Per‐and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research

SE Fenton, A Ducatman, A Boobis… - Environmental …, 2021 - Wiley Online Library
Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …

Power failure: why small sample size undermines the reliability of neuroscience

KS Button, JPA Ioannidis, C Mokrysz… - Nature reviews …, 2013 - nature.com
A study with low statistical power has a reduced chance of detecting a true effect, but it is
less well appreciated that low power also reduces the likelihood that a statistically significant …

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

N Percie du Sert, V Hurst, A Ahluwalia… - Journal of Cerebral …, 2020 - journals.sagepub.com
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal
Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve …

[HTML][HTML] Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

NP Du Sert, A Ahluwalia, S Alam, MT Avey… - PLoS …, 2020 - journals.plos.org
Improving the reproducibility of biomedical research is a major challenge. Transparent and
accurate reporting is vital to this process; it allows readers to assess the reliability of the …

[HTML][HTML] ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020

E Lilley, SC Stanford, DE Kendall… - British journal of …, 2020 - ncbi.nlm.nih.gov
1. BACKGROUND The BJP has been and remains an active advocate of the ARRIVE
(Animal Research: Reporting of in vivo Experiments) guidelines (Kilkenny, Browne, Cuthill …

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

G Vlachogiannis, S Hedayat, A Vatsiou, Y Jamin… - Science, 2018 - science.org
Patient-derived organoids (PDOs) have recently emerged as robust preclinical models;
however, their potential to predict clinical outcomes in patients has remained unclear. We …

SYRCLE's risk of bias tool for animal studies

CR Hooijmans, MM Rovers, RBM De Vries… - BMC medical research …, 2014 - Springer
Abstract Background Systematic Reviews (SRs) of experimental animal studies are not yet
common practice, but awareness of the merits of conducting such SRs is steadily increasing …

[HTML][HTML] The world cancer research fund/American institute for cancer research third expert report on diet, nutrition, physical activity, and cancer: impact and future …

SK Clinton, EL Giovannucci, SD Hursting - The Journal of nutrition, 2020 - Elsevier
ABSTRACT The Third Expert Report on Diet, Nutrition, Physical Activity, and Cancer: A
Global Perspective by the World Cancer Research Fund (WCRF) and the American Institute …

Chemically induced mouse models of acute and chronic intestinal inflammation

S Wirtz, V Popp, M Kindermann, K Gerlach… - Nature protocols, 2017 - nature.com
Inflammatory bowel diseases (IBDs) result in diarrhea and abdominal pain with further
potential complications such as tissue fibrosis and stenosis. Animal models help in …

Sex and gender equity in research: rationale for the SAGER guidelines and recommended use

S Heidari, TF Babor, P De Castro, S Tort… - Research integrity and …, 2016 - Springer
Background Sex and gender differences are often overlooked in research design, study
implementation and scientific reporting, as well as in general science communication. This …