Synthetic cathinone abuse

Clin Pharmacol. 2013 Jul 2:5:109-15. doi: 10.2147/CPAA.S42832. Print 2013.

Abstract

The abuse of synthetic cathinones, widely known as bath salts, has been increasing since the mid-2000s. These substances are derivatives of the naturally occurring compound cathinone, which is the primary psychoactive component of khat. The toxicity of synthetic cathinones includes significant sympathomimetic effects, as well as psychosis, agitation, aggression, and sometimes violent and bizarre behavior. Mephedrone and methylenedioxypyrovalerone are currently the predominantly abused synthetic cathinones.

Keywords: alkaloids/poisoning; designer drugs/chemistry; street drugs/pharmacology; substance-related disorders/epidemiology.