D-mine Care

𝗗𝗶𝗱 𝘆𝗼𝘂 𝗸𝗻𝗼𝘄 𝘁𝗵𝗮𝘁 𝗮𝗻𝘁𝗶𝗼𝘅𝗶𝗱𝗮𝗻𝘁𝘀 𝗰𝗮𝗻 𝗽𝗿𝗲𝘃𝗲𝗻𝘁 𝗣𝗮𝗿𝗸𝗶𝗻𝘀𝗼𝗻'𝘀 𝗱𝗶𝘀𝗲𝗮𝘀𝗲? #Parkinson’s disease is driven by the loss of neurons responsible for producing dopamine, a key neurotransmitter involved in motor control and cognitive functions. Protecting dopaminergic neurons from damage caused by reactive oxygen species (ROS) is crucial, as current treatments only address symptoms rather than offering a cure or prevention. A recent study offers promising #insights, showing that antioxidants might reduce neuronal damage by activating AMPK (adenosine monophosphate-activated protein kinase) and inhibiting ROS production. In a mice model, Ecklonia cava polyphenols, a type of #seaweed #antioxidant, demonstrated potential in protecting neurons. By stimulating AMPK and preventing ROS generation, these antioxidants could play a significant role in preventing Parkinson’s disease. 📄 Reference: Yasuda, Y., et al. (2024) Ecklonia cava Polyphenols Have a Preventive Effect on Parkinson’s Disease through the Activation of the Nrf2-ARE Pathway. Nutrients.  🔗 Link to paper: https://lnkd.in/d-GfBUXi #dminecare #movementdisorder #scientific #disease #prevention

𝗢𝗿𝗶𝗴𝗶𝗻 𝗼𝗳 𝗵𝗮𝗹𝗹𝘂𝗰𝗶𝗻𝗮𝘁𝗶𝗼𝗻𝘀 𝗶𝗻 𝗣𝗮𝗿𝗸𝗶𝗻𝘀𝗼𝗻'𝘀 𝗱𝗶𝘀𝗲𝗮𝘀𝗲 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗰𝗵𝗼𝗹𝗶𝗻𝗲𝗿𝗴𝗶𝗰 𝗱𝗲𝗻𝗲𝗿𝘃𝗮𝘁𝗶𝗼𝗻 𝗿𝗮𝘁𝗵𝗲𝗿 𝘁𝗵𝗮𝗻 𝗱𝗼𝗽𝗮𝗺𝗶𝗻𝗲𝗿𝗴𝗶𝗰 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁. A recent #study published in the journal BRAIN reveals that visual hallucinations in Parkinson's disease (PD) are linked to reduced cholinergic activity in specific brain regions. 📄 https://lnkd.in/dqkD9BWW While traditionally attributed to dopaminergic treatments, these #hallucinations - affecting about 25% of late-stage PD patients - are now understood to stem from cholinergic denervation, particularly in the occipital, temporal, and frontal lobes. Using PET scans with so called [18F]FEOBV tracers on 38 PD Patients and 10 healthy controls, researchers observed significant cholinergic deficits in areas like the left precuneus and lingual gyrus among hallucinating patients. These findings emphasize the Perception and Attention Deficit (PAD) model, highlighting poor visual perception and impaired object attention as key factors for visual hallucinations in PD, which are worse with cholinergic hypoactivity. Lead researcher Emile d'Angremont advocates for larger, diverse studies and individualized treatments using cholinesterase inhibitors to address these deficits. 👉 Link to article: https://lnkd.in/dbh3jpR5 #dminecare #scientific #parkinsons #movementdisorder

👉 𝘋𝘦𝘶𝘵𝘴𝘤𝘩𝘴𝘱𝘳𝘢𝘤𝘩𝘪𝘨𝘦 𝘍𝘰𝘭𝘭𝘰𝘸𝘦𝘳 𝘢𝘶𝘧𝘨𝘦𝘱𝘢𝘴𝘴𝘵! Für alle Betroffenen von #Parkinson, Betreuer, medizinische Fachkräfte oder Interessierte: Am 📅 25.07.2024 von 🕓16:00-17:00 findet das kostenlose Webinar "Ernährung bei Parkinson" statt. Julia König, Ernährungsberaterin und Therapiespezialistin für Parkinson bei #EVERPharma und Co-Autorin des Buches "Gut Essen - Parkinson", teilt wertvolle Einblicke, wie Ernährung die Medikation und den Verlauf der Erkrankung beeinflussen kann. #dminecare #ernährungparkinson #diätologie

𝗪𝗵𝗮𝘁 𝗱𝗼𝗲𝘀 𝗮 𝗰𝗵𝗮𝗻𝗴𝗲 𝗶𝗻 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁 𝗺𝗲𝗮𝗻 𝗳𝗼𝗿 𝗿𝗲𝗹𝗮𝘁𝗶𝘃𝗲𝘀 𝗼𝗳 𝗣𝗮𝗿𝗸𝗶𝗻𝘀𝗼𝗻'𝘀 𝗽𝗮𝘁𝗶𝗲𝗻𝘁𝘀? As #Parkinson's disease progresses, many patients find that oral medications no longer control symptoms adequately. Oral medications have a therapeutic window where they work effectively without causing disruptive side effects. As Parkinson's progresses, this window narrows, making it harder to manage symptoms with oral #therapy alone. Continuous pump therapy offers a solution by providing a consistent delivery of medication, minimizing the fluctuations that can occur with oral medications (Schapira et al., 2009). However, a #treatment change can be daunting for #patients and their families. Patients and their families often have many questions and concerns about switching to pump therapy, such as: "𝘈𝘮 𝘐 𝘢𝘭𝘳𝘦𝘢𝘥𝘺 𝘢𝘵 𝘵𝘩𝘪𝘴 𝘱𝘰𝘪𝘯𝘵?" Here, understanding the progression of the disease and the limitations of the current therapy is a main subject. 🔗https://lnkd.in/g_5DtBrE "𝘞𝘩𝘢𝘵 𝘸𝘪𝘭𝘭 𝘵𝘩𝘪𝘴 𝘥𝘰?" Learning about how pump therapy works, and its potential benefits is important. 🔗https://lnkd.in/gt579dJu "𝘊𝘢𝘯 𝘸𝘦 𝘤𝘰𝘱𝘦 𝘸𝘪𝘵𝘩 𝘵𝘩𝘪𝘴?" Assessing the practicalities and logistics of managing pump therapy in daily life. 🔗https://lnkd.in/geJrtfT4 "𝘏𝘰𝘸 𝘸𝘪𝘭𝘭 𝘦𝘷𝘦𝘳𝘺𝘥𝘢𝘺 𝘭𝘪𝘧𝘦 𝘤𝘩𝘢𝘯𝘨𝘦?" Considering the impact on daily routines and family dynamics is necessary. 🔗https://lnkd.in/gyde6pa3 Family members often play a critical role in supporting the patient, already during the decision-making phase but also in the day-to-day management of the therapy. If you are interested in this topic, read more about it on our D-mine Care Blog: https://lnkd.in/dCt__dyx #dminecare #blog

𝗔 𝗰𝘂𝗿𝗿𝗲𝗻𝘁 𝘁𝗼𝗽𝗶𝗰 𝗮𝘁 𝗜𝗔𝗣𝗥𝗗 𝟮𝟬𝟮𝟰: 𝗧𝗵𝗲 𝗲𝗳𝗳𝗲𝗰𝘁 𝗼𝗳 𝗹𝗼𝗻𝗴-𝘁𝗲𝗿𝗺 𝗧𝗮𝗶 𝗖𝗵𝗶 𝘁𝗿𝗮𝗶𝗻𝗶𝗻𝗴 𝗼𝗻 𝗣𝗮𝗿𝗸𝗶𝗻𝘀𝗼𝗻'𝘀 𝗱𝗶𝘀𝗲𝗮𝘀𝗲 A study was conducted to examine the long-term effects of #TaiChi training on patients with #Parkinson's disease (PD). Two cohorts were followed from January 2016: one with Tai Chi training (143 patients) and a control group without #exercise (187 patients). Assessments were made at baseline and at three subsequent intervals. The study found that long-term Tai Chi #training slowed the progression of motor and non-motor symptoms and delayed the need for increased antiparkinsonian medications. 💡 Overall, Tai Chi provided long-term benefits for PD #patients by improving symptoms and reducing complications. 📄 Li G, Huang P, Cui S, et alEffect of long-term Tai Chi training on Parkinson’s disease: a 3.5-year follow-up cohort studyJournal of Neurology, Neurosurgery & Psychiatry 2024;95:222-228. 👉 Link to full paper: https://lnkd.in/d5DDstSg In line with this goes our #blog post that emphasises further positive effects of Tai Chi: 👉 Link to D-mine® Care Blog Post: https://lnkd.in/ddb-PcY6 #dminecare

The German Parkinson's Congress starts tomorrow and will last until Saturday! I'm looking forward to news about old and new treatment options. Will you be there too? I'll be holding an expert session on the #DatamineREPORT of the #DminePump at the #EVERPharma stand. Looking forward to seeing you there!

𝗧𝗼𝗱𝗮𝘆 𝗺𝗮𝗿𝗸𝘀 𝗪𝗼𝗿𝗹𝗱 𝗣𝗮𝗿𝗸𝗶𝗻𝘀𝗼𝗻'𝘀 𝗗𝗮𝘆 and we're proud to announce the launch of our revamped support for the Parkinson's community! Check out the newly redesigned D-mine® Care Blog, dedicated to providing valuable insights and resources for professionals dealing with #Parkinson's disease. We have focused on hands-on topics, navigating daily life with Parkinson's disease. We've organized our #blog posts into six easily accessible categories, making it simple to find the information you need. Whether you're seeking tips on practical items or exploring nutritional content, our blog has you covered. Curious to learn more? Follow the link to dive into the D-mine® Care Blog and empower yourself with the latest insights and subscribe to get informed about newly published posts. 👉 https://lnkd.in/gzaVc4PD Together, let's continue to raise awareness and support for those living with Parkinson's. #worldparkinsonsday #communitysupport #dminecare #practical #tips

𝗜𝘁'𝘀 𝗕𝗿𝗮𝗶𝗻 𝗔𝘄𝗮𝗿𝗲𝗻𝗲𝘀𝘀 𝗪𝗲𝗲𝗸 In #Parkinson's disease the dopaminergic depletion in the basal ganglia leads to motor and non motor symptoms, but as well to cognitive impairment. Let's take the opportunity to increase public awareness of the progress and benefits of brain research in Parkinson's disease, triggered by the global campaign from #FENS and Dana Foundation. In Parkinson's, the treatment options of cognitive and neuropsychiatric non-motor-symptoms are still poorly explored (Mantovani, 2023). Share with us your latest insights in the comments & take the challenge below! 💬 👉 Link to FENS: https://lnkd.in/e94tRb5x #baw #brain #movementdisorder #dminecare #challenge

𝗦𝘁𝗮𝗿𝘁𝗶𝗻𝗴 𝘁𝗼𝗺𝗼𝗿𝗿𝗼𝘄 – 💻 Virtual international conference "Movement Disorders Today", 15.-16.02.2024   The standard registration to this #virtual #conference is free, with the possibility to ask questions via chat. Besides all other interested professionals in the healthcare sector, the target groups of the event are #neurologists, #generalpracticioners, #psychiatrists and #physicaltherapists. Listen to top KOL’s such as K Ray Chaudhuri on 15th of February about "#Pain in Parkinson’s disease" at 18:10 CET.   👉Read more about the full scientific programme here : https://lnkd.in/du9Nkvvs 👉 Or get registered right away : https://pan.ac/mdt2024reg #education #dminecare #parkinson #movementdisorder #scientificupdate

𝗡𝗜𝗖𝗘 𝗥𝗲𝗰𝗼𝗺𝗺𝗲𝗻𝗱𝗮𝘁𝗶𝗼𝗻𝘀 𝗼𝗻 𝘁𝗿𝗲𝗮𝘁𝗶𝗻𝗴 𝗮𝗱𝘃𝗮𝗻𝗰𝗲𝗱 𝗣𝗮𝗿𝗸𝗶𝗻𝘀𝗼𝗻´𝘀 𝗱𝗶𝘀𝗲𝗮𝘀𝗲. Apomorphine well positioned by NICE guidance. 📄 Source: https://lnkd.in/dDdhBzyJ The recommendations in this guidance represent the view of #NICE, arrived at after careful consideration of the evidence available. Treatment for advanced levodopa-responsive Parkinson’s includes adding Apomorphine, deep brain stimulation or levodopa–carbidopa intestinal gel to standard care (such as oral levodopa–carbidopa). Foslevodopa–foscarbidopa is recommended as an option for treating advanced levodopa-responsive Parkinson’s in adults whose symptoms include severe motor fluctuations and hyperkinesia or dyskinesia, when available medicines are not working well enough, only if they cannot have Apomorphine or deep brain stimulation, or these treatments no longer control symptoms. #parkinson #guidance #dminecare