Renato Brito Baleeiro, Ph.D
London, England, United Kingdom
4K followers
500+ connections
About
I am a biomedical scientist with a solid background in Immuno-oncology and 15+ years of…
Articles by Renato
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Innovative Cancer Therapies: The Promise of Targeting CD47 in Immunotherapy
Innovative Cancer Therapies: The Promise of Targeting CD47 in Immunotherapy
By Renato Brito Baleeiro, Ph.D
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Beyond CAR T-cells: The emergence of CAR NK in Cancer Immunotherapy
Beyond CAR T-cells: The emergence of CAR NK in Cancer Immunotherapy
By Renato Brito Baleeiro, Ph.D
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Overcoming Resistance to anti-PD1 Treatment in Cancer Immunotherapy
Overcoming Resistance to anti-PD1 Treatment in Cancer Immunotherapy
By Renato Brito Baleeiro, Ph.D
Contributions
Activity
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Adenovirus Vaccine Targeting Kinases Shows Strong Antitumour Immunity in Solid Tumour Models Researchers developed adenovirus (Ad) vaccines…
Adenovirus Vaccine Targeting Kinases Shows Strong Antitumour Immunity in Solid Tumour Models Researchers developed adenovirus (Ad) vaccines…
Shared by Renato Brito Baleeiro, Ph.D
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Don't let the noise distract you. This industry is doing some incredible work. The future is bright! What would you name the other…
Don't let the noise distract you. This industry is doing some incredible work. The future is bright! What would you name the other…
Liked by Renato Brito Baleeiro, Ph.D
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Será o fim do Óxido nitroso / Protóxido de Azoto no ambiente hospitalar!!! O Hospital das Clínicas da Faculdade de Medicina de Botucatu (HCFMB) e o…
Será o fim do Óxido nitroso / Protóxido de Azoto no ambiente hospitalar!!! O Hospital das Clínicas da Faculdade de Medicina de Botucatu (HCFMB) e o…
Liked by Renato Brito Baleeiro, Ph.D
Experience
Education
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Humboldt-Universität zu Berlin
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Published scientific articles in:
- Journal of Investigative Dermatology
- PLoS One
- ACS Chemical Biology
- Future Medicinal Chemistry
Presented scientific works at:
- 11th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology, 26-30 September 2010, Lugano, Switzerland;
- 12th International Workshop on Langerhans Cells, 3-6 November 2011, Innsbruck, Austria. -
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Activities and Societies: Trainee teacher in immunology for the course of pharmacy and biochemistry.
Published scientific articles in:
- Cancer Immunology and Immunotherapy
- Molecular Immunology
- Brain, Behavior and Immunity
Presented scientific works at:
- XXXI Meeting of the Brazilian Society for Immunology (Signaling in the Immune System). Búzios, RJ, Brazil, 2006;
- 13th International Congress of Immunology, Rio de Janeiro, RJ, Brasil, 2007. -
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- Trainee in serology and immunodiagnostic assays at the Centre for Zoonoses Control in São Paulo, Brazil.
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Publications
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Personalized neoantigen viro-immunotherapy platform for triple-negative breast cancer
Journal for ImmunoTherapy of Cancer
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Immune checkpoint inhibitors in cancer therapy
The Journal of Biomedical Research
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Combining R-DOTAP and a particulate antigen delivery platform to trigger dendritic cell activation: Formulation development and in-vitro interaction studies
International Journal of Pharmaceutics
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Nanoparticle-Based Mucosal Vaccines Targeting Tumor-Associated Antigens to Human Dendritic Cells
Journal of Nanomedical Nanotechnology
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Combinatorial chemistry by ant colony optimization
Future Medicinal Chemistry
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Exhaustive proteome mining for functional MHC-I ligands
ACS Chemical Biology
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Topical vaccination with functionalized particles targeting dendritic cells
Journal of Investigative Dermatology
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Cohabitation with a B16F10 melanoma-bearer cage mate influences behavior and dendritic cell phenotype in mice
Brain, Behavior, and Immunity
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High frequency of immature dendritic cells and altered in situ production of interleukin-4 and tumor necrosis factor-alpha in lung cancer
Cancer Immunology and Immunotherapy
Patents
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ANTIGEN-LOADED CHITOSAN NANOPARTICLES FOR IMMUNOTHERAPY
Issued EU WO/2015/185180
The present invention is directed to nanoparticles comprising chitosan and an antigen, whereby the chitosan has a degree of deacetylation of about 90% and a molecular weight from 5 kDa to 80 kDa, to microparticles containing such nanoparticles as well as to a process for preparation of such particles. The particles are usable for vaccination.
Projects
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Adoptive T-cell therapy for pancreatic cancer targeting KRAS mutations
- Present
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Oncolytic virotherapy for breast and pancreatic tumors
- Present
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Personalized neo-antigen-based vaccines for triple-negative breast cancer and pancreatic cancer
- Present
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Leishmania vaccines
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Development of prophylactic and therapeutic vaccines for induction of T-cellular immune responses against leishmaniasis including antigen selection and optimisation, vaccine design and vaccine delivery.
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Platform for efficient epithelial transport and pharmaceutical application through novel particulate delivery system
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Mechanisms of antigen cross-presentation by human dendritic cells
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Development of topical needle-free vaccination platforms
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Dendritic cell-tumor cell hybrid vaccination for metastatic cancer
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Functional modulation of dendritic cells and their precursors in the tumor microenvironment
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Honors & Awards
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Nanomedicine Award 2015 - Best Early clinical stage project
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The Nanomedicine Award aims to reward projects that have developed innovative solutions based on nanomedicine that can ultimately change the way diseases are treated or diagnosed and that could provide new tools for physicians and large benefits to patients. Open to companies, academic and private researchers from European and non-European countries, the Nanomedicine Award aims to honor the best international nanomedicine innovations.
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The Young Scientist Award
12th International Workshop on Langerhans Cells - Innsbruck, Austria
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Scholarship from the German Academic Exchange Service (DAAD) to conduct the Ph.D studies in Germany
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Languages
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Portuguese
Native or bilingual proficiency
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English
Native or bilingual proficiency
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German
Limited working proficiency
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Join now to viewMore activity by Renato
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Oncolytic vaccinia virus selectively targets and depletes tumour-infiltrating regulatory and exhausted T cells. Oncolytic vaccinia virus (VV) can…
Oncolytic vaccinia virus selectively targets and depletes tumour-infiltrating regulatory and exhausted T cells. Oncolytic vaccinia virus (VV) can…
Shared by Renato Brito Baleeiro, Ph.D
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CD74 Targeting on Macrophages Enhances Response to Neoadjuvant Chemotherapy and PD-1 Blockade in Cervical Cancer This study explored the effects of…
CD74 Targeting on Macrophages Enhances Response to Neoadjuvant Chemotherapy and PD-1 Blockade in Cervical Cancer This study explored the effects of…
Shared by Renato Brito Baleeiro, Ph.D
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