Bactolife

Everything we do is grounded in science, which is why we are thrilled to share our latest scientific publication published today in Wiley Protein Science entitled “Fit-for-purpose heterodivalent single-domain antibody for gastrointestinal targeting of toxin B from Clostridium difficile”. Read the full story here: https://lnkd.in/d7M8zz9m In the paper we provide insights into how we have developed a thorough, systematic, and efficient in vitro screening methodology for qualification of each of our Binding Proteins. This is how we can guarantee that we deliver impactful and versatile ingredients for a variety of food applications. This publication would not have been possible without our incredible research team, especially Everardo Remi Rodriguez Rodriguez, Rune Nordvang, Marcus Petersson, Jakob Kræmmer Haar Rendsvig, Emma Wenzel Arendrup, Andreas Laustsen-Kiel, and Sandra Wingaard Thrane. A special thanks goes to our collaborators from DTU - Technical University of Denmark and Scripps Research Monica Fernández-Quintero and Timothy Jenkins.

Andreas Laustsen-Kiel, our co-founder, scientific advisor, and board observer, is a remarkable leader. Beyond co-founding Bactolife, he has played a key role in the founding of seven other companies. He also directs the Center for Antibody Technologies at DTU - Technical University of Denmark. To say we are proud and fortunate to have Andreas on our team is an understatement. A recent article in Nature highlights some of the impactful work he has done for the scientific community and his mission to improve lives around the world.

New research suggests the primary cause of C. difficile infection is not person-to-person transmission but comes from within people themselves. Hospitals are known hotspots for Clostridiodes difficile infections, particularly among patients with weakened immune systems or recent antibiotic use. It was previously believed that person to person was the main cause of spread. But a study at Rush University Medical Center found that 60% of ICU patients who developed C. difficile infections already carried the bacteria when they arrived to the hospital. And only 6 out of 32 patiens were infected from patient to patient. Silent carriers of C. difficile may play a larger role in hospital infections than previously thought, creating a need for more effective screening upon admission and refined infection control strategies to better protect vulnerable patients. Read the full article here: https://lnkd.in/eR6WGC5r #GutHealth #GutMicrobiome #ClostridioidesDifficile

"Suddenly we understand that we are not just our own cells, we are the combination of everything that is in us, and we need to take that into account in how we act, develop products, and live our life." This powerful insight from Sandra Wingaard Thrane during the Food Tech Congress reminds us that our health is a collaboration between our cells and the community of microorganisms that live with us. 🌱 At Bactolife, this is core to our belief—developing ingredients that respect and nurture this delicate balance.

ZOE's Team PROSPECT has been awarded a £20 million grant from Cancer Grand Challenges, supported by the Bowelbabe Fund, to investigate the increasing rates of early-onset cancers in adults and develop new methods to assess risk and prevent colorectal cancer. This research is not just about studying cancer, but about understanding how nutrition and gut health can help turn the tide on early-onset cancers, particularly colorectal cancer. We are hopeful that research like this can create a future where fewer lives are touched by cancer. Congratulations Zoe!

Is this all you gut? We gave it our all at the DHL Relay Run this Monday with several running and walking teams! Thank you to everyone who participated! The DHL Relay in Copenhagen has become a Bactolife tradition, and with the Olympics just behind us, it feels like perfect timing. Especially with our project director Rune Nordvang running 3 laps on his own, 15 kilometers in total! What do you think of our new athletic shirts? We may not have won the race, but we definitely took home the best-dressed award! 😎 We had a great time and already look forward to next year's DHL run. #Bactolife #BindingProteins #Running #Health

Why is it that for every bacteria officially diagnosed as causing gut issues, 127 go undiagnosed? Underdiagnosis and underreporting are creating a significant gap in our understanding, especially in developing countries where the challenge is even greater. The main issue is the lack of a quick and affordable diagnostic method. The process is complicated, involving several steps: taking a sample, sending it to a lab, and waiting for results. To detect all pathogens, not just the common ones, specialized equipment is often needed, which further increases the cost and complexity. Poor gut health remain a major global issue in need of innovative solutions. #GutHealth #HealthInnovation #GlobalHealth

Bactolife recently turned 7! From a few offices at DTU to our own offices with now more than 40 people from 14 different countries, and 5 published papers (with more coming). Seven years ago, we set out to empower worldwide health through a fortified gut microbiome, by making Binding Proteins accessible to all - Today, due to our amazing team and the support of our incredible partners and investors, we are closer to that dream than ever. If you're curious to learn more about how Bactolife got started, we have a podcast epsiode that Sandra Wingaard Thrane and Sebastian Søderberg did with Søren Spanner Bach Bach earlier this year. Listen to the episode on Spotify: https://lnkd.in/gXg3sgQP Thank you to everyone who has been part of this journey with us. We could not have come this far without your support, and we look forward to what we will achieve together in the years to come. #GlobalHealth #MicrobiomeInnovation #BindingProteins

Foodborne illnesses are more common than many realize. Just recently, the FDA issued a warning to stop an outbreak of Campylobacter linked to Maine oysters harvested between June 19th and July 16th. These oysters were distributed to restaurants and food retailers across U.S. states and Ontario, Canada. Why does this matter? Campylobacter is a harmful bacterium that can cause severe foodborne illnesses. Symptoms like diarrhea, abdominal pain, fever, and nausea can appear within two to five days of exposure. In severe cases, the infection can lead to life-threatening complications. Such infections result from consuming contaminated food or beverages, and can quickly disrupt the gut health of thousands. While food safety practices are important in minimizing these risks, no system is perfect. The FDA's quick response to this situation was an important and good step in preventing a larger public health issue. Source: https://lnkd.in/em8cj3ie #FoodSafety #PublicHealth #Campylobacter