Cogent Biosciences

Cogent Biosciences

Biotechnology Research

Waltham, Massachusetts 11,003 followers

Precision therapeutics for genetically defined diseases. Real solutions for real challenges.

About us

Cogent Biosciences is a biotechnology company focused on developing novel precision therapies to treat a broad range of patients with unmet medical needs. Cogent’s lead program, bezuclastinib, is designed to selectively and potently inhibit exon 17 mutations found within the KIT receptor tyrosine kinase, including KIT D816V. KIT D816V is responsible for driving a rare and serious condition called Systemic Mastocytosis, and exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling. Bezuclastinib has already exhibited promising early clinical activity and safety in a Phase 1/2 trial in patients with advanced GIST and also has the potential to fill an unmet need for patients living with Systemic Mastocytosis.

Website
http://www.cogentbio.com
Industry
Biotechnology Research
Company size
51-200 employees
Headquarters
Waltham, Massachusetts
Type
Public Company
Founded
2014
Specialties
gastrointestinal stromal tumors (GIST), Oncology, Systemic Mastocytosis, and kinase inhibitors

Locations

  • Primary

    275 Wyman Street

    3rd Floor

    Waltham, Massachusetts 02451, US

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  • 4840 Pearl East Circle

    Suite 100

    Boulder, Colorado 80301, US

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