The devil is in the details: incomplete reporting in preclinical animal research

MT Avey, D Moher, KJ Sullivan, D Fergusson… - PLoS …, 2016 - journals.plos.org
Incomplete reporting of study methods and results has become a focal point for failures in
the reproducibility and translation of findings from preclinical research. Here we demonstrate …

Accelerating biomedical discoveries through rigor and transparency

JA Hewitt, LL Brown, SJ Murphy, F Grieder… - ILAR …, 2017 - academic.oup.com
Difficulties in reproducing published research findings have garnered a lot of press in recent
years. As a funder of biomedical research, the National Institutes of Health (NIH) has taken …

Sloppy reporting on animal studies proves hard to change

M Enserink - 2017 - science.org
Sloppy reporting on animal studies proves hard to change | Science news careers commentary
Journals Science Science brought to you byGoogle Indexer Log in science science advances …

Two years later: journals are not yet enforcing the ARRIVE guidelines on reporting standards for pre-clinical animal studies

D Baker, K Lidster, A Sottomayor, S Amor - PLoS biology, 2014 - journals.plos.org
There is growing concern that poor experimental design and lack of transparent reporting
contribute to the frequent failure of pre-clinical animal studies to translate into treatments for …

[PDF][PDF] The ARRIVE guidelines animal research: reporting in vivo experiments

C Kilkenny, WJ Browne, IC Cuthill, M Emerson… - PLoS Biol, 2010 - research.fsu.edu
Background 3 a. Include sufficient scientific background (including relevant references to
previous work) to understand the motivation and context for the study, and explain the …

The Researchers' View of Scientific Rigor—Survey on the Conduct and Reporting of In Vivo Research

TS Reichlin, L Vogt, H Würbel - PloS one, 2016 - journals.plos.org
Reproducibility in animal research is alarmingly low, and a lack of scientific rigor has been
proposed as a major cause. Systematic reviews found low reporting rates of measures …

Reproducible preclinical research—Is embracing variability the answer?

NA Karp - PLoS biology, 2018 - journals.plos.org
Translational failures and replication issues of published research are undermining
preclinical research and, if the outcomes are questionable, raise ethical implications over …

[HTML][HTML] Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

NP Du Sert, A Ahluwalia, S Alam, MT Avey… - PLoS …, 2020 - journals.plos.org
Improving the reproducibility of biomedical research is a major challenge. Transparent and
accurate reporting is vital to this process; it allows readers to assess the reliability of the …

A checklist is associated with increased quality of reporting preclinical biomedical research: a systematic review

SH Han, TF Olonisakin, JP Pribis, J Zupetic, JH Yoon… - PloS one, 2017 - journals.plos.org
Irreproducibility of preclinical biomedical research has gained recent attention. It is
suggested that requiring authors to complete a checklist at the time of manuscript …

Twelve years after the ARRIVE guidelines: Animal research has not yet arrived at high standards

J Song, M Solmi, AF Carvalho, JI Shin… - Laboratory …, 2024 - journals.sagepub.com
The reproducibility crisis across animal studies jeopardizes the credibility of the main
findings derived from animal research, even though these findings are critical for informing …