epistasis (n.)

before vowels reduced to ep-, before aspirated vowels eph-, word-forming element meaning "on, upon, above," also "in addition to; toward, among," from Greek epi "upon, at, close upon (in space or time), on the occasion of, in addition," also "after," from PIE *epi, *opi "near, at, against" (source also of Sanskrit api "also, besides;" Avestan aipi "also, to, toward;" Armenian ev "also, and;" Latin ob "toward, against, in the way of;" Oscan op, Greek opi- "behind;" Hittite appizzis "younger;" Lithuanian ap- "about, near;" Old Church Slavonic ob "on"). A productive prefix in Greek; also used in modern scientific compounds (such as epicenter).

*stā-, Proto-Indo-European root meaning "to stand, set down, make or be firm," with derivatives meaning "place or thing that is standing."

It forms all or part of: Afghanistan; Anastasia; apostasy; apostate; armistice; arrest; assist; astatic; astatine; Baluchistan; bedstead; circumstance; consist; constable; constant; constitute; contrast; cost; desist; destination; destine; destitute; diastase; distance; distant; ecstasy; epistasis; epistemology; establish; estaminet; estate; etagere; existence; extant; Hindustan; histidine; histo-; histogram; histology; histone; hypostasis; insist; instant; instauration; institute; interstice; isostasy; isostatic; Kazakhstan; metastasis; obstacle; obstetric; obstinate; oust; Pakistan; peristyle; persist; post (n.1) "timber set upright;" press (v.2) "force into service;" presto; prostate; prostitute; resist; rest (v.2) "to be left, remain;" restitution; restive; restore; shtetl; solstice; stable (adj.) "secure against falling;" stable (n.) "building for domestic animals;" stage; stalag; stalwart; stamen; -stan; stance; stanchion; stand; standard; stanza; stapes; starboard; stare decisis; stasis; -stat; stat; state (n.1) "circumstances, conditions;" stater; static; station; statistics; stator; statue; stature; status; statute; staunch; (adj.) "strong, substantial;" stay (v.1) "come to a halt, remain in place;" stay (n.2) "strong rope which supports a ship's mast;" stead; steed; steer (n.) "male beef cattle;" steer (v.) "guide the course of a vehicle;" stem (n.) "trunk of a plant;" stern (n.) "hind part of a ship;" stet; stoa; stoic; stool; store; stound; stow; stud (n.1) "nailhead, knob;" stud (n.2) "horse kept for breeding;" stylite; subsist; substance; substitute; substitution; superstition; system; Taurus; understand.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit tisthati "stands;" Avestan histaiti "to stand;" Persian -stan "country," literally "where one stands;" Greek histēmi "put, place, cause to stand; weigh," stasis "a standing still," statos "placed," stylos "pillar;" Latin sistere "stand still, stop, make stand, place, produce in court," status "manner, position, condition, attitude," stare "to stand," statio "station, post;" Lithuanian stojuos "I place myself," statau "I place;" Old Church Slavonic staja "place myself," stanu "position;" Gothic standan, Old English standan "to stand," stede "place;" Old Norse steði "anvil;" Old Irish sessam "the act of standing."