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Genetics news
Oncology & Cancer
Researchers learn how cancer cells divide despite treatment
Researchers in the lab of Jean Cook, Ph.D., chair and professor in the Department of Biochemistry and Biophysics, have identified the cellular processes that occur when you take a cancer drug meant to stop rapid cell growth ...
Jul 19, 2024
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Genetics
Understanding molecular drivers of lymphedema
Northwestern Medicine scientists have uncovered molecular mechanisms underlying lymphatic valve development, a discovery which could prove useful in treating lymphedema, according to a study published in the Journal of Clinical ...
Jul 19, 2024
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Study unravels clinical, genomic characteristics of non-tuberculous mycobacteria in Europe
A multinational European study provides the first comprehensive clinical and genomic data on the Mycobacterium avium complex from continental Europe. The data reveal the population structure of this group of pathogens and ...
Jul 19, 2024
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Genetic study highlights importance of diversity in understanding health disparities
The majority of genetic studies focus on people of European descent, which limits the understanding of how genes influence health in other populations. Now researchers at the Perelman School of Medicine at the University ...
Jul 18, 2024
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Researchers develop new technique for diagnosing disorders of sex development
Disorders/differences of sex development (DSD) are difficult to diagnose because of the multiple phenotypes and genes involved, but a new technique developed at Hudson Institute of Medical Research is set to change all that.
Jul 18, 2024
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Findings reveal unexpected role of protein OTX2 that drives aggressive medulloblastoma
In a report published in Nature Cell Biology, researchers at Baylor College of Medicine, Texas Children's Hospital, the University of Manitoba and collaborating institutions have revealed an unexpected way in which the protein ...
Jul 18, 2024
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![](https://scx1.b-cdn.net/csz/news/175u/2022/brain-cancer.jpg)
Subretinal adeno-associated virus T-cell inhibition: Exploring potential existence of anti-transgene immune responses
A new study shows that subretinal adeno-associated virus 8 (AAV8) injections cause proinflammatory T-cell immune response against the transgene product. According to the study, published in the journal Human Gene Therapy, ...
Jul 18, 2024
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![](https://scx1.b-cdn.net/csz/news/175u/2024/subretinal-aav-t-cell.jpg)
New gene therapy for muscular dystrophy offers hope
A new gene therapy treatment for Duchenne muscular dystrophy shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those ...
Jul 17, 2024
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![](https://scx1.b-cdn.net/csz/news/175u/2024/new-gene-therapy-for-m-1.jpg)
Study addresses a long-standing diversity bias in human genetics
Most research in human genetics has historically focused on people of European ancestries—a long-standing bias that may limit the accuracy of scientific predictions for people from other populations.
Jul 17, 2024
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Distinct signaling pathway identified as key driver for epithelial cancer development
A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF-α program and become invasive. This finding could ...
Jul 17, 2024
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Boost in infant genetics research could change lives, say researchers
Investment in research into genetics could dramatically improve educational policies and understanding of parenting in ways that could help all children, according to a new paper led by the University of Surrey.
Jul 17, 2024
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New NIPT-based method reveals 33 pathogenic copy number variations in the Duchenne muscular dystrophy gene
A recent large cohort study, conducted jointly by researchers from BGI Genomics and Nanjing Women and Children's Healthcare Hospital, implemented a self-developed prenatal screening strategy to effectively identify and classify ...
Jul 17, 2024
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![](https://scx1.b-cdn.net/csz/news/175u/2024/new-nipt-based-method-1.jpg)
Study uncovers genetic cancer risks in 550 patients
Current screening protocols fail to catch a notable number of people carrying genetic mutations associated with hereditary breast and ovarian cancer syndrome and Lynch syndrome, which increase the risk of developing certain ...
Jul 17, 2024
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![](https://scx1.b-cdn.net/csz/news/175u/2019/1-genetic.jpg)
Study reveals secrets of energy metabolism, promising better blood transfusions
Researchers at the University of Colorado School of Medicine have uncovered insights into how red blood cells function and survive during storage—discoveries that could lead to better outcomes for patients receiving blood ...
Jul 16, 2024
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![](https://scx1.b-cdn.net/csz/news/175u/2024/study-reveals-secrets.jpg)
Team explores strategies for correcting mutations that cause stroke
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is a rare, severe, and deadly genetic disorder characterized by damage to small blood vessels in the brain. The condition ...
Jul 16, 2024
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Novel protein detects and responds to changes in blood flow
When blood moves through your body, it exerts a frictional force on the walls of blood vessels. This force, known as fluid shear stress, has important effects on vascular development, function, and disease.
Jul 16, 2024
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![](https://scx1.b-cdn.net/csz/news/175u/2024/novel-protein-detects.jpg)
Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells
Individual cells in the human body develop progressively over time, ultimately becoming specialized in specific functions. This process, known as cell differentiation or specialization, is central to the formation of distinct ...
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Preclinical data suggest antioxidant strategy to address mitochondrial dysfunction caused by SARS-CoV-2 virus
Building upon groundbreaking research demonstrating how the SARS-CoV-2 virus disrupts mitochondrial function in multiple organs, researchers from Children's Hospital of Philadelphia (CHOP) demonstrated that mitochondrially-targeted ...
Jul 15, 2024
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![](https://scx1.b-cdn.net/csz/news/175u/2022/sars-cov-2-1.jpg)
How a gene for obesity affects the brain
Obesity is a complicated condition, caused by a combination of genetics, the food environment, behavior, and other factors. For millennia, getting enough food to survive and thrive was difficult. For most people, it's now ...
Jul 15, 2024
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![](https://scx1.b-cdn.net/csz/news/175u/2024/how-a-gene-for-obesity-1.jpg)
Study reveals gene 'switched off' in early stages of pancreatic cancer allows rapid tumor growth and spread
Scientists at Nottingham Trent University, the University of Nottingham, Stanford University and the University of California and Cedars-Sinai Medical Center, Los Angeles, have found that the molecule "HNF4A" suppresses pancreatic ...
Jul 15, 2024
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