The Unofficial Guide to Medical Research, Audit and Teaching
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The Unofficial Guide to Medical Research, Audit and Teaching - Unofficial Guide to Medicine
The Unofficial Guide to Medical Research, Audit, and Teaching
FIRST EDITION
CEEN-MING TANG BA (Hons) MedSci
Final Year Medical Student, University of Oxford, UK
ZESHAN QURESHI BM MSc BSc (Hons)
Academic Clinical Fellow, Great Ormond Street,
UK and Institute of Global Health, UCL, UK
COLIN FISCHBACHER MBChB FFPH FRCP(Ed)
Clinical Director for Information, NHS National Services Scotland,
Honorary Senior Lecturer, University of Edinburgh, UK
ISBN 978-0957149984
eISBN 978-1-910399-08-8
Text, design and illustration © Zeshan Qureshi 2015
Edited by Ceen-Ming Tang, Zeshan Qureshi and Colin Fischbacher
Published by Zeshan Qureshi. First published 2015
All rights reserved; no part of this publication may be reproduced, stored in a retrieval system, transmitted in any form, or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publishers.
Original design by Zeshan Qureshi. Page layout by SWATT Design Ltd
Illustrated by SWATT Design Ltd
A catalogue record for this book is available from the British Library.
Ceen-Ming Tang’s Acknowledgements:
I would like to thank my colleagues, mentors, friends, and, most of all, my parents for their unwavering support through the years, without which none of this would have been possible.
Although we have tried to trace and contact copyright holders before publication, in some cases this may not have been possible. If contacted, we will be pleased to rectify any errors or omissions at the earliest opportunity. Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary. Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods, they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility. With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the publisher nor the authors, contributors, or editors assume any liability for any injury and/or damage to persons or property that may occur as a result of any person acting or not acting based on information contained in this book
Printed and bound by Cambrian Printers in UK
INTRODUCTION
Junior doctors spend years of training developing the clinical acumen required to fulfil their day-to-day role, acquiring the ability to recognise and manage both acute and chronic medical conditions. However, the role of the doctor extends beyond this, and many medical students feel unprepared for their inevitable roles as teachers, researchers, and managers. With this in mind, this book explores these roles in more detail.
Research affects all doctors’ practice, from a primary care physician in a rural practice to a professor in a large teaching hospital. Knowing how a clinical problem is translated into a research question is a challenge that both clinicians and researchers need to be involved in. Imagine that you are the respiratory physician running a clinic for idiopathic pulmonary fibrosis. In being able to see the limitations of everyday practice, you as the clinician can identify the problems which need addressing. For example, this may be ineffective drugs, inaccurate monitoring of disease progression, or poor subtyping of the disease, all of which ultimately compromise management. The researcher can then help address these problems by identifying the specific question that needs to be answered. For example, this may require a basic science
approach such as revisiting the pathogenesis of lung fibrosis to identify new drug targets, or searching for new drugs at known targets. It may require a more clinical approach, such as finding ways to improve compliance with current therapy, monitoring of disease progression, or attendance at outpatient follow-up. This entire process hinges on understanding what is known about the subject, and what still needs to be learned.
It is crucial that clinicians are able to interpret research findings and understand the implications for their practice. Is this statistically significant result also clinically important for my patients? Was this particular research done on patients comparable to the one that I am treating? Clinicians must also be aware of the clinical exceptions when interpreting guidelines. Hence, a firm grasp of evidence-based medicine is beneficial, even for clinicians who are not actively carrying out research.
Other benefits that come from doing research include the development of teamwork and leadership skills. You learn not only to work within a team, but to work towards deadlines, deliver presentations, and write scientifically. You also have the opportunity to think critically, and find answers for yourself. The answer because that’s what it says in the textbook
or that’s how things are done
simply isn’t good enough. If the answer to your question is unsatisfactory, as it is for many areas of medicine, you can learn to think critically and at least try to answer the question empirically for yourself.
Clinicians today are also actively involved in clinical governance and teaching. Participating in clinical governance may allow you to improve the quality of patient care more rapidly than through a research route. For example, audits are necessary to see whether new guidelines, created as a result of new research, have been implemented successfully. As a doctor, you should also teach and oversee the work of your less-experienced colleagues. This is not only an obligation, but you can also learn the subject in more detail by teaching it.
The practical benefits of doing research, participating in clinical governance, and teaching are quite clear. Beyond the core skills acquired through such activities, participation in audits and/or quality improvement projects are also a requirement for almost all trainees. Evidence of teaching is also a key component of your portfolio. Recruitment panels recognise the importance of the skills acquired through these processes, and presentations, publications, and teaching are rewarded with points during job applications. Differentiating yourself from other medics or surgeons is hard! Involvement in research, especially of a quality which has resulted in presentation or publication, demonstrates a keen interest in the field and will allow you to stand out more than you would have otherwise. All of this is crucial in a competitive job market. In short, aiming for publications and participating in research, audits, and teaching is beneficial for everyone.
This book does not aim to make you an expert in research. Our first and foremost goal is to encourage you to think critically. To that end, we include simple introductory guides to different aspects of research and convenient checklists to help you appraise the literature. We also want to make clinical governance and teaching a less daunting prospect. In that respect, we provide a handy step-by-step guide for designing audits, and introduce other aspects of clinical governance such as service evaluation and quality improvement projects. For the new teacher, we pass down our tips for teaching and guide you through organising a teaching programme. Ultimately, we want to help you to find the right project to help you meet your personal career objectives, whether this be as a clinician, researcher, manager, or educator.
Additionally, we want you to get involved. This textbook has been written mainly by junior doctors and students just like you because we believe:
...that fresh graduates have a unique perspective on what works for students. We have tried to capture the insight of students and recent graduates to make the language we use to discuss this complex material more digestible for students.
...that texts are in constant need of being updated. Every student has the potential to contribute to the education of others by innovative ways of thinking and learning. This book is an open collaboration with you.
You have the power to contribute something valuable to medicine; we welcome your suggestions and would love for you to get in touch.
Please get in touch and be part of the medical education project.
Facebook:
www.facebook.com/TheUnofficialGuideToMedicine
Email:
FOREWORD
The Unofficial Guide to Medical Research, Audit and Teaching is a fantastic book for medical students and doctors. It stands out from all the other books because it is so tremendously practical. It is clear that it is based upon the years of experience of successful academic doctors who have published extensively as students and now as doctors, and it shares the best ways to achieve success.
Whilst students are often in want of a mentor, the basics of how to approach research opportunities and how to use them are often unclear. This book sets forth to answer the key questions those starting on an academic path may have, and is written in an easy-to-follow, accurate, and thorough way from start to end. It is, most of all, tremendously practical and useful, for example giving excellent tips and examples of how to approach supervisors, what to discuss in the initial meeting, and ways to find funding options.
This book is very highly recommended to all medical students and doctors whether they are doing or supervising teaching, audits, or clinical research.
– John J Park
Editor-in-Chief, Res Medica,
Journal of the Royal Society of Medicine
When I first started as a lecturer, a colleague advised me to think of a clinical academic career as a stool with three legs, namely: clinical practice (including management, audit, clinical governance and economics), teaching (including different approaches to teaching and assessment, and the management of courses or attachments), and research (including defining appropriate research questions, applying for funding, collecting and analysing data, and diseminating the findings through publication). Building expertise in each of these three areas of activity is essential for the aspiring clinical academic, for the medical profession as a whole, and for ongoing improvements in patient care and population health. During medical school and the early years of postgraduate training, the emphasis is necessarily on the first of these - preparing new doctors to undertake clinical practice safely and effectively. This book is unique in seeking to introduce the other important aspects of a clinical academic career which are not typically covered. This is no easy task, as each is complex and diverse, with extensive literature, different ways of thinking, and new terminology, skills and techniques. For example, many different types of qualitative research have been described which cannot easily be summarised as a single approach. The authors have had to be selective and brief, but have successfully managed to synthesise this literature into a single coherent and very accessible textbook.
This will be a great introductory text for those who want to pursue a clinical academic career, and for everyone else will provide a range of concepts, tools and approaches which will be useful in any medical speciality.
– Michael Ross
BSc MBChB MRCGP EdD
Co-Editor-in-Chief, The Clinical Teacher.
Senior Clinical Lecturer, Centre for Medical Education, The University of Edinburgh
CONTRIBUTORS
EDITORS
AUTHORS
REVIEWERS
TABLE OF CONTENTS
1. GETTING INVOLVED IN RESEARCH
(Ceen-Ming Tang, Heather Chester, Tung On Yau, Sze Kan Cecilia Cheuk, Zeshan Qureshi)
Opportunities To Do Research
Finding The Right Project
Finding The Right Mentor
Defining A Research Question
Designing Your Research Study
2. LITERATURE SEARCHING
(Ceen-Ming Tang, Zeshan Qureshi, Heather Chester)
Introduction To Literature Searching
Designing A Search Strategy
Identifying Relevant Scientific Papers From Your Search Results
User Guides To Individual Literature Search Databases
3. STATISTICS AND KEY EPIDEMIOLOGICAL CONCEPTS
(Colin Fischbacher, Zeshan Qureshi)
Developing An Analysis Plan
Statistical Analysis
Describing Variables
Precision
Size Difference Between Two Groups
Associations Between Continuous Variables
Other Approaches To Examining Associations Between Variables
Important Epidemiological Concepts
4. BASIC SCIENCE RESEARCH STUDIES
(Tung On Yau, Ceen-Ming Tang, Sze Kan Cecilia Cheuk)
Lab Notebooks
Laboratory Equipment
Commonly Used Calculations
Techniques In Molecular Biology
Techniques In Drug Discovery
Techniques In Cell Culture And Animal Studies
5. QUALITATIVE RESEARCH
(Colin Fischbacher, Zeshan Qureshi)
How Is It Different From Quantitative Research?
Key Characteristics Of Qualitative Research
Data Collection Methods In Qualitative Research
Data Analysis And Reporting
6. ECONOMIC EVALUATION
(Tim Colbourn)
Types Of Economic Evaluation
How To Conduct An Economic Evaluation
How To Assess An Economic Evaluation
7. COMMUNICATING AND PUBLISHING RESEARCH
(Ceen-Ming Tang, Zeshan Qureshi)
The Structure Of A Scientific Paper
Submission To Medical Journals
Opinion Pieces And New Forms Of Communication
Conferences And Research Presentations
8. CRITICAL APPRAISAL
(Ceen-Ming Tang, Colin Fischbacher, Zeshan Qureshi, James Brooks, Sze Kan Cecilia Cheuk)
A Step-By-Step Guide To Critical Appraisal
A Worked Example Using A Published Manuscript
Checklists For Critical Appraisals By Study Type
9. CLINICAL GOVERNANCE
(Ceen-Ming Tang, Rayna Patel)
An Introduction To Clinical Governance
Clinical Audit
Service Evaluation And Patient Questionnaires
Quality Improvement Projects
Leadership And Management
10. TEACHING
(Ceen-Ming Tang, Debbie Aitken, Janet Skinner)
Teaching Opportunities
Teaching Formats
How To Set Up A Teaching Programme
How To Plan A Lesson
Teaching Skills
Medical Education Research
Keeping A Teaching Portfolio
11. HEALTHCARE INNOVATION AND ENTREPRENEURSHIP
(Ceen-Ming Tang)
Identifying And Prioritising Needs
Market Analysis
Designing An Innovation
INDEX
Chapter 1:
Getting Involved in Research
Opportunities To Do Research
Finding The Right Project
Finding The Right Mentor
Defining A Research Question
Designing Your Research Study
This chapter will introduce you to research. It will give you an idea as to what opportunities are available to develop as a researcher, and how to take advantage of such opportunities when they arise.
OPPORTUNITIES TO DO RESEARCH
Academic medicine is a broad term for a variety of career paths with differing degrees of clinical and research involvement. Opportunities are wide-ranging, from writing a case report to obtaining an academic medical post or completing a PhD. Broadly speaking, those who want only occasional or relatively short-term involvement in research should focus on finding an appropriate small project and mentor. Many people will just approach a mentor and work on a small research project in their spare time. For those with an ongoing interest in academic medicine, finding a way to obtain allocated time to engage in longer-term research may be best. This chapter considers the more formal opportunities to engage with research.
There are many different opportunities to do research at various points throughout your career, and many questions are asked about the ideal
time to do research. Unfortunately, there is no simple answer to this question. The answer varies considerably between countries, and it also depends on taking advantage of opportunities as they arise.
COURSES AND RESEARCH DEGREES
Table 1 below summarises different options for formal research qualifications. It is important to explore and consider these carefully as they are a significant commitment and will slow your progression through clinical training. Nonetheless, they are valuable opportunities that may allow you to gain skills and experience throughout your career.