact mechanisms behind this potential side effect are not yet fully understood, but it’s believed to be related to the herb’s complex chemical composition and the quality of the supplements themselves.

Individuals who experience any signs of liver problems such as abdominal pain, nausea, vomiting, or jaundice, should discontinue ashwagandha use immediately and seek medical attention. Liver injury can be a serious and potentially life-threatening condition, and it’s not something to be taken lightly.

Hormone-sensitive cancers

Another area of concern when it comes to ashwagandha is its potential impact on hormone-sensitive cancers, particularly prostate cancer. The herb has been shown to have the ability to increase testosterone levels, which can be problematic for individuals with certain types of prostate cancer that are fueled by this hormone.

Experts caution that individuals with a history of hormone-sensitive cancers, such as prostate, breast, or ovarian cancer, should avoid ashwagandha supplementation altogether. The risks of exacerbating the condition or promoting cancer growth simply outweigh any potential benefits.

Ashwagandha and long-term safety

While the short-term use of ashwagandha is generally considered safe for most individuals, the long-term safety of this herb is still a subject of ongoing research and debate. The lack of robust studies on the effects of prolonged ashwagandha supplementation leaves many unanswered questions.

Concerns have been raised about the potential for cumulative effects, potential organ damage, or the development of chronic conditions as a result of long-term ashwagandha use. Until more definitive research is available, individuals must exercise caution and closely monitor their health when incorporating this herb into their daily routine.

Ashwagandha supplements

One final consideration when it comes to ashwagandha side effects is the quality and purity of the supplements available on the market. As with any dietary supplement, the lack of rigorous oversight and regulation in the industry can lead to a wide variation in the composition and potency of ashwagandha products.

Consumers are advised to exercise caution when selecting ashwagandha supplements, opting for brands that have been independently tested and verified by reputable third-party organisations. Additionally, it’s crucial to follow dosage recommendations carefully and to discontinue use if any adverse effects are experienced.

Dosage considerations

Determining the appropriate dosage of ashwagandha is crucial to minimising the risk of side effects. The recommended dosage typically ranges from 500 to 1,000 milligrams per day, split into two doses. However, it’s essential to note that there is no standard dose of ashwagandha, it may vary depending on the individual, the specific ashwagandha preparation being used, and the intended purpose of the supplement.

Consulting with healthcare providers

Before incorporating ashwagandha into your wellness routine, it’s essential to consult with your healthcare provider, especially if you have any underlying health conditions or are taking any medications. Your healthcare provider can assess your individual needs, provide medical advice on safe dosages, and help you navigate any potential interactions or contraindications.

Conclusion: Balancing the risks and benefits of ashwagandha

Ashwagandha is a remarkable herb with a long history of traditional use and a growing body of scientific evidence supporting its potential health benefits. However, as this comprehensive exploration has revealed, it’s crucial to approach this supplement with a clear understanding of its potential risks and side effects.

From gastrointestinal disturbances and thyroid concerns to autoimmune complications and medication interactions, the list of ashwagandha’s potential drawbacks is not to be taken lightly. Individuals with pre-existing medical conditions, those taking medications, and those who are pregnant or breastfeeding should exercise extreme caution and consult with their healthcare providers before incorporating this herb into their wellness routines.

Key takeaways

  • Ashwagandha’s complex chemical composition, including withanolides, can lead to a range of potential side effects
  • Common side effects include gastrointestinal distress, thyroid complications, autoimmune disorder exacerbation, and liver injury
  • Pregnant and breastfeeding women, as well as those with hormone-sensitive prostate cancer, should avoid ashwagandha
  • Ashwagandha may interact with various medications, including those for diabetes, high blood pressure, seizures, and immunosuppression
  • Recommended dosages typically range from 500 to 1,000 milligrams per day, split into two doses
  • Quality and purity of ashwagandha supplements are crucial, as third-party certifications can help ensure safety and efficacy
  • Consulting with a healthcare provider is essential before incorporating ashwagandha into your wellness routine

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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