Circulation Reports
Online ISSN : 2434-0790
Advance online publication
Displaying 1-4 of 4 articles from this issue
  • Takeshi Shimizu, Yuya Sakuma, Yuuki Muto, Fumiya Anzai, Yusuke Kimishi ...
    Article type: ORIGINAL ARTICLE
    Subject Area: Ischemic Heart Disease
    Article ID: CR-24-0070
    Published: August 07, 2024
    Advance online publication: August 07, 2024
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    Supplementary material

    Background: Cardiovascular risk factors are associated with increased risk of future cancer. However, the relationship between quantitative parameters of atherosclerosis and future cancer risk is unclear.

    Methods and Results: A total of 1,057 consecutive patients with coronary artery disease was divided into 2 groups according to the cutoff value of the cardio-ankle vascular index (CAVI) derived by receiver operating characteristic curve analysis: low CAVI group (CAVI <8.82; n=487), and high CAVI group (CAVI ≥8.82; n=570). Patients in the high CAVI group were older and had a higher prevalence of diabetes, chronic kidney disease, anemia and history of stroke compared with patients in the low CAVI group. There were 141 new cancers during the follow-up period. The cumulative incidence of new cancer was significantly higher in the high CAVI group than in the low CAVI group (P=0.001). In a multivariate Cox proportional hazard analysis, high CAVI was found to be an independent predictor of new cancer diagnosis (hazard ratio 1.62; 95% confidence interval 1.11–2.36; P=0.012). In the analysis of individual cancer types, high CAVI was associated with lung cancer (hazard ratio 2.85; 95% confidence interval 1.01–8.07; P=0.049).

    Conclusions: High CAVI was associated with the risk of future cancer in patients with coronary artery disease.

  • Norihisa Miyawaki, Kenichi Ishizu, Shinichi Shirai, Katsunori Miyahara ...
    Article type: ORIGINAL ARTICLE
    Subject Area: Cardiovascular Intervention
    Article ID: CR-24-0078
    Published: August 06, 2024
    Advance online publication: August 06, 2024
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    Supplementary material

    Background: Cognitive impairment assessed using the Mini-Mental Status Examination (MMSE) is associated with short-term mortality after transcatheter aortic valve implantation (TAVI). We assessed the long-term prognostic impact of cognitive impairment in patients with severe aortic stenosis post-TAVI.

    Methods and Results: We enrolled 1,057 consecutive patients who underwent TAVI at the Kokura Memorial Hospital and prospectively assessed them using the MMSE. Results showed that 319 (30%) patients had cognitive impairment. Compared with normal cognition, cognitive impairment was associated with an increased risk for 5-year all-cause mortality (55% vs. 39%; P<0.001), cardiovascular mortality (23% vs. 14%; P=0.007), and non-cardiovascular mortality (42% vs. 29%; P<0.001). Multivariable analysis showed that cognitive impairment was independently associated with all-cause mortality (adjusted hazard ratio [aHR] 1.37; 95% confidence interval [CI] 1.10–1.70; P=0.005), and this result was consistent regardless of stratification based on age, sex, body mass index, left ventricular ejection fraction and clinical frailty scale without significant interaction. Patients with MMSE scores <16 had a significantly higher mortality rate compared with patients with MMSE scores >25, 21–25, and 16–20, respectively.

    Conclusions: Cognitive impairment assessed using MMSE scores is independently associated with an increased risk for 5-year all-cause mortality in patients undergoing TAVI.

  • Ryuki Chatani, Kota Morikawa, Mitsuru Yoshino, Hiroshi Tasaka, Kazushi ...
    Article type: RAPID COMMUNICATION
    Article ID: CR-24-0045
    Published: August 01, 2024
    Advance online publication: August 01, 2024
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    Background: The introduction of the Perclose vascular closure device (VCD) for atrial fibrillation (AF) ablation procedures in Japan is expected to facilitate early ambulation.

    Methods and Results: The study population comprised 554 patients undergoing AF ablation, of whom 377 successfully underwent Perclose VCD deployment at the end of the procedure. At 4 h after the procedure, 94% (353/377 patients) achieved early hemostasis and 57% (213/377 patients) achieved early ambulation. Notably, 0.5% (2/377 patients) developed acute deep vein thrombosis.

    Conclusions: The Perclose VCD demonstrated promising efficacy in achieving early hemostasis, potentially facilitating early ambulation and discharge in appropriate patients.

  • Atsushi Mizuno, Daisuke Yoneoka, Takuya Kishi, Kenya Kusunose, Chisa M ...
    Article type: RAPID COMMUNICATION
    Article ID: CR-24-0074
    Published: August 01, 2024
    Advance online publication: August 01, 2024
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    Background: The influence of a change to a default X summary posting strategy on article viewership has not been investigated.

    Methods and Results: We conducted a retrospective analysis of X-posting rates and journal viewership data for both the Circulation Journal and Circulation Reports from April 2022 to September 2023. Following protocol modifications in March 2023, there was a notable increase in the X-posting rate from 12.4% to 61.7%, along with an uptick in median access counts to article pages within 30 days, from 175 to 231.5.

    Conclusions: Trend analysis of journal viewership after a default X-posting strategy revealed an increase in viewer access.

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