After several of Bailey's patients die, she becomes the focus of a CDC investigation; Cristina teases Alex about his feelings for Jo; Owen continues to take care of Ethan while his parents remain in the hospital.
Castle is captured and forced to work with strangers to solve deranged puzzles and mind games, while Beckett and the 12th Precinct race against time to rescue Castle and catch a killer.
Pete and Violet go to a marriage counselor; Amelia gets some devistating news; Mason refuses to speak to Charlotte and Cooper.
Mummified remains of a woman put the team's investigative skills to the test. Jane works from her hospital room as she - with the support of Maura and her family - seeks to recover from a devastating loss.
The team helps Korsak investigate an old case that has gone very, very cold. Jane refuses to believe that she's not ready to go back on duty and takes some untraditional steps to stay involved.