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Alabama vs. North Carolina odds, prediction: March Madness Sweet 16 picks

Even as a No. 1 seed, North Carolina seems a tad undervalued heading into its Sweet 16 matchup Thursday night with Alabama (9:39 p.m. ET, CBS).

The Tar Heels are the worst among the NCAA Tournament’s four top seeds, but they’re not as far behind the others as the public believes. 

Let’s take a look at this fun matchup that oddsmakers project will be the highest-scoring of the eight Sweet 16 games over the next two days.

Alabama vs. North Carolina odds

SpreadTotalMoneyline
Alabama +4.5 (-110)Over 173.5 (-110)Alabama +158
North Carolina -4.5 (-110)Under 173.5 (-110)North Carolina -192
Odds via FanDuel

Alabama vs. North Carolina analysis

RJ Davis is a madman with middle-of-the-floor dribble and shot creation that no one in college basketball duplicates.

Armando Bacot is still among the nation’s best post-up players and rebounders.

Elliot Cadeau has improved all year.

Cormac Ryan and Harrison Ingram are vital cogs on the wing. 

The Heels play great interior defense, ranking top-25 nationally in two-point shooting allowed and paint points per game allowed, while rebounding everything. 

Elliot Cadeau #2 of the North Carolina Tar Heels celebrates during the game against the North Carolina State Wolfpack in the Championship Game of the ACC Men's Basketball Tournament.
Elliot Cadeau #2 of the North Carolina Tar Heels celebrates during the game against the North Carolina State Wolfpack in the Championship Game of the ACC Tournament. Getty Images

North Carolina might struggle with Alabama’s elite off-ball secondary and isolation actions, but you can only hope to contain the Tide, who averaged 90.8 points per game in the regular season. 

The Heels have a shot at containment, given that they have the nation’s best transition denial defense and the fourth-best rim-and-3 defense by PPP allowed.

Both will be monstrous against Nate Oats’ offense, which emphasizes up-tempo, rim-and-3 basketball. 

Conversely, North Carolina should be able to score on a high percentage of its possessions. 


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The Tide run a drop-coverage defense with limited rim protection and rebounding.

The first issue is vulnerable to Davis’ on-ball dribble- and middle-of-the-floor creation, and the latter two are vulnerable to Bacot’s post-creation and offensive rebounding. 

Not to mention Alabama fouls like crazy, while North Carolina draws fouls at a top-80 rate nationally. 

Alabama vs. North Carolina pick

The Heels should score at will, and their defense is sturdy enough to generate enough tough stops to cover the two-possession spread, earning UNC another trip to the Elite Eight. 

Pick: North Carolina -4.5 (-110, FanDuel)