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Still to ARRIVE at adequate reporting of orthodontic studies involving animal models

D Flitti, N Pandis, J Seehra - European journal of orthodontics, 2024
… To facilitate clear and transparent reporting of animal studies the ARRIVE
guidelines were initially developed and introduced in 2010 [14] and subsequently
updated and superseded by the ARRIVE 2.0 guidelines in 2020 [15]. The original …

The OBSERVE guidelines provide refinement criteria for rodent oncology models

AC Ritter, C Cheleuitte-Nieves, NS Lipman - Nature Protocols, 2024
… The lack of reproducibility in in vivo studies is a considerable concern in
biomedical research 1 . … and ARRIVE guidelines, will enhance study design and
reporting, harmonize intra- and inter-study observations, improve animal welfare …

OBSERVE: guidelines for the refinement of rodent cancer models

SI De Vleeschauwer, M van de Ven, A Oudin… - Nature Protocols, 2024
… To maximize the likelihood of successful clinical translation, preclinical
biomedical studies require stringent design. This should include … guidance on
how to plan animal experiments, the ARRIVE guidelines mainly focus on the proper …

Investigation of Morphological Variations in Esme and Pırlak Sheep Raised in Breeder's Conditions

O KARACA, N ATA, K CANAZ, İ CEMAL, O YILMAZ
… The animal material used in this study consists of a total of 612 sheep, including
311 Eşme sheep from three breeders and … animal experiments (European Union,
2010), ARRIVE guidelines (Kilkenny et al., 2010) and national regulation on the …

Global Review on the 3Rs and Beyond for Animal Experimentation

S Dobhal, S Banerjee, MF Singh, VA Saharan - … of Research Methodology and Ethics …, 2024
Biomedical research in place of animal research can be a reliable alternative.
Adverse out‑ … The KSAAE was founded in the year 2010 to promote the
substitution of laboratory animalsARRIVE guidelines was to upgrade the …

CAF to the rescue! Potential and challenges of combination antifungal therapy for reducing morbidity and mortality in hospitalized patients with serious fungal …

S Jacobs, V Chaturvedi - medRxiv, 2024
studies for invasive candidiasis, cryptococcosis, invasive aspergillosis, and
mucormycosis. Additionally, we summarize findings from animal … Future CAF trials
should be prioritized according to animal models showing improved survival and …

Dysregulation of circadian clock gene expression patterns in a treatment‐resistant animal model of depression

K Højgaard, E Kaadt, BH Mumm, VS Pereira, B Elfving - Journal of Neurochemistry, 2024
… , most of the known animal models of depression have yet to be evaluated for
their eligibility to model CR disturbances. In this study, we investigate the potential of
adrenocorticotropic hormone (ACTH)‐treated animals as a disease model for …

Exploring dose–response variability and relative severity assessment in STZ-induced diabetes male NSG mice

SR Talbot, M Heider, M Wirth, A Jörns, O Naujok - Scientific Reports, 2024
… , particularly mice, play a unique and important role in behavioral and biomedical
research in basic and preclinical studies. Although many … Housing and
experimentation of laboratory animals in this study were conducted in accordance …

Treatment of vascular dementia in female rats with AV-001, an Angiopoietin-1 mimetic peptide, improves cognitive function

H Gao, X Liu, P Venkat, E Findeis, A Zacharek… - Frontiers in Neuroscience, 2024
… Therefore, this model was employed in the present study. We and other … We did
not examine the effect of AV-001 on cerebral blood vessels following MMI in the
present study. However, we have revealed that AV-001 [Vasculotide (VT)] treatment …

Chemical Composition of Two Grey Mullet Species (Chelon auratus, Mugil cephalus): A Comparative Study on Wild and Aquaculture-Adapted Species

EC Çankırılıgil, A Altuntaş - Çanakkale Onsekiz Mart University Journal of Marine …, 2024
… Throughout the adaptation and harvesting procedures, strict adherence to
ARRIVE guidelines (Kilkenny et al., 2010) and EU directive for animal experiments (…
All animal experiments were performed according to the ARRIVE guidelines and EU …
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