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Making Medicine

Making Medicine is a story of big questions, breakthrough science, and a relentless desire to help people struggling with the world's most formidable diseases…
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20 Pins
 10y
Collection by
Genentech
a woman sitting at a table talking to someone
Making Medicine
People Struggle
Clinical Trials
It Takes
Helping People
Disease
Medicine
How To Become
Take That
How Clinical Trials Happen: Clinical Operations
http://gene.com/making - The clinical trial is central to understanding whether or not a molecule can ever become a medicine. It takes a tremendous amount of collaboration and dedication to make sure our medicines meet safety and efficacy standards.
a man standing in a factory looking up at something
Technology Transfer
Science Technology
The Science
Make Sure
We Need
To Work
Scaling the Science: Technology Transfer
http://gene.com/making - To manufacture enough medicines for all our potential patients, we need to work globally. We also make sure that the quality is consistently the same no matter where a medicine is manufactured.
a person is writing on a notebook with a pen in their hand while sitting at a desk
Use Data
Help People
Where Patients and Data Meet: Clinical Development
http://gene.com/making - We use data to understand how well the medicine works, for whom it's working and how it might further help people.
a person is drawing on a large screen
Lab
Science
Building
Building a Body of Evidence: Translational Medicine
http://gene.com/making - Sometimes the science in the laboratory doesn't exactly play out as we predicted in clinical trials. So we spend time refining our approach in the lab and in the clinic.
a woman sitting in front of a computer with a piece of paper on her lap
To Create
Cards Against Humanity
Targets, Mechanism, and Disease: Biomarker Development
http://gene.com/making - Biomarkers are measurable biological characteristics. We use them to deepen our understanding of disease and to create targeted medicines. Effectively using biomarkers is a collaborative effort that goes from early research to well after a medicine is approved.
two men in white lab coats are looking at a computer screen and pointing to it
Composition
More And More
The Body
Stuff To Do
Understanding Assays: Bioanalytical Science
http://gene.com/making - As our medicines get more and more complex so do the methods we use to understand how they work. In particular, we study how the chemical composition of the medicine interacts with the body.
two men sitting at a desk in front of computer monitors
Pharmacology
School Stuff
Bringing Medicines to the Body: PK/PD & Clinical Pharmacology
http://gene.com/making - Before a potential medicine ever enters a human body, we develop simulations to test how it might behave. We need to understand where it goes, how long it will persist, and if it will reach its intended target.
a person in purple gloves is checking the temperature on an electronic device with a digital clock
Stables
Canning
Keeping the Molecule Stable: Product Formulation and Delivery
http://gene.com/making - Medicines won't work unless they are stable and can be properly administered. We need to be clever to keep our biologics stable and intact after they leave Genentech.
an older man sitting in front of a group of people with glasses on his head
Assessment
Health Care
Novo Nordisk
Research Scientist
Managing Risk: Safety Assessment
http://gene.com/making - All medicines come with risk. It's important that we understand those risks sooner rather than later. We start with clinical development and continue to evaluate even after a medicine is approved.