The devil is in the details: incomplete reporting in preclinical animal research
Incomplete reporting of study methods and results has become a focal point for failures in
the reproducibility and translation of findings from preclinical research. Here we demonstrate …
the reproducibility and translation of findings from preclinical research. Here we demonstrate …
Accelerating biomedical discoveries through rigor and transparency
JA Hewitt, LL Brown, SJ Murphy, F Grieder… - ILAR …, 2017 - academic.oup.com
Difficulties in reproducing published research findings have garnered a lot of press in recent
years. As a funder of biomedical research, the National Institutes of Health (NIH) has taken …
years. As a funder of biomedical research, the National Institutes of Health (NIH) has taken …
Sloppy reporting on animal studies proves hard to change
M Enserink - 2017 - science.org
Sloppy reporting on animal studies proves hard to change | Science news careers commentary
Journals Science Science brought to you byGoogle Indexer Log in science science advances …
Journals Science Science brought to you byGoogle Indexer Log in science science advances …
Two years later: journals are not yet enforcing the ARRIVE guidelines on reporting standards for pre-clinical animal studies
D Baker, K Lidster, A Sottomayor, S Amor - PLoS biology, 2014 - journals.plos.org
There is growing concern that poor experimental design and lack of transparent reporting
contribute to the frequent failure of pre-clinical animal studies to translate into treatments for …
contribute to the frequent failure of pre-clinical animal studies to translate into treatments for …
[PDF][PDF] The ARRIVE guidelines animal research: reporting in vivo experiments
Background 3 a. Include sufficient scientific background (including relevant references to
previous work) to understand the motivation and context for the study, and explain the …
previous work) to understand the motivation and context for the study, and explain the …
The Researchers' View of Scientific Rigor—Survey on the Conduct and Reporting of In Vivo Research
TS Reichlin, L Vogt, H Würbel - PloS one, 2016 - journals.plos.org
Reproducibility in animal research is alarmingly low, and a lack of scientific rigor has been
proposed as a major cause. Systematic reviews found low reporting rates of measures …
proposed as a major cause. Systematic reviews found low reporting rates of measures …
Reproducible preclinical research—Is embracing variability the answer?
NA Karp - PLoS biology, 2018 - journals.plos.org
Translational failures and replication issues of published research are undermining
preclinical research and, if the outcomes are questionable, raise ethical implications over …
preclinical research and, if the outcomes are questionable, raise ethical implications over …
[HTML][HTML] Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
Improving the reproducibility of biomedical research is a major challenge. Transparent and
accurate reporting is vital to this process; it allows readers to assess the reliability of the …
accurate reporting is vital to this process; it allows readers to assess the reliability of the …
A checklist is associated with increased quality of reporting preclinical biomedical research: a systematic review
Irreproducibility of preclinical biomedical research has gained recent attention. It is
suggested that requiring authors to complete a checklist at the time of manuscript …
suggested that requiring authors to complete a checklist at the time of manuscript …
Twelve years after the ARRIVE guidelines: Animal research has not yet arrived at high standards
The reproducibility crisis across animal studies jeopardizes the credibility of the main
findings derived from animal research, even though these findings are critical for informing …
findings derived from animal research, even though these findings are critical for informing …