Confirm delete?

Menu Search Content
Bertin Bioreagent
logo
Recherche
All categories
Contact Us
You are here :

Spr-Characterized Antiganglioside Antibodies

SPR-characterized antiganglioside antibodies

Date : Since 21/08/2024

Place : Paris, France

Bioreagents

Biophysical characterization methods such as surface plasmon resonance (SPR) are powerful tools for characterizing molecular interactions and binding mechanisms, including antibody-antigen, protein-drug and protein-protein interactions.

 

 When used to analyze antibody-antigen interactions, SPR data can help scientists select antibodies with optimal characteristics for their specific applications. The equilibrium dissociation constant (KD), for example, can be used to assess antibody affinity and sensitivity.

Recently, Cayman scientists used the SPR method to characterize the binding kinetics and affinities of several of their anti-ganglioside monoclonal antibodies with their respective antigens using Biacore technologies:

 

Monoclonal Antibody

Clone

Antigene

KD

Reference

Ganglioside GD1a

MOG35

Ganglioside GD1a (bovine brain) (sodium salt)

2.01 μM

38295

Ganglioside GD1a

TBG3

Ganglioside GD1a (bovine brain) (sodium salt)

1.36 μM

38296

Ganglioside GD1b

MOG1

Ganglioside GD1b (porcine) (sodium salt)

0.052 μM

38293

Ganglioside GM1

DG2

Ganglioside GM1 (porcine brain) (sodium salt)

1.81 μM

38290

Ganglioside GQ1b

CGM3

Ganglioside GQ1b Mixture (sodium salt)

8.18 μM

38287

Discover the Cayman Catalog

All news & events
Top

My account

Connect or create an account

Copyright © Bertin Bioreagent - All rights reserved

Made by Eolas