Jose Peralta

Large molecule proteins if hydrolyze by enzymes, will produce low molecular protein hydrolysates; peptides and amino acids. As food, they become easily digestible and assimilated by the human body.
Chemotherapy has a wide range of side effects that can affect the patients’ quality of life. This may include chemo-induced dermatitis, xerostomia (dry-mouth) and cachexia (loss of skeletal muscle mass). The lack of appetite during chemo treatments also contributes to poor nutrition and leads… Mas marami pa

Large molecule proteins if hydrolyze by enzymes, will produce low molecular protein hydrolysates; peptides and amino acids. As food, they become easily digestible and assimilated by the human body.
Chemotherapy has a wide range of side effects that can affect the patients’ quality of life. This may include chemo-induced dermatitis, xerostomia (dry-mouth) and cachexia (loss of skeletal muscle mass). The lack of appetite during chemo treatments also contributes to poor nutrition and leads to immune-compromised patients. In addition to cancer patients, post-surgery patients, persons with health dysfunctions, & etc. are also target users. Protein hydrolysates are used for the nutritional management of individuals who cannot digest intact protein. These provide sufficient nutrition for health maintenance of health impaired individuals (Silvestre, 1997).
Furthermore, the resulting low molecular bioactive peptides have shown a lot of physiological activities; to include anti-oxidant, anti-bacterial, antimicrobial, anti-oxidants, anti-diabetes, antihypertensive (ACE) inhibition, anticoagulant and anticancer properties and more. (Ao and Li, 2011, Chang-Feng et al., 2015, and etc. They are also responsible for the regulation and modulation of the body metabolism; including the immune responses.
In the Philippines, only a few studies on hydrolysates are being conducted. This is somehow hindered by the lack of facilities, pool of experts, and funding support by the government and other funding agencies. However, the country is rich in aquatic marine resources, which are yet to be explored in terms of their properties and characteristics for potential application in human nutrition and pharmaceuticals.
For now, our Proj Team is focused on having these products as nutraceuticals, food ingredients, and feed ingredients. Eventually, research will focus on development of pharmaceutical products. Mas kaunti

The marine resources offers a vast options of protein sources. Proteins if hydrolyzed by enzymes will produce hydrolysates. These protein hydrolysate offers a vast functional characteristics intended as food supplements for sick people (or people with low immune responses). The food protein needed should be easy to digest, provides complete nutrition, and would complement sickness healing (and/or increase the immune system responses).

The available food supplements in the market have… Mas marami pa

The marine resources offers a vast options of protein sources. Proteins if hydrolyzed by enzymes will produce hydrolysates. These protein hydrolysate offers a vast functional characteristics intended as food supplements for sick people (or people with low immune responses). The food protein needed should be easy to digest, provides complete nutrition, and would complement sickness healing (and/or increase the immune system responses).

The available food supplements in the market have similar characteristics. From Nestle; we have Peptamen and Nutrient Optimum. From Brands, we have Essence of Chicken. These food supplements or food formulations are basically hydrolysates or peptides; rich in essential amino acids.
The Project is partnering with Pascual Pharma Corp., a Philippine drug company, who will be the end user of the products that will be developed. The current USAID-STRIDE project is limited to year one.

The project is proposing a hypotheses that sick people (or those with impaired immune system); should have their body functions and metabolism focus, divert most of its energy, in addressing and repairing what is wrong with the body. Given the opportunity, the human body could heal and repair itself. In line with this thought, the body should not spend so much energy in the process of digestion. This could be done by the provision of simple, easy to digest foods of complete nutrition, and with minimum metabolic energy load, in the form of peptides. Further, literature suggests that the components of hydrolysates; the peptides, if they are in its smallest molecular structure (peptide, di-peptides or tri-peptides), also become bio-active compounds, that assist and facilitate body functions and metabolisms. Mas kaunti