“Devon was a student in a lab that I taught. He had quite a high-level understanding of each experiment he was working on. His diligence and hard work made him a stellar student in my class.”
Devon Cayer
San Diego County, California, United States
4K followers
500+ connections
About
My entrepreneurial philosophies --
1. Always push the boundaries of what is…
Contributions
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How can you optimize nanomaterial surface area for catalytic applications?
Another method would be thinking of the chemistry of the reaction, and how reactants are reacting with the catalytic components at low concentration if the materials are precious. Borrowing insights from biology, it is possible to enhance avidity with polymeric materials to help transport and funnel reactants towards catalytic regions. This will aid to drive materials out of solution and back into the bulk environment after catalysis. Careful design of polymeric properties and screening of materials will allow for the materials to be developed. First begin with a control reaction in idealized conditions, then slowly make the environment or conditions more strict as optimization of the material improves.
Activity
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A big reason I just joined the board of Sphere Fluidics Limited is the huge demand I believe we'll see emerging for single cell platforms from the…
A big reason I just joined the board of Sphere Fluidics Limited is the huge demand I believe we'll see emerging for single cell platforms from the…
Liked by Devon Cayer
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Shared an inside look of our recent investments with investor connections this week (if you didn't get it and want it, lmk). One of my favorite stats…
Shared an inside look of our recent investments with investor connections this week (if you didn't get it and want it, lmk). One of my favorite stats…
Liked by Devon Cayer
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It's a real pleasure for me to announce that LCC has promoted Caroline Couturier to become LCC [Liverpool ChiroChem]'s Chief Financial Officer…
It's a real pleasure for me to announce that LCC has promoted Caroline Couturier to become LCC [Liverpool ChiroChem]'s Chief Financial Officer…
Liked by Devon Cayer
Experience
Education
Publications
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An enzyme-free, kinetically controlled, isothermal method for the “digital” detection of single nucleotide mismatches
Bioorganic & Medicinal Chemistry Letters
We describe an isothermal, enzyme-free method to detect single nucleotide differences between oligonucleotides of close homology. The approach exploits kinetic differences in toe-hold-mediated, nucleic acid strand-displacement reactions to detect single nucleotide polymorphisms (SNPs) with essentially “digital” precision. The theoretical underpinning, experimental analyses, predictability, and accuracy of this new method are reported. We demonstrate detection of biologically relevant SNPs and…
We describe an isothermal, enzyme-free method to detect single nucleotide differences between oligonucleotides of close homology. The approach exploits kinetic differences in toe-hold-mediated, nucleic acid strand-displacement reactions to detect single nucleotide polymorphisms (SNPs) with essentially “digital” precision. The theoretical underpinning, experimental analyses, predictability, and accuracy of this new method are reported. We demonstrate detection of biologically relevant SNPs and single nucleotide differences in the let-7 family of microRNAs. The method is adaptable to microarray formats, as demonstrated with on-chip detection of SNP variants involved in susceptibility to the therapeutic agents abacavir, Herceptin, and simvastatin.
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Mission critical: the need for proteomics in the era of next-generation sequencing and precision medicine
Human Molecular Genetics
Review covering the current state of multiplex proteomics.
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A modular and general Inhibitor-DNA-Enzyme (IDE) architecture for the isothermal, sequence-specific detection of oligonucleotides
UMI
Thesis Work: "Programmable biomolecules and their applications in diagnostics and therapeutics"
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Prediction of microRNA targets by evoking the endogenous microRNA target-site protection paradigm
UMI
Thesis Work: "Programmable biomolecules and their applications in diagnostics and therapeutics"
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Small molecule-DNA and antibody-DNA directed recruitment of an oligonucleotide regulated enzyme for selective cytotoxicity against tumor cell lines
UMI
Thesis Work: "Programmable biomolecules and their applications in diagnostics and therapeutics"
Patents
Honors & Awards
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Indiebio Accelerator Batch 2
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One of 14 biotech start-up companies selected to build a company in San Francisco for 4 months. Company, MYi Diagnostics and Discovery, received a 250K award for the program.
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Illumina Sequencing Grant
Illumina Accelerator
Upon being a finalist in the Illumina Accelerator Spring 2015 competition, was awarded an Illumina Sequencing Grant to aid in the development of MYi technology.
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Accepted in Y-Combinator S19 Batch
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Did not accept offer due to in-progress fundraise
Languages
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French
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Spanish
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Recommendations received
2 people have recommended Devon
Join now to viewMore activity by Devon
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Public feedback is the best feedback. It’s like defending a dissertation. Thanks Valentin Romanov for giving 🥔 a thorough shake!
Public feedback is the best feedback. It’s like defending a dissertation. Thanks Valentin Romanov for giving 🥔 a thorough shake!
Liked by Devon Cayer
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Antler US's latest batch is looking🔥 8,000 founder applications became 300 founders on-site across our offices in NYC, Boulder, and Austin -…
Antler US's latest batch is looking🔥 8,000 founder applications became 300 founders on-site across our offices in NYC, Boulder, and Austin -…
Liked by Devon Cayer
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Antler is releasing our spring additions to the portfolio! ✨ 8,000 founder applications, 8 weeks of building in our community, 32 investments A…
Antler is releasing our spring additions to the portfolio! ✨ 8,000 founder applications, 8 weeks of building in our community, 32 investments A…
Liked by Devon Cayer
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