Oxide semiconductor thin‐film transistors: a review of recent advances
Transparent electronics is today one of the most advanced topics for a wide range of device
applications. The key components are wide bandgap semiconductors, where oxides of …
applications. The key components are wide bandgap semiconductors, where oxides of …
Non–small cell lung cancer
Lung cancer is the leading cause of cancer-related death in the United States. An estimated
219,440 new cases (116,090 men; 103,350 women) of lung and bronchus cancer were …
219,440 new cases (116,090 men; 103,350 women) of lung and bronchus cancer were …
Long live FOXO: unraveling the role of FOXO proteins in aging and longevity
Aging constitutes the key risk factor for age‐related diseases such as cancer and
cardiovascular and neurodegenerative disorders. Human longevity and healthy aging are …
cardiovascular and neurodegenerative disorders. Human longevity and healthy aging are …
Safety and activity of anti–PD-L1 antibody in patients with advanced cancer
…, HC Pitot, O Hamid, S Bhatia, R Martins… - … England Journal of …, 2012 - Mass Medical Soc
Background Programmed death 1 (PD-1) protein, a T-cell coinhibitory receptor, and one of
its ligands, PD-L1, play a pivotal role in the ability of tumor cells to evade the host's immune …
its ligands, PD-L1, play a pivotal role in the ability of tumor cells to evade the host's immune …
Clinical and biomarker changes in dominantly inherited Alzheimer's disease
RJ Bateman, C Xiong, TLS Benzinger… - … England Journal of …, 2012 - Mass Medical Soc
Background The order and magnitude of pathologic processes in Alzheimer's disease are
not well understood, partly because the disease develops over many years. Autosomal …
not well understood, partly because the disease develops over many years. Autosomal …
[HTML][HTML] Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients
TS Rodrigues, KSG de Sá, AY Ishimoto… - Journal of Experimental …, 2021 - rupress.org
Severe cases of COVID-19 are characterized by a strong inflammatory process that may
ultimately lead to organ failure and patient death. The NLRP3 inflammasome is a molecular …
ultimately lead to organ failure and patient death. The NLRP3 inflammasome is a molecular …
Erlotinib in previously treated non–small-cell lung cancer
…, S Maoleekoonpiroj, M Smylie, R Martins… - New England journal …, 2005 - Mass Medical Soc
Background We conducted a randomized, placebo-controlled, double-blind trial to
determine whether the epidermal growth factor receptor inhibitor erlotinib prolongs survival …
determine whether the epidermal growth factor receptor inhibitor erlotinib prolongs survival …
Non–small cell lung cancer, version 5.2017, NCCN clinical practice guidelines in oncology
This selection from the NCCN Guidelines for Non–Small Cell Lung Cancer (NSCLC)
focuses on targeted therapies and immunotherapies for metastatic NSCLC, because …
focuses on targeted therapies and immunotherapies for metastatic NSCLC, because …
Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label …
CJ Langer, SM Gadgeel, H Borghaei… - The lancet …, 2016 - thelancet.com
Background Limited evidence exists to show that adding a third agent to platinum-doublet
chemotherapy improves efficacy in the first-line advanced non-small-cell lung cancer …
chemotherapy improves efficacy in the first-line advanced non-small-cell lung cancer …
SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology
Severe COVID-19 patients develop acute respiratory distress syndrome that may progress to
cytokine storm syndrome, organ dysfunction, and death. Considering that neutrophil …
cytokine storm syndrome, organ dysfunction, and death. Considering that neutrophil …