Sarah Chalke was pregnant in real life in this season.
Neil Flynn (The Janitor) left the show to portray "Mike Heck" in "The Middle".
Judy Reyes (Carla) declined to do any guest spots in this season.
Christa Miller left the show to portray Ellie Torres in "Cougar Town" with Courteney Cox, who guest starred at the beginning of season 8.
Winston College is a homage to Scrubs producer Randall Winston (he also portrayed Leonard, the black security guard with a hook for a hand and a giant afro), as stated in Scrubs Season 9 DVD.