Revolutionizing Gene Therapies and Vaccines: Discover 4basebio's innovation in action. Watch our video to learn how we are harnessing our novel synthetic DNA technology and non-viral, targeting delivery platform to accelerate the development of advanced therapy medicinal products (ATMPs). Learn more on www.4basebio.com. #GeneTherapies #Vaccines #biotechnology #Innovation #4bbDNA #ATMP
About us
4basebio is enabling next generation cell and gene therapies and vaccines with its technologies and solutions. We are able to design, manufacture and supply application-specific synthetic DNA or mRNA as well as targeted non-viral vectors for the delivery of nucleic acid payloads. Our novel synthetic DNA technology offers unique customisation potential, rapid turn-around times, and improved safety profiles, addressing the current limitations of plasmids and other DNA technologies. We currently offer four DNA construct types, each ideally suited for use in viral and non-viral vector applications, genome editing, vaccines and therapeutics, and DNA vaccine applications, respectively. Our proprietary non-viral delivery system, Hermes™, is a nanoparticle vector that can be customised to target cells or tissues of interest for a range of applications. This combines the safety and efficiency of lipid-based nanoparticles (LNPs) with the specificity of a targeting system, addressing the shortcoming associated with both viral vectors and non-targeted LNPs.
- Website
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https://www.4basebio.com/
External link for 4basebio
- Industry
- Biotechnology
- Company size
- 11-50 employees
- Headquarters
- Cambridge
- Type
- Public Company
Locations
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Primary
25 Norman Way
Over
Cambridge, CB245QE, GB
Employees at 4basebio
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Bertrand Coissac
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Deborah Day Barbara
Transformational growth is not difficult if you prioritize your customers, participate in growth markets, deliver customer centered innovation and…
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Larry Pitcher
Vice President and General Manager, Maryland Gene Therapy CDMO Sites at Catalent
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Céline Winckler
Experienced Scientist with versatile skills
Updates
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Join us this week at RNA Leaders USA, from 4-5th September in San Diego! Connect with Heikki Lanckriet, CEO and Amy Walker, COO who will be there to connect and showcase our posters on: • Production of In Vitro Transcribed mRNA Using Synthetic, Enzymatically Produced Linear DNA • Synthetic Enzymatically Produced DNA for Gene Therapy and Vaccine Applications Make sure not to miss Amy’s presentation held on the 4th of September at 2:10pm-2:35pm, where she will delve into the production of 𝘪𝘯 𝘷𝘪𝘵𝘳𝘰 transcribed mRNA using synthetic, enzymatically produced linear DNA and how it can overcome many of the bottlenecks associated with plasmid DNA. If you would like to meet, drop us a message through the Partnering One app! #syntheticDNA #mRNA #therapeutics #vaccines #RNALeaders
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4basebio took part in a sunflower growing competition in honour of World Earth Day this year 🌍🌿 Congratulations to our 2 winners: Caitlyn Bruce from our Norman Way site and Ben Tilley Tilly from our Buckingway site! Let's just say it was a close competition!😂
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4basebio is excited to be back again this year at the 16th Annual Bioprocessing Summit in Boston, August 19-22nd! Connect with Florent Fordoxel, our Business Development Associate Director who will be there to connect and showcase our poster on: ‘Production of AAV Vectors Using Synthetic, Enzymatically Produced Linear DNA’ See you there! #AAV #CHIBioprocessingSummit #SyntheticDNA
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4basebio is very pleased to announce the formation of a Strategic Advisory Board (“SAB”) to support the Company’s ambitious growth goals and objectives. We welcome Bertrand Coissac, Lawrence Pitcher and Deborah Barbara to our SAB, each of whom will contribute invaluable insight and advice across technical, operational, commercial and strategic matters. In addition, 4basebio is also delighted to announce the appointment of Dr. Amy Walker to the board of directors as Chief Operating Officer for the company. Amy joined 4basebio in 2020 and has been instrumental in both its technological development and commercial growth and we congratulate her on this appointment. https://lnkd.in/ezcqmPU3 Bertrand Coissac Larry Pitcher Deborah Day Barbara Amy Walker #thefutureissynthetic #4basebio
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We are delighted to announce 4basebio has agreed binding terms with (i) Elevage Medical Technologies ("Elevage"), a Patient Square Capital platform and (ii) Prudential Assurance Company Limited acting by its investment manager M&G Investment Management Limited ("M&G"), for a combined investment of £40 million through an issuance of ordinary shares. The capital raised will continue to drive the momentum of the Company and offers further significant validation of the platform. We are very excited to continue advancing the company and further developing and expanding our synthetic DNA offerings. We are very pleased to welcome Elevage Medical Technologies and M&G plc to our shareholder register. #thefutureissynthetic #4basebio Patient Square Capital Read the full press release here - https://lnkd.in/exhrPteZ
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Attending the 18th Liposome Research Days this week? Make sure to visit our posters to delve into our transformative advancements in non-viral gene delivery. Looking forward to insightful discussions! See our poster schedule below 🧬 #LRD #LNP #Nanoparticles
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Catch us at the 18th Liposome Research Days (LRD) 2024 conference, titled "Delivering Innovation and Driving Applications." The conference will be held today from June 26 to 29, 2024, at the Technology and Innovation Centre (TIC), University of Strathclyde in Glasgow. Meet with Emily Young, Formulation Lead Scientist and Hassan Idris, Scientist who will be there to connect and present their posters on transformative advancements in non-viral gene delivery. More poster info to follow 🧬 Dr Emily young will also be presenting a talk titled “Hermes™ Lipopolyplex Nanoparticles for Linear hpDNA™ Delivery” on the 28th June at 9:40am. Make sure not to miss it! #Nanoparticles #LNP #LRD
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We are back again this year at The European mRNA Conference 2024 in Frankfurt, 26-27th June! Catch us at booth #7 where team members Elisa Cuevas, Head of NPD and Zoe Whiffen, Head of MSAT will be there to share insights into 4basebio’s innovative technology and how it is paving the way for next-generation mRNA therapeutics and vaccines. During the conference Dr Elisa Cuevas will be delivering a talk titled ‘Novel Synthetic DNA and Delivery Modalities for mRNA Therapies and Vaccines’ where she will be speaking on: 🧬 Limitations of conventional linearised plasmid as an IVT template 🧬 opDNA™ as a synthetic DNA template enhancing IVT processes without the need of enzymatic linearisation 🧬 The efficiency of opDNA™ with respect to mRNA yields and effective gene expression 🧬 Hermes™ nanoparticles for improved stability in nanoparticle-based delivery The talk will be at 5pm on the 26th June– make sure not to miss it! #mRNAvaccines #SyntheticDNA #mRNAtherapeutics Pharma Events by IQ Hub
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We are live at British Society for Gene and Cell Therapy (BSGCT)! Great to see team members Zoe Whiffen, Deborah Entiriwaa and Vanina Hangu representing 4basebio and showcasing our work. Make sure to stop by! #BSGCT24 #SyntheticDNA #Geneediting #Cellandgenetherapy