High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis

Br J Sports Med. 2014 Aug;48(16):1227-34. doi: 10.1136/bjsports-2013-092576. Epub 2013 Oct 21.

Abstract

Background/aim: Cardiorespiratory fitness (CRF) is a strong determinant of morbidity and mortality. In athletes and the general population, it is established that high-intensity interval training (HIIT) is superior to moderate-intensity continuous training (MICT) in improving CRF. This is a systematic review and meta-analysis to quantify the efficacy and safety of HIIT compared to MICT in individuals with chronic cardiometabolic lifestyle diseases.

Methods: The included studies were required to have a population sample of chronic disease, where poor lifestyle is considered as a main contributor to the disease. The procedural quality of the studies was assessed by use of a modified Physiotherapy Evidence Base Database (PEDro) scale. A meta-analysis compared the mean difference (MD) of preintervention versus postintervention CRF (VO2peak) between HIIT and MICT.

Results: 10 studies with 273 patients were included in the meta-analysis. Participants had coronary artery disease, heart failure, hypertension, metabolic syndrome and obesity. There was a significantly higher increase in the VO2peak after HIIT compared to MICT (MD 3.03 mL/kg/min, 95% CI 2.00 to 4.07), equivalent to 9.1%.

Conclusions: HIIT significantly increases CRF by almost double that of MICT in patients with lifestyle-induced chronic diseases.

Keywords: Aerobic Fitness/Vo2 Max; Cardiovascular; Exercise Physiology; Statistical Review.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Antioxidants / metabolism
  • Cardiac Rehabilitation*
  • Chronic Disease
  • Exercise Therapy / methods*
  • Humans
  • Life Style
  • Metabolic Diseases / rehabilitation*
  • Oxygen Consumption / physiology
  • Patient Compliance
  • Quality of Life
  • Risk Factors
  • Treatment Outcome

Substances

  • Antioxidants