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OpenAI announced that chief technology officer Mira Murati will step in as interim CEO.
After Altman's ouster, president Greg Brockman also left the company.
Also read | Meet Mira Murati, the engineer leading OpenAI after Sam Altman's ouster
OpenAI’s board of directors include chief scientist Ilya Sutskever, Quora chief executive Adam D’Angelo, tech entrepreneur Tasha McCauley, and Helen Toner, director of strategy and foundational research grants at Georgetown University's Center for Security and Emerging Technology.
"Altman's departure follows a thorough review process by the board, concluding that he was not consistently transparent in his communications, hindering the board's ability to fulfill its responsibilities. The board no longer has confidence in his ability to continue leading OpenAI," the company said in its blog.
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Altman’s ouster followed wide-ranging disagreements between the CEO and his board — in particular Sutskever, according to Bloomberg.
Also read | Sam Altman and I are shocked, saddened by what OpenAI board did today: Greg Brockman
The debates included differences of opinion on AI safety, the speed of development of the technology and the commercialization of the company.
A month ago, Sutskever’s responsibilities at the company were reduced, reflecting friction with Altman and Brockman.
Altman took to X (formerly Twitter) to announce his departure. "I loved my time at openai. it was transformative for me personally, and hopefully the world a little bit. Most of all I loved working with such talented people. Will have more to say about what’s next later," he posted on the platform.
Also read | 'Saddened by what’s transpired': Business leaders react to OpenAI CEO Sam Altman's ouster
"Today was a weird experience in many ways. but one unexpected one is that it has been sorta like reading your own eulogy while you’re still alive. the outpouring of love is awesome," he said in a separate post on the microblogging platform.
Later on Friday, cofounder Greg Brockman said he would resign from the company.
This came a few hours after OpenAI’s board said Brockman would step down as chairman of the board but continue as the president of the company, reporting to the CEO.