Patricia Arquette's 2 Children: All About Harlow and Enzo

Patricia Arquette’s children, Enzo Rossi and Harlow Jane, have helped make her into the actress she is today.

The Academy Award winner shares Enzo, born in 1989, with her ex-boyfriend, Argentinian musician Paul Rossi. They split up amicably when Enzo was 1 month old.

During the filming of Boyhood, which took place over 12 years, Arquette welcomed daughter Harlow in 2003 with her then-partner, actor Thomas Jane. Arquette and Jane wed in 2006 and split up in 2009 before reconciling that same year, ultimately calling it quits in 2010.

Harlow has followed in her parents’ footsteps, acting in a handful of projects, including Apple TV+'s High Desert as a younger version of Arquette's character and joining her father in the thriller Dig. But Hollywood wasn't Harlow’s original dream.

“I did not want to become another actor,” Harlow told PEOPLE in 2023. “But I couldn't help but secretly love it.”

Though Arquette has played many roles over the years, she feels her most important one is mom.

"The healthy order of things is your children have the most needs, especially when they're little, and you're supposed to deal with their needs. It's not about you," she told PEOPLE in 2024. "And as you get older, yes, you kind of push them a little more to stand on their own and question things and treat you well, because it teaches them to treat other people outside well. But it's still not really about you.”

Here’s everything to know about Patricia Arquette's children, Harlow and Enzo.

Enzo Rossi, 35

Arquette welcomed son Enzo with then-boyfriend Rossi, an Argentinian musician, in Los Angeles on Jan. 3, 1989.

The Gonzo Girl director and Rossi split amicably when Enzo was 1 month old and remained close.  "We were wrong for each other," Arquette told The New York Times in 1993 of her ex. "But when I got pregnant, I knew this person needed to be born."

The Severance star told the outlet that at the time, the longest she and Enzo, who grew up in L.A.’s Hollywood Hills, were apart was seven days, and she wore a ring set of her son's birthstone, garnet, to the premiere if her 1993 film, True Romance.

“I’m not a great disciplinarian. But luckily Enzo didn’t really need that. I just talked him through things,” Arquette told USA Weekend in 2005. “[My brother] David [Arquette] helped me a lot with understanding him.”

Having Enzo at a young age informed Arquette's career, motivating her to continue to go on auditions, and later helped her prepare for her role in Boyhood.

"The pressure lit such a fire under my a--: ‘I have to make money. I have to succeed. I have to provide for somebody.’ Even though I’d done a few acting jobs, I had no money, and I wasn’t getting anything. It was all so hard to manage," she told The New Yorker in 2022, noting she got a waitressing job but “walked away” from it days later when she landed a role in Bad Influence.

Enzo has appeared in a handful of his mother's projects, including 1991's The Indian Runner, True Romance and 1996's Beyond Rangoon. He also acted in a 2009 episode of her supernatural show, Medium, playing a character Arquette described to TV Guide as “an egg-headed, scientific kid.”

Enzo nabbed the role because Arquette was directing the episode and had trouble casting the part, so she called her son the night before and told him, "You have to do this for me,” she told The Futon Critic in 2009.

Enzo went off to college around the same time Arquette filmed a scene for Boyhood, where her character cried while packing her son up to leave for school.

“I felt very similar to that [character] — that life was just flying by, and my son was taking off and beginning to live an independent life, and there are a lot of emotions surrounding that. Then you get the call a couple weeks later, ‘Mom, where do I get socks?’ ” she recalled to AARP in 2019. “I'm like, Oh, I'm still a mom. It didn't really stop, okay.”

Enzo has made a couple of red carpet appearances, joining his mom and her then-husband, Jane, for the 2004 premiere of his film The Punisher, and his mom and her brother David for the opening night of Sir Arthur Conan Doyle’s Sherlock Holmes in 2015.

Along with other partners, Arquette and Enzo collaborated on Fantom Flower, a cannabis lounge in West Hollywood. It started construction in 2022, according to Vanity Fair, but according to their website, it is still coming soon.

Harlow Olivia Calliope Jane, 21

Born at home in L.A. on Feb. 20, 2003, Harlow Olivia Calliope Jane is the only child of Arquette and her ex-husband, Jane.

The pair met through mutual friends in 2001 and wed in Italy in May 2006. The Otherhood actress initially filed for divorce in January 2009, before she withdrew the divorce petition in July. The couple then split for good in August 2010.

Their daughter went to a “very arts-heavy boarding school” in her teens, which is when she realized she wanted to become an actress. Following in her parents' footsteps, however, wasn't always the plan. Harlow said she was bored on sets when she was younger, because “whatever your parent does ... it’s not exciting. But she did note that she loved hanging out with her mom in the makeup trailer and “watching the director work.”

“I definitely rebelled against it for as long as I could,” Harlow told PEOPLE. “I remember in first or second grade, we had a career person come to school and I told them that I wanted to be a lawyer.”

Harlow acted in the 2015 miniseries Texas Rising, 2021's I Love Us and 2023's She Came to Me. However, she called Dig, the 2022 action thriller she starred in with her father and learned American Sign Language for, her “first real job” in a 2022 interview with ScreenRant. She also played a younger version of Arquette's character, Peggy, in one episode of High Desert.

“I love my mom, and I just felt like I knew what her face would look like in this moment of screaming at someone,” she told PEOPLE in 2023.

Harlow has walked many red carpets with her famous parents, including joining Arquette at the 2015 Oscars, the 2019 Golden Globe Awards and the 2024 Vanity Fair Oscar Party, and Jane at the 2022 premiere of Murder at Yellowstone City. Both of her parents were by Harlow’s side at the 2023 screening of her film, She Came to Me, in L.A.

Though she's worked with her mom, Harlow told PEOPLE in 2024 that she doesn't watch Arquette's movies, only “clips” here and there.

"The magic of it isn't there because she's just always been Mom, so I just can't see you as anything other than my mom," Harlow told Arquette.

"And I don't ever want you to see me as anything other than your mom, honestly," The Act star responded. "I don't act for validation. I'm grateful for all the success that I've had, but I want to be me authentically, and the only two people in this world that I'm really mom to are you and your brother."

Harlow now considers herself “lucky" to have grown up around "eccentric" creatives.

“I think people who are artists and creative, we're pretty prone to our big emotions,” she told PEOPLE. “But also, it was beautiful. It was great. I'm lucky to have grown up around so much art and creation and creativity. It was a general spirit of playfulness, even today.”