Gabriel Levin, PhD

Investigated the functional characterization of cellular, humoral and innate immune responses in patients with COVID-19.

Performed search and analysis of scientific/medical information, including the creation of bibliographic reference banks on specific topics, stakeholders mapping and issuing technical opinions so that companies could make better business decisions based on scientific knowledge; Participated in corporate meetings with technical and commercial teams to understand demands related to the pharmaceutical industry and agribusiness; Generated scientific dissemination content for different audiences;… Exibir mais

Performed search and analysis of scientific/medical information, including the creation of bibliographic reference banks on specific topics, stakeholders mapping and issuing technical opinions so that companies could make better business decisions based on scientific knowledge; Participated in corporate meetings with technical and commercial teams to understand demands related to the pharmaceutical industry and agribusiness; Generated scientific dissemination content for different audiences; Implemented management tools and action plan. Exibir menos

• Operated GMP facility, according to local regulations (Anvisa), for biopharmaceuticals production;
• Generated genetically modified human and murine cell lines, producing complex proteins with therapeutic effect (RSPO1, VEGF, Glycoproteins);
• Established new purification protocols for recombinant proteins;
• Evaluated the biological activity of therapeutic proteins in in vitro and in vivo assays;
• Established collaborations with other national and international research… Exibir mais

• Operated GMP facility, according to local regulations (Anvisa), for biopharmaceuticals production;
• Generated genetically modified human and murine cell lines, producing complex proteins with therapeutic effect (RSPO1, VEGF, Glycoproteins);
• Established new purification protocols for recombinant proteins;
• Evaluated the biological activity of therapeutic proteins in in vitro and in vivo assays;
• Established collaborations with other national and international research groups that resulted in the publication of scientific articles;
• Participated in the preparation of the group's biosafety manual and standard operating procedures (SOPs);
• Published several works in respected international scientific journals and in events;
• Managed research projects, including planning, execution, budget management, reporting and accountability; Exibir menos

Research Internship Abroad/RIA
• Optimized the Tissue Engineered Small Intestine formation process in the laboratory, aiming at clinical alternatives for autologous intestinal transplantation;
• Designed and implemented zebrafish preclinical study protocols for therapies based on biological drugs administration, specifically to establish alternative therapies for short bowel syndrome treatment;
• Interacted with doctors and key opinion leaders to find therapeutic alternatives for the… Exibir mais

Research Internship Abroad/RIA
• Optimized the Tissue Engineered Small Intestine formation process in the laboratory, aiming at clinical alternatives for autologous intestinal transplantation;
• Designed and implemented zebrafish preclinical study protocols for therapies based on biological drugs administration, specifically to establish alternative therapies for short bowel syndrome treatment;
• Interacted with doctors and key opinion leaders to find therapeutic alternatives for the treatment of pediatric patients in the future;
• Interacted with the Innovation Department to assess the possibility of new therapeutic technology patenting;
• Managed a research and budget project, communicating the obtained results in weekly group meetings, in an oral presentation to the department and in a final activity report submitted to the funding agency, also producing manuscripts for publication of articles in scientific journals;
• Collaborated with the execution of scientific research applied to tissue regeneration, processing rare samples from human patients (hirschsprung disease) and following pre-clinical protocols of tissue therapy in mini pigs;
Project: Analysis of the Therapeutic Potential of the Human Recombinant R-Spondin1 Protein in Regeneration of Small Intestine in an Animal Model Using Tissue Engineering Technologies.
Advisor: Dr. Tracy C. Grikscheit, MD
Financial support: Foundation for Research Support of the State of São Paulo (FAPESP) Exibir menos

• Managed the flow cytometry/FACS equipment operation services, providing technical and intellectual support to the group and third-party research, including staff training, operator team coordination, inventory and financial resources management;
• Operated the flow cytometry/FACS equipment in the most diverse experiments, with different types of sample and multiparametric tests.

• Characterized the expression profile of genes related to tissue remodeling during the reproductive cycle in mice.
Project: Evaluation of MMPs, TIMPs, RECK, SPARC and Bsg expression during rat ovarian dynamics.
Advisor: Prof. Dr. Mari Cleide Sogayar
Co-advisor: Dr. Ana Claudia Oliveira Carreira
Financial support: Foundation for Research Support of the State of São Paulo (FAPESP)