Muscular Dystrophy, Duchenne
"Muscular Dystrophy, Duchenne" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
| Descriptor ID |
D020388
|
| MeSH Number(s) |
C05.651.534.500.300 C10.668.491.175.500.300 C16.320.322.562 C16.320.577.300
|
| Concept/Terms |
Muscular Dystrophy, Duchenne- Muscular Dystrophy, Duchenne
- Cardiomyopathy, Dilated, X-Linked
- Childhood Muscular Dystrophy, Pseudohypertrophic
- Childhood Pseudohypertrophic Muscular Dystrophy
- Duchenne Muscular Dystrophy
- Duchenne-Type Progressive Muscular Dystrophy
- Duchenne Type Progressive Muscular Dystrophy
- Muscular Dystrophy, Childhood, Pseudohypertrophic
- Muscular Dystrophy, Duchenne Type
- Muscular Dystrophy, Pseudohypertrophic
- Pseudohypertrophic Muscular Dystrophy
- Muscular Dystrophy, Pseudohypertrophic Progressive, Duchenne Type
- Muscular Dystrophy, Pseudohypertrophic, Childhood
- Progressive Muscular Dystrophy, Duchenne Type
- Pseudohypertrophic Childhood Muscular Dystrophy
- Pseudohypertrophic Muscular Dystrophy, Childhood
- Cardiomyopathy, Dilated, 3B
Duchenne and Becker Muscular Dystrophy- Duchenne and Becker Muscular Dystrophy
- Muscular Dystrophy, Duchenne and Becker Types
- Duchenne-Becker Muscular Dystrophy
- Duchenne Becker Muscular Dystrophy
- Muscular Dystrophy, Duchenne-Becker
Becker Muscular Dystrophy- Becker Muscular Dystrophy
- Muscular Dystrophy, Pseudohypertrophic Progressive, Becker Type
- Muscular Dystrophy, Becker
- Muscular Dystrophy, Becker Type
- Becker's Muscular Dystrophy
- Muscular Dystrophy, Becker's
- Muscular Dystrophy Pseudohypertrophic Progressive, Becker Type
|
Below are MeSH descriptors whose meaning is more general than "Muscular Dystrophy, Duchenne".
- Diseases [C]
- Musculoskeletal Diseases [C05]
- Muscular Diseases [C05.651]
- Muscular Disorders, Atrophic [C05.651.534]
- Muscular Dystrophies [C05.651.534.500]
- Muscular Dystrophy, Duchenne [C05.651.534.500.300]
- Nervous System Diseases [C10]
- Neuromuscular Diseases [C10.668]
- Muscular Diseases [C10.668.491]
- Muscular Disorders, Atrophic [C10.668.491.175]
- Muscular Dystrophies [C10.668.491.175.500]
- Muscular Dystrophy, Duchenne [C10.668.491.175.500.300]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Genetic Diseases, X-Linked [C16.320.322]
- Muscular Dystrophy, Duchenne [C16.320.322.562]
- Muscular Dystrophies [C16.320.577]
- Muscular Dystrophy, Duchenne [C16.320.577.300]
Below are MeSH descriptors whose meaning is more specific than "Muscular Dystrophy, Duchenne".
This graph shows the total number of publications written about "Muscular Dystrophy, Duchenne" by people in this website by year, and whether "Muscular Dystrophy, Duchenne" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 4 | 0 | 4 |
| 2001 | 2 | 1 | 3 |
| 2002 | 4 | 1 | 5 |
| 2003 | 5 | 1 | 6 |
| 2004 | 2 | 2 | 4 |
| 2005 | 7 | 0 | 7 |
| 2006 | 5 | 1 | 6 |
| 2007 | 4 | 0 | 4 |
| 2008 | 7 | 1 | 8 |
| 2009 | 9 | 0 | 9 |
| 2010 | 16 | 0 | 16 |
| 2011 | 9 | 1 | 10 |
| 2012 | 8 | 3 | 11 |
| 2013 | 10 | 4 | 14 |
| 2014 | 17 | 3 | 20 |
| 2015 | 18 | 1 | 19 |
| 2016 | 17 | 2 | 19 |
| 2017 | 17 | 1 | 18 |
| 2018 | 20 | 0 | 20 |
| 2019 | 17 | 3 | 20 |
| 2020 | 29 | 1 | 30 |
| 2021 | 23 | 4 | 27 |
| 2022 | 35 | 0 | 35 |
| 2023 | 18 | 0 | 18 |
| 2024 | 17 | 1 | 18 |
Below are the most recent publications written about "Muscular Dystrophy, Duchenne" by people in Profiles.
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Benfotiamine improves dystrophic pathology and exercise capacity in mdx mice by reducing inflammation and fibrosis. Hum Mol Genet. 2024 Jul 22; 33(15):1339-1355.
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Meaningful changes in motor function in Duchenne muscular dystrophy (DMD): A multi-center study. PLoS One. 2024; 19(7):e0304984.
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Eteplirsen Treatment for Duchenne Muscular Dystrophy: A Qualitative Patient Experience Study. Adv Ther. 2024 Aug; 41(8):3278-3298.
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Quantifying the insurance value for rare diseases: Duchenne muscular dystrophy. Am J Manag Care. 2024 07 01; 30(7):e217-e222.
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Functional trajectories before and after loss of ambulation in Duchenne muscular dystrophy and implications for clinical trials. PLoS One. 2024; 19(6):e0304099.
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The Development of Robust Antibodies to Sarcospan, a Dystrophin- and Integrin-Associated Protein, for Basic and Translational Research. Int J Mol Sci. 2024 Jun 01; 25(11).
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Factors Associated With Early Motor Function Trajectories in DMD After Glucocorticoid Initiation: Post Hoc Analysis of the FOR-DMD Trial. Neurology. 2024 May 28; 102(10):e209206.
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Safety and efficacy of givinostat in boys with Duchenne muscular dystrophy (EPIDYS): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Neurol. 2024 Apr; 23(4):393-403.
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MCU-independent Ca2+ uptake mediates mitochondrial Ca2+ overload and necrotic cell death in a mouse model of Duchenne muscular dystrophy. Sci Rep. 2024 03 21; 14(1):6751.
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Survival among patients receiving eteplirsen for up to 8 years for the treatment of Duchenne muscular dystrophy and contextualization with natural history controls. Muscle Nerve. 2024 Jul; 70(1):60-70.