About
As a seasoned biostatistician with extensive experience in statistical methodology, data…
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That show is an insult for all the athletes taking part in the games. The creator group of this nonsense practically ruined the Olympic spirit that…
That show is an insult for all the athletes taking part in the games. The creator group of this nonsense practically ruined the Olympic spirit that…
Liked by Vasilis Nikolaou, PhD
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Amazing day at #DSFMayday yesterday. Really good to make a lot of new connections, see a few old ones and learn a lot from industry leaders. A few…
Amazing day at #DSFMayday yesterday. Really good to make a lot of new connections, see a few old ones and learn a lot from industry leaders. A few…
Liked by Vasilis Nikolaou, PhD
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Honored to be part of this great paper! Exciting news! The latest data sheds light on the role of immune cell regulation in the progression of CH to…
Honored to be part of this great paper! Exciting news! The latest data sheds light on the role of immune cell regulation in the progression of CH to…
Liked by Vasilis Nikolaou, PhD
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Variable risk of atopic disease due to indoor fungal exposure in NHANES 2005-2006
Clinical and Experimental Allergy
Exposure to damp indoor environments is associated with increased risk of eczema, allergy and asthma. The role of dampness-related exposures and risk of allergic diseases are yet to be fully explored in a US population.
We assess whether exposure to fungi, house dust mites and endotoxin increase the risk of eczema, allergy and asthma in children and adults participating in NHANES 2005-2006.
A total of 8,412 participants (2,849 were children aged between 6 and 17 years) were…Exposure to damp indoor environments is associated with increased risk of eczema, allergy and asthma. The role of dampness-related exposures and risk of allergic diseases are yet to be fully explored in a US population.
We assess whether exposure to fungi, house dust mites and endotoxin increase the risk of eczema, allergy and asthma in children and adults participating in NHANES 2005-2006.
A total of 8,412 participants (2,849 were children aged between 6 and 17 years) were recruited in the 2005-2006 survey. We used multiple logistic regression to investigate whether mildew/musty odour, and increased concentrations of Alternaria alternata allergen, Aspergillus fumigatus antigens, house dust mite and endotoxin antigens increase risk of eczema, allergy and asthma. We stratified models by total IgE <170 and ≥170 KU/L to assess allergic and non-allergic asthma outcomes. Exposure to multiple biological agents and risk of reporting eczema, allergy and asthma was also investigated.
Reporting of a mildew/musty odour was associated with increased risk of childhood asthma (OR 1.60; 95% CI 1.17-2.19), and adult eczema, allergy and asthma (OR 1.92; 95% CI 1.39-2.63, OR 1.59 95% CI 1.26-2.02 and OR 1.61 95% CI 1.00-2.57, respectively). Risk of asthma was associated with total IgE ≥170 KU/L in children (OR 1.81; 95% CI 1.01-3.25) and total IgE <170 KU/L in adults (OR 1.91; 95% CI 1.07-3.42). Children and adults exposed to more than eight biological agents present in the home were at reduced risk of eczema (OR 0.17; 95% CI 0.04-0.77) and asthma (OR 0.49; 95% CI 0.25-0.97), respectively.Other authorsSee publication -
Higher energy efficient homes are associated with increased risk of doctor diagnosed asthma in a UK subpopulation
Environ Int.
The United Kingdom (UK) has one of the highest prevalence of asthma in the world, which represents a significant economic and societal burden. Reduced ventilation resulting from increased energy efficiency measures acts as a modifier for mould contamination and risk of allergic diseases. To our knowledge no previous study has combined detailed asset management property and health data together to assess the impact of household energy efficiency (using the UK Government's Standard Assessment…
The United Kingdom (UK) has one of the highest prevalence of asthma in the world, which represents a significant economic and societal burden. Reduced ventilation resulting from increased energy efficiency measures acts as a modifier for mould contamination and risk of allergic diseases. To our knowledge no previous study has combined detailed asset management property and health data together to assess the impact of household energy efficiency (using the UK Government's Standard Assessment Procedure) on asthma outcomes in an adult population residing in social housing.
RESULTS:
Eighteen percent of our target social housing population were recruited into our study. Adults had a mean age of 59 (SD±17.3) years and there was a higher percentage of female (59%) and single occupancy (58%) respondents. Housing demographic characteristics were representative of the target homes. A unit increase in household Standard Assessment Procedure (SAP) rating was associated with a 2% increased risk of current asthma, with the greatest risk in homes with SAP >71. We assessed exposure to mould and found that the presence of a mouldy/musty odour was associated with a two-fold increased risk of asthma (OR 2.2 95%; CI 1.3-3.8). A unit increase in SAP led to a 4-5% reduction in the risk of visible mould growth and a mouldy/musty odour.
CONCLUSION:
Energy efficiency may increase the risk of current adult asthma in a population residing in social housing. This association was not significantly modified by the presence of visible mould growth, although further research is needed to investigate the interaction between other demographic and housing characteristic risk factors, especially the impact of fuel poverty on indoor exposures and health outcomes.Other authorsSee publication
More activity by Vasilis
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We developed an eXplainable AI (XAI) framework: SAGE. It guides the creation of operational XAI solutions by focusing on context for user-centric…
We developed an eXplainable AI (XAI) framework: SAGE. It guides the creation of operational XAI solutions by focusing on context for user-centric…
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Yet another innovative piece of research! #biomarkers #cardiovasculardisease #machinelearning #AI #europeansocieyofmedicine #medicalresearcharchives
Yet another innovative piece of research! #biomarkers #cardiovasculardisease #machinelearning #AI #europeansocieyofmedicine #medicalresearcharchives
Shared by Vasilis Nikolaou, PhD
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Call for papers for the new special issue on AI and precision medicine #ai #precisionmedicine #machinelearning #diagnostics
Call for papers for the new special issue on AI and precision medicine #ai #precisionmedicine #machinelearning #diagnostics
Shared by Vasilis Nikolaou, PhD
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Dear #multiomics friends! 😀 I am very honoured and happy to be invited together my friend Vasilis Nikolaou, PhD as guest Editor in this Special…
Dear #multiomics friends! 😀 I am very honoured and happy to be invited together my friend Vasilis Nikolaou, PhD as guest Editor in this Special…
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If you are curious to know a bit more about my journey in #organizationalneuroscience... (and a big thanks to Sasha Korobov for hosting this podcast!)
If you are curious to know a bit more about my journey in #organizationalneuroscience... (and a big thanks to Sasha Korobov for hosting this podcast!)
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#psiconference2023 - my #psicommunity perspective! One of my favourite things about being a PSI member and volunteer is the community feel! Every…
#psiconference2023 - my #psicommunity perspective! One of my favourite things about being a PSI member and volunteer is the community feel! Every…
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"The University of Surrey is now in the top 50 of the Times Higher Education's Impact Rankings. This also means we rank top 10 out of UK…
"The University of Surrey is now in the top 50 of the Times Higher Education's Impact Rankings. This also means we rank top 10 out of UK…
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Congratulations to University of Exeter's Dr Sarah Bailey, who has won the Outstanding Early Career Researcher Award 2023 for her work in detecting…
Congratulations to University of Exeter's Dr Sarah Bailey, who has won the Outstanding Early Career Researcher Award 2023 for her work in detecting…
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We're showing our support this #RareDiseaseDay by amplifying the rare disease community's work and taking part in the campaigns they've…
We're showing our support this #RareDiseaseDay by amplifying the rare disease community's work and taking part in the campaigns they've…
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Call for papers for Life MDPI special issue: https://lnkd.in/ewRU3kEC #machinelearning #artficialintelligence #mdpi #respiratorydiseases…
Call for papers for Life MDPI special issue: https://lnkd.in/ewRU3kEC #machinelearning #artficialintelligence #mdpi #respiratorydiseases…
Shared by Vasilis Nikolaou, PhD
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Leading by example with strength and determination though a major crisis of an unprecedented global scale. Thank you for having set a benchmark of…
Leading by example with strength and determination though a major crisis of an unprecedented global scale. Thank you for having set a benchmark of…
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