Renato Brito Baleeiro, Ph.D

Renato Brito Baleeiro, Ph.D

London, England, United Kingdom
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About

I am a biomedical scientist with a solid background in Immuno-oncology and 15+ years of…

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Experience

  • VacV Biotherapeutics Graphic

    VacV Biotherapeutics

    London, England, United Kingdom

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    London, England, United Kingdom

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    Berlin, Germany

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    Berlin

Education

  • Humboldt-Universität zu Berlin Graphic

    Humboldt-Universität zu Berlin

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    Published scientific articles in:
    - Journal of Investigative Dermatology
    - PLoS One
    - ACS Chemical Biology
    - Future Medicinal Chemistry

    Presented scientific works at:
    - 11th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology, 26-30 September 2010, Lugano, Switzerland;

    - 12th International Workshop on Langerhans Cells, 3-6 November 2011, Innsbruck, Austria.

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    Activities and Societies: Trainee teacher in immunology for the course of pharmacy and biochemistry.

    Published scientific articles in:
    - Cancer Immunology and Immunotherapy
    - Molecular Immunology
    - Brain, Behavior and Immunity

    Presented scientific works at:
    - XXXI Meeting of the Brazilian Society for Immunology (Signaling in the Immune System). Búzios, RJ, Brazil, 2006;

    - 13th International Congress of Immunology, Rio de Janeiro, RJ, Brasil, 2007.

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    - Trainee in serology and immunodiagnostic assays at the Centre for Zoonoses Control in São Paulo, Brazil.

Publications

Patents

  • ANTIGEN-LOADED CHITOSAN NANOPARTICLES FOR IMMUNOTHERAPY

    Issued EU WO/2015/185180

    The present invention is directed to nanoparticles comprising chitosan and an antigen, whereby the chitosan has a degree of deacetylation of about 90% and a molecular weight from 5 kDa to 80 kDa, to microparticles containing such nanoparticles as well as to a process for preparation of such particles. The particles are usable for vaccination.

    See patent

Projects

  • Adoptive T-cell therapy for pancreatic cancer targeting KRAS mutations

    - Present

  • Oncolytic virotherapy for breast and pancreatic tumors

    - Present

  • Personalized neo-antigen-based vaccines for triple-negative breast cancer and pancreatic cancer

    - Present

  • Leishmania vaccines

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    Development of prophylactic and therapeutic vaccines for induction of T-cellular immune responses against leishmaniasis including antigen selection and optimisation, vaccine design and vaccine delivery.

  • Platform for efficient epithelial transport and pharmaceutical application through novel particulate delivery system

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  • Mechanisms of antigen cross-presentation by human dendritic cells

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  • Development of topical needle-free vaccination platforms

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  • Dendritic cell-tumor cell hybrid vaccination for metastatic cancer

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  • Functional modulation of dendritic cells and their precursors in the tumor microenvironment

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Honors & Awards

  • Nanomedicine Award 2015 - Best Early clinical stage project

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    The Nanomedicine Award aims to reward projects that have developed innovative solutions based on nanomedicine that can ultimately change the way diseases are treated or diagnosed and that could provide new tools for physicians and large benefits to patients. Open to companies, academic and private researchers from European and non-European countries, the Nanomedicine Award aims to honor the best international nanomedicine innovations.

  • The Young Scientist Award

    12th International Workshop on Langerhans Cells - Innsbruck, Austria

  • Scholarship from the German Academic Exchange Service (DAAD) to conduct the Ph.D studies in Germany

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Languages

  • Portuguese

    Native or bilingual proficiency

  • English

    Native or bilingual proficiency

  • German

    Limited working proficiency

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