Genetic Research in Human Reproduction
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: 15 November 2024 | Viewed by 159
Special Issue Editors
Interests: human molecular biology; reproductive medicine; human reproduction; embryology; andrology
Special Issues, Collections and Topics in MDPI journals
Interests: biochemistry; human molecular biology; reproductive medicine; human reproduction; embryology; andrology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Welcome to this Special Issue of our journal, dedicated to genetic research in human reproduction. Approximately one in six people of childbearing age worldwide faces infertility. Overall, fertility rates have been falling steadily for decades globally and in almost all countries and regions, and they are likely to continue falling in the future. Factors such as ovulation failure, spermatogenesis failure, parental age, obesity, infection, and genetic variation contribute to this complex problem. Studies on genes associated with infertility in rodent models have expanded the scope of translational genetics, but the molecular basis of human infertility remains to be fully elucidated. Despite extensive research, no genes have been identified for genetic testing for infertility, so new diagnostic techniques need to be developed. Genetic association studies have been performed to identify the genes causing infertility, and increasing the sample size is critical in identifying strong associations. Although the interpretation of high-throughput sequencing data poses challenges, whole-exome and whole-genome sequencing offer potential solutions.
The purpose of this Special Issue is to provide a comprehensive overview of the recent genetic research in the field of human reproduction, highlighting the complexities and possible solutions in this rapidly evolving field.
Dr. Houda Amor
Dr. Mohamed Hammadeh
Guest Editors
Manuscript Submission Information
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Keywords
- genetic research
- human reproduction
- male fertility
- female fertility
- translational genetics
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