Analysis of animal-to-human translation shows that only 5% of animal-tested therapeutic interventions obtain regulatory approval for human applications
Fig 6
Meta-analysis on concordance rate between animal and human studies (relative risk).
Forest plot of concordance rates (relative risks) between animal and human studies. A random-effects model was fitted to the data. The data underlying this figure can be found on https://osf.io/frjm4 (Sheet: Mastersheet_including_RoB). The code underlying this figure can be found S1 Code (https://osf.io/9fgru). CI, confidence interval; RR, relative risk.
doi: https://doi.org/10.1371/journal.pbio.3002667.g006