🎉 Exciting News for Our Consortium! 🎉 We are thrilled to share that a new article has just been published in Protein Science by Dr Efstratios Stratikos' lab, featuring contributions of members of our consortium: ESR3 Galateia Georgaki and a collaboration with Prof. Peter van Endert's lab. 🧬🔬 Α unique novel small molecule inhibitor of the Insulin Regulated Aminopeptidase (#IRAP) is described. This compound constitutes the first IRAP inhibitor targeting the active site that utilizes a conformation-specific mechanism of action, provides insight into the intricacies of the IRAP catalytic cycle, and highlights a novel approach to regulating IRAP activity by blocking its conformational rearrangements. Congratulations to all the co-authors for this work! 🌟 Dive into the research and discover more about it in the following link👇 https://lnkd.in/dPJhcy3N #research #msca #CAPSTONE_H2020 #collaboration #proteinscience
CAPSTONE_H2020
Recherche en biotechnologie
CAPSTONE is an EU-funded project under H2020 that brings together experts in research on ERAP aminopeptidases.
À propos
CAPSTONE (Controlling Antigen Processing in Autoimmune diseases and Cancer) PhD project is a multi-disciplinary platform of experts in structural biology, immunology, biochemistry, proteomics, and therapeutics that jointly aim to increase the impact of research into ERAP aminopeptidases in various aspects of human and animal disease. The main goal of the CAPSTONE project is to train the next generation of researchers for interdisciplinary and intersectorial careers in basic and applied medicinal chemistry, immunomodulation and pharmacology research with full understanding of the requirements of academia, pharmaceutical companies and societal challenges.
- Site web
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http://www.capstone-etn.eu/
Lien externe pour CAPSTONE_H2020
- Secteur
- Recherche en biotechnologie
- Taille de l’entreprise
- 11-50 employés
- Siège social
- Lille
- Type
- Établissement éducatif
- Fondée en
- 2021
Lieux
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Principal
3 rue du Professeur Laguesse
F-59006 Lille, FR
Employés chez CAPSTONE_H2020
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Filipa Vasconcelos
PhD Candidate - ESR14 CAPSTONE-ETN Marie Sklodowska-Curie grant
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Martha Nikopaschou
Early Stage Researcher at @CAPSTONE_H2020 | PhD Candidate at NCSR "DEMOKRITOS"
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Nikoletta Koutroumpa
PhD Candidate Researcher at NTUA - Early Stage Researcher at CAPSTONE_H2020 - Cheminformatician at NovaMechanics Ltd
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Paula Gragera Álvarez
PhD student | Marie Skłodowska Curie Actions H2020 Early Stage Researcher at CAPSTONE-ETN
Nouvelles
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🚀 Highlight 8: Galateia Georgaki (ESR3) from NCSR "DEMOKRITOS", in #Athens, presented her work at the 48th FEBS Congress in #Milan 🌟🔬
🌟 I'm pleased to share that I recently attended the 48th FEBS Congress in #Milan , focusing on biochemistry and molecular biology. 🌟 It was a great opportunity to learn from and connect with experts in the field. The entire experience, including the insightful sessions and networking with peers, was truly enriching. 🚀 💡 I was particularly honored to present my poster and share my research findings from the CAPSTONE_H2020 project, focusing on the mechanistic basis of the #autoimmunity-protective allotype 10 of ER aminopeptidase 1. 🔬 💡 📢 Thank you to everyone who made this event memorable. 🌞 #FEBS2024 #Milan #Biochemistry #MolecularBiology #enzymes #antigenpresentation #autoimmunity #research #PhD #CAPSTONE_H2020 #msca
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🚀 Highlight 7: Kamila Król (ESR10) from the Ospedale Pediatrico Bambino Gesù, in Rome, presented her research work at the 6th SIICA International Conference of #TranslationalImmunology that took place in May in #Monopoly, Italy🌟 🔬
🌟🔬 🌟 🔬 Just got back from the 6th SIICA International Conference of Translational Immunology in beautiful Monopoli! 🌅 Had a blast presenting my research poster and soaking up all the amazing talks. Met so many awesome people and even picked up some unscientific skills, like dancing the pizzica pugliese! 🕺🕺 🙏Big thanks to everyone who made it such a fantastic event! 🙏 #SIICA2024 #TranslationalImmunology #CAPSTONE_H2020 #MSCA
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🚀 Highlight 6: Dario Guglietta (ESR6) from the University of Southampton presented his research work at the 2024 Congress of the European Association for Cancer Research (EACR) research, #EACR2024, this past June in #Rotterdam🌟
PhD in cancer immunology and antigen presentation, funded by CAPSTONE ITN, Marie Skłodowska-Curie doctoral network
II am glad to have had the opportunity to present my research at #EACR2024 and interact with the international oncology research community. It was inspiring to see how much our knowledge is advancing and how many different strategies are being used across the globe to beat cancers. Many thanks to European Association for Cancer Research (EACR) for organising this event.
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🚀 Highlight 5: Adele-Asia Ponzoni (ESR13) from Aliri Bioanalysis participated at this year's American Society For Mass Spectrometry (ASMS) conference in #Anaheim, #California! 🌟
Come meet Adele-Asia Ponzoni at MP 078 to learn how we are working to provide a novel view on whole-body #biodistribution. #Aliri #ASMS
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🚀 Highlight 4: Kamila Król's secondment in the team of Dr Efstratios Stratikos at NCSR Demokritos and at the University of Athens with ESR4 Martha Nikopaschou!🌟
👩🔬👩🔬👩🔬 Over the past two weeks, I had the opportunity to work at the University of Athens as part of my secondment with CAPSTONE_H2020. My research during that time focused on investigating the influence of ERAP1 on the immunopeptidome of leukemia cells. I am grateful to have had the guidance and support of experts in the field, Efstratios Stratikos and ESR4 Martha Nikopaschou, whose assistance was invaluable in conducting experiments and advancing my research. 👩🔬👩🔬👩🔬 #capstone #h2020 #esr #immunopeptidome #leukemia #immunotherapy
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🚀 Highlight 3: Shami Álvarez attending th 2024 American Association for Cancer Research Conference in San Diego🌟
Happy to share that I presented a poster with the results of my PhD project in the American Association for Cancer Research Conference in San Diego, California. The AACR brings together experts in cancer research from all over the world for a week packed of workshops, exhibitions and symposiums of the latest breakthroughs in cancer sciences. This was a great opportunity to hear about all the cutting edge research that is taking place across the world to fight cancer and a very encouraging experience to keep advacing our research. #AACR2024 #CancerResearch #CAPSTONE
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🚀 Highlight 2: Paula Gragera's secondment at National Center for Scientific Research "Demokritos"🌟
🌟 After two great months in Athens, I would like to thank Martha Nikopaschou and Prof. Efstratios Stratikos from the National Center for Scientific Research "Demokritos" for their invaluable mentorship and guidance during my secondment in immunopeptidomics as part of my training as a CAPSTONE_H2020 Early-Stage Researcher. 🧬🔬 Also many thanks to the other lab members Dr. Anastasia Mpakali, Galateia Georgaki. I'm grateful for the opportunity to collaborate with such esteemed professionals. This experience has not only enriched my academic journey but has also inspired me to aim for excellence in my future objectives. Thank you for your generosity, encouragement, and unwavering support. I look forward to continuing our collaboration and contributing to the advancement of our research together. 🚀🔍 #Immunopeptidomics #Research #DemokritosResearchInstitute #CAPSTONE_H2020 #Collaboration
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📚 As we are approaching the end of the academic year, we would like to share with you some highlights of our ESRs. 🚀 Highlight 1: Kamila Król's secondment at Cellply🌟 #capstone #capstonecommunity #msca #h2020 #secondment #esr #immunology #singlecellanalysis #nk #immunotherapy
We would like to thank Kamila Król for her 6 weeks of secondment in our Team. 👩🏼🔬 🔬 During this period Kamila used our VivaCyte® platform to 𝐩𝐞𝐫𝐟𝐨𝐫𝐦 𝐬𝐢𝐧𝐠𝐥𝐞 𝐜𝐞𝐥𝐥 𝐚𝐧𝐚𝐥𝐲𝐬𝐢𝐬 𝐭𝐨 𝐛𝐞𝐭𝐭𝐞𝐫 𝐮𝐧𝐝𝐞𝐫𝐬𝐭𝐚𝐧𝐝 𝐭𝐡𝐞 𝐫𝐨𝐥𝐞 𝐨𝐟 𝐄𝐫𝐚𝐩𝟏 𝐢𝐧 𝐜𝐚𝐧𝐜𝐞𝐫 𝐢𝐦𝐦𝐮𝐧𝐞 𝐫𝐞𝐬𝐩𝐨𝐧𝐬𝐞 𝐦𝐞𝐝𝐢𝐚𝐭𝐞𝐝 𝐛𝐲 𝐍𝐊 𝐜𝐞𝐥𝐥𝐬. A special thank also to Ospedale Pediatrico Bambino Gesù and CAPSTONE_H2020. Discover the full potential of our platform ➡️https://lnkd.in/dUMpxXTw #msca #Horizon2020 #CapstoneProject #CellTherapy #NKcells
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🌟Exciting news from CAPSTONE_H2020! A new paper from our early stage #researchers: Vasileios Fougiaxis, Ben He and Nikoletta Koutroumpa is published👇 Read a full paper: https://lnkd.in/ew8EzhKB #MSCA #research #collaboration
After almost 2 years of work, my co-authors and I are very proud to announce the publication of our Perspective paper on ERAP inhibitors in the Journal of Medicinal Chemistry #deprezlab CAPSTONE_H2020 Vasileios Fougiaxis, Ben He & Nikoletta Koutroumpa, are PhD students from the MSCA CAPSTONE consortium