🚀 We're thrilled to be back at the EuroBioC conference this year! Beyond sponsoring the event, we’re also excited to present our latest work on the NPmatch algorithm—a nearest-pair matching solution designed to tackle the challenge of batch effects in omics studies. In a field where reproducibility and reliability are critical, NPmatch offers a promising and fast approach to correct technical or experimental biases and allows a more reliable comparison across samples, experiment batches or even datasets. Don’t miss the chance to dive deeper—meet our representative, Antonino Zito, at the conference! ✨ We can't wait to reconnect with the Bioconductor community. See you there! #EuroBioC2024 #bioconductor #bioinformatics
BigOmics Analytics
Biotechnologieforschung
Lugano, Ticino 4.694 Follower:innen
Democratizing omics data analytics.
Info
At BigOmics, we are committed to empowering researchers in omics data analysis. Our Omics Playground is an intelligent omics data analysis platform that empowers biologists to perform complex analysis and visualization themselves and helps bioinformaticians delegate routine analysis. Governed self-service bioinformatics provides you with a powerful solution to fast-track your bioinformatics needs.
- Website
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http://www.bigomics.ch
Externer Link zu BigOmics Analytics
- Branche
- Biotechnologieforschung
- Größe
- 11–50 Beschäftigte
- Hauptsitz
- Lugano, Ticino
- Art
- Privatunternehmen
- Gegründet
- 2018
- Spezialgebiete
- bioinformatics, transcriptomics, proteomics, omics data analysis und big omics data
Produkte
Omics Playground
Bioinformatik-Software
Omics Playground is an online self-service analytics platform that empowers life scientists to perform complex analysis and visualization by themselves, without the need to learn how to code. The platform focuses on the tertiary analysis (i.e. interpretation) of transcriptomics (e.g. micro-array, RNA-seq, scRNA-seq) and proteomics data, providing you with highly interactive visualization tools to understand your data. - More than 18 interactive modules - More than 100 HQ plots - Best-in-class algorithms - Cloud-based and open source. Try it now at: https://public.bigomics.ch/.
Orte
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Primär
Via Serafino Balestra 12
Lugano, Ticino 6900, CH
Beschäftigte von BigOmics Analytics
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Lorenzo Leoni
Scientific Serial Entrepreneur, Investor, Mentor, Life-enthusiast. Managing Partner at TiVentures and Creadd Ventures
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Dr. Jochen Mueller-Ibeler
Head of New Business Development - Eppendorf Innovation Company (EpIC) - Life Science Expert
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Markus Gröninger
CEO & Founder edux gmbh
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Axel Martinelli
Head of Biology at BigOmics Analytics
Updates
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BigOmics Analytics hat dies direkt geteilt
With the increasing amount of publicly available RNA sequencing data, scientists can now contextualize their results, create data-driven hypotheses, and uncover trends across different studies. Here are the top 5 public databases for RNA-seq data: ➡️ The Gene Expression Omnibus (GEO) hosted by The National Institutes of Health. ➡️ The Expression Atlas hosted by EMBL. ➡️ The Genotype-Tissue Expression (GTEx) hosted by the Broad Institute of MIT and Harvard. ➡️ The Cancer Genome Atlas (TCGA), maintained by the NIH. ➡️ Recount3 from the Langmead lab. Discover more about each repository and how to access them at 👉 https://lnkd.in/ewsR2Kgy -- Compare your data to 6000+ public datasets with Omics Playground! Learn more at https://lnkd.in/eUnFPwEt ✨ #bioinformatics #computationalbiology #rnaseq #publicdatabases #omicsdata #omicsdatabases
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Yesterday's seminar at EMBL's GeneCore Facility was a fantastic experience! We had the pleasure of discussing how to streamline collaboration by easily sharing omics data and insights using our Omics Playground platform 🤝🚀 We explored various applications using a glioblastoma dataset, including: 🔍 Basic analyses 📊 Comparing experiments 🔬 Biomarker discovery 💊 Drug connectivity Thank you to everyone who attended, and a big shoutout to EMBL for their incredible hospitality. Special thanks to Jonathan Landry, Vladimir Benes, and Jan Provaznik—it was wonderful meeting you all in person. Looking forward to further collaborations ahead! #rnaseq #proteomics #omicsdata #bioinformatics #computationalbiology #biomarkerdiscovery #drugconnectivity #omicsplayground
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How does WGCNA work, what can you expect from the approach in your next RNA-seq study, and what are its limitations? Weighted gene co-expression network analysis (WGCNA) is a powerful all-in-one analysis method that allows biologists to understand the transcriptome-wide relationships of all genes in a system rather than each gene in isolation. Discover the four steps of WGCNA and learn to perform it interactively with Omics Playground! Read the full blog post at ➡️ https://lnkd.in/egBk6NgM #WGCNA #omicsdata #rnaseq #transcriptomics #bioinformatics #computationalbiology #omicsplayground
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Great example of how you can now use our Omics Playground platform to analyze plant datasets 🔍 Try it now at https://lnkd.in/eUnFPwEt ✨ #plantbiology #plantscience #transcriptomics
For this post, I decided to explore our expanded species feature that now allows Omics Playground (OP) to support more than 1000 species, including most crops and fruit trees. I thus found a recently published dataset (https://lnkd.in/eyTn_VCg) by Torsten Möhlmann and colleagues of the University of Kaiserslautern (TU-KL) on the role of uracil phosphoribosyltransferase (UPP) in chloroplast function in the model plant Arabidopsis thaliana. In this study, the authors exposed both Wild Type (WT) and UPP knock-down (KD) plants to high light or medium light (control) for three hours and then sequenced their transcriptomes. Through OP I first of all identified the typical signatures of high light stress induced in both WT and KD plants, with the latter exhibiting a more marked upregulation of genes associated with stress, such as responses to UV light, as well as the upregulation of Flavonoid and vitamin B6 biosynthesis (Fig. 1A). This was further supported by using the Biomarker discovery module, which identified a significant upregulation of both ELIP1 and ELIP2 genes under high light conditions and an even more marked increase in KD plants (Fig. 1B). Both genes are typically upregulated during exposure to high light stress conditions. Additionally, the gene RPP2D (a cytosolic ribosomal protein located in the chloroplast) is downregulated in KD plants (data not shown), which could indicate its involvement in the chloroplast proteostatic function of UPP, as suggested by the authors in their article. Finally, the platform also utilized the Drug Connectivity Map database to highlight the potential protective role of Histone Deacetylase (HDAC) inhibitors against high light exposure (Fig. 1C), aligning with their known roles as regulators of stress responses in plants and the antioxidant properties of some HDAC inhibitors. To conclude, the platform was able to capture the main aspects of high light stress in A. thaliana, underscores the more extreme upregulation of stress-induced genes in UPP KD plants and finally suggest HDAC inhibitors as a mode of action to protect plants from high light expose. #Plants #Athaliana #RNAseq #transcriptomics #OmicsPlayground #Photosynthesis
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BigOmics Analytics hat dies direkt geteilt
It is a great pleasure for us to present BigOmics Analytics at the Swiss Proteomics Annual Meeting organized by Life Sciences Switzerland (LS2). Together with my colleagues Axel Martinelli and Antonino Zito we are happy to discuss the analysis and discovery of proteomics data using Omics Playground. In particular, we have two oral presentations today where we discuss the analysis of Olink Proteomics datasets using the platform by Axel and detailed guidelines on normalization and imputation of missing values for Mass Spec datasets by Antonino. Looking forward to a fruitful discussion. #Proteomics #Omics #MassSpec #Olink #DataDiscovery #OmicsPlayground
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Struggling to handle proteomics data analysis quickly, manage its complexity, and foster collaboration with partners? It's no easy task. But with Omics Playground, you can achieve all that and more! When dealing with proteomics data, challenges like complex protein analysis of large datasets can arise. Partners in research collaborations often find dealing with such data complexity challenging, and the time required for analyses can be significant. Discover how Omics Playground has helped our clients at the Universität zu Lübeck overcome these hurdles and: ✔️ Achieved significant time savings in data analysis. ✔️ Reduced the complexity of their data. ✔️ Facilitated easier sharing of data sets among collaborators. “Omics Playground offers a really large number of analysis options – and new ones are added regularly. It's remarkable that everything works so well and integrates so well, with access to many databases and information sources. All this after only 20-30 minutes of computing time is pretty impressive.” says Prof. Timo Gemoll, Head of the Section for Translational Surgical Oncology and Biomaterial Banks at the University of Lübeck. Want to know more on how Omics Playground could transform your proteomics research? Read our case study below! 👇 https://lnkd.in/eN24Rgdq #proteomics #bioinformatics #computationalbiology
Fast and Flexible Omics Data Analysis for Proteomics Research in Oncology
http://bigomics.ch
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🎉 It's Day 1 of the Festival of Genomics & Biodata in Boston! Join us at Booth 76 to chat with our team about omics data analysis and explore the Omics Playground platform. Plus, don't miss out on our fantastic swag! See you there! 🌟 #FOGBoston Front Line Genomics #omics #bioinformatics #computationalbiology
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Last Friday, we had an Omics Playground training session with our amazing users at Plexium 🧬 During this session, we covered: ➡️ Insider tips and tricks for maximizing the benefits of Omics Playground. ➡️ The newest updates designed to enhance the data discovery experience. ➡️ Insights into Plexium's current projects and how they are leveraging Omics Playground to achieve their research goals. Thank you to everyone who participated ✨ Your feedback is crucial to our continuous improvement. We're thrilled to see the ways you’re using the platform! We look forward to continuing this journey together 🚀 #omicsplayground #clienttraining #bioinformatics #computationalbiology #biotech #rnaseq #proteomics #omics
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What an incredible experience at #ASMS2024! 🎉 A huge thank you to everyone who stopped by our booth, shared your research, and provided invaluable feedback. Your insights are what drives us to keep innovating and improving! It was great to connect with so many passionate researchers and professionals, and to meet some of our clients, Stephanie Byrum, PhD, and Craig Stumpf in person along the way! We’re excited about the future of proteomics and can’t wait to contribute to it with our interactive tools in Omics Playground, designed to accelerate data discovery and drive groundbreaking research. Thank you, American Society For Mass Spectrometry (ASMS), for hosting such a great event 🙌 #proteomics #massspec #bioinformatics #computationalbiology #biotech #pharma
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