Journal of Ageing and Longevity MDPI

☀ At the end of this work week, JAL is inviting you to read the Article "Skeletal Muscle Transcriptome Alterations Related to Declining #PhysicalFunction in Older Mice" by Ted G. Graber, Rosario Maroto, Jill K. Thompson, Steven G. Widen, Zhaohui Man, Megan L. Pajski and Blake B. Rasmussen. 💡 "We hypothesized that relationships exist between age-related differentially expressed genes (DEGs) in skeletal muscle and age-associated declines in physical function and exercise capacity. Previously, male C57BL/6mice (6m, months old, 24m, and 28m) were tested for physical function using a composite scoring system (comprehensive functional assessment battery, CFAB) comprised of five well-validated tests of physical function. In this study, total RNA was isolated from tibialis anterior samples (n = 8) randomly selected from each age group in the parent study. Using Next Generation Sequencing RNAseq to determine DEGs during aging (6m vs. 28m, and 6m vs. 24m), we found a greater than five-fold increase in DEGs in 28m compared to the 24m. Furthermore, regression of the normalized expression of each DEG with the CFAB score of the corresponding mouse revealed many more DEGs strongly associated (R ≥ |0.70|) with functional status in the older mice. Gene ontology results indicate highly enriched axon guidance and acetyl choline receptor gene sets, suggesting that denervation/reinnervation flux might potentially play a critical role in functional decline. We conclude that specific age-related DEG patterns are associated with declines in physical function, and the data suggest accelerated aging occurring between 24 and 28 months." 🔗 To access full manuscript, please visit: https://lnkd.in/d9M8Qk5F

☀ This Thursday we invite you to read the Article "Artful Ageing, Not Just Successful Ageing" by Tine Fristrup and Jon Dag Rasmussen. 💡 "The perspective unfolded throughout the article is a philosophical venture, or, rather, a preliminary work, developing the concept of artful ageing as a tool applicable in rethinking and broadening the range of activities occurring in institutional settings dedicated to older adults. Furthermore, the perspective also presents a critical stance towards normative footings and biopolitical agendas embedded in current regimes of active ageing. Artful ageing represents the ambition to enable and support artful lives, events, and activities among residents and participants in care homes and other contexts. " 🔎 To find out more, please visit: https://lnkd.in/dMn9VpXk

🔔 Special Issue "The Role of Hospitality in Ageing and Longevity: A New Frontier for Ageing in Place and Senior Living" 🎓 Guest Editor: Prof. Dr. Thorsten Merkle 📆 Deadline: 31 December 2024  🔗 More information: https://lnkd.in/dTyrKRMC

🎮 Today JAL invites you to read an interesting Protocol "Efficacy of the Use of Exergames in Promoting the Mental Health of the Elderly: Protocol of a Systematic Review" by Andreia Lima, Maria Teresa Moreira, Maria Salomé Ferreira, Vítor Parola, Francisco Sampaio, Maria do Perpétuo Nóbrega and Carla Fernandes. 💡 Scientific and technological advancements have significantly impacted our daily lives, and it is not easy to imagine living without their benefits. However, elderly individuals may experience limited access to these resources, impeding their autonomy. To address this, the use of exergames has been proposed to promote the mental health and socialization of older people. This study aims to systematically review the effectiveness of exergames in promoting older people’s mental health and socialization. 🔗 Access to the full Protocol: https://lnkd.in/dYXzUg_7

📢 We are proud to announce the 1st publication in the Special Issue Aging in Place: Supporting Older People's Well-Being and Independence: https://lnkd.in/d7SFRqc8 📜 Article "Feasibility and Usability of an Occupation-Based Immersive Virtual Reality Protocol for Older Adults" by Sara Benham, Alexis Cruz, Ashley Oliva, Franz Osol, Elizabeth Strona, Stephanie Kolakowsky-Hayner and Ann Marie Potter. 💡 This study aimed to explore the experiences and perceptions of older adults engaging with a client-centered immersive virtual reality (IVR) protocol tailored to their specific occupational interests. Employing a mixed methods approach, the research combined the quantitative System Usability Scale (SUS) assessment with qualitative interviews to examine the feasibility, usability, and learning experiences of community-dwelling older adults. 🔗To access full manuscript, please visit: https://lnkd.in/djaqnumC

🔔 Special Issue: Medication Management and Medication Safety in Older Adults 🎓 Guest Editor: Dr. Carol Fox 📅 Deadline: 30 November 2024 🔗 More information: https://lnkd.in/dM2cBneE

⭐ This Friday, we invite you to read the Article "The Relationship between Mental Health and Loneliness in the Elderly during the COVID-19 Pandemic" by Mahsa Sadatnia, Amir Jalali, Laili Tapak and Farshid Shamsaei. 💡 In this cross-sectional study, 211 retirees of Kermanshah University of Medical Sciences were selected by available sampling method in 2021. The study aimed to investigate the relationship between mental health and loneliness among seniors during the COVID-19 pandemic. 🔎 To discover more about this topic, please visit: https://lnkd.in/dYj8Z_6N

🌏 This Wednesday, JAL invites you to read a Brief Report "Trends in #Octogenarian #Pathology" by Tal Keidar Haran, Arnon Haran and Nir Pillar. 💡 Authors investigated the trends in pathological specimen submissions from patients aged 85 or older over ten years at a single center. They observed a nearly two-fold increase in submissions during 2015–2019 compared to 2010–2014, out of proportion to the change in the fraction of older adults in the population, suggesting a changing attitude towards medical care in these older patients. Dermatologic samples were the main driver of growth, followed by gastrointestinal and urinary tract samples. However, other samples, like breast and lung, did not significantly increase. Although further research is needed to understand the implications of increasing invasive procedures in the oldest old, a noteworthy trend has emerged towards increased and more active healthcare for this population. Healthcare providers and administrators should be prepared for a continued rise in invasive interventions in this age group. To find out more, please visit: https://lnkd.in/dehdMZcz

👉 We welcome you to read the Article "Empowering Older Adults in Underserved Communities—An Innovative Approach to Increase Public Health Capacity for Fall Prevention" by Subi Gandhi, Laurie Long, Viraj Gandhi and Muna Bashir. 💡 "In this cross-sectional study, a multi-agency approach was adopted for integrating an evidence-based program, A Matter of Balance (AMOB), into the public health curriculum at a rurally placed university. We assessed student learning as well as the community benefits of fall prevention among those who participated in the AMOB program. Eighty-four percent of the students reported intentions of using AMOB training in their future careers. " 🔎 To find out more, please visit: https://lnkd.in/dKgjiXE5

👪 We are inviting you to read the Article "Social Connectedness in a Locked-Down World: A Phenomenological Study of OlderAdults during the COVID-19 Pandemic" by Amy Beardmore, Penny Beynon, Christine Crabbe, Jan Fullforth, Jeremy Groome and Matthew Jones from the  University of the West of England, UK. 💡 In-depth interviews with 13 older people were conducted between March and May 2021. These interviews explored the participant’s lived experiences of staying socially connected to others during the enforced lockdowns and various restrictions. Results reveal strong themes of personal resilience, sense of coherence and other protective factors, but also highlight the benefits of establishing connections to friends, family, organised groups and community prior to the pandemic. 🔎  To find out more about this article visit: https://lnkd.in/dcgGpr8U