Conceivable Life Sciences

Every year, tens of thousands of women go through a hormone stimulation cycle to produce as many eggs as possible for the chance to have a baby via IVF. And yet, once the egg retrieval is done, how many patients are aware of what happens to their eggs? 〰Do they know that their eggs are placed in a small petri dish (like the one I am holding) and undergo 100+ manual steps? 〰How often does a doctor take the time to introduce the embryologist in charge of finding the eggs, cleaning the eggs, inseminating them, and converting them into good quality embryos to a patient? 〰 How often are patients ever offered the opportunity to take a look inside an embryology lab, where 90% of the IVF magic happens? Every time I meet an IVF patient, the answer is almost always never. IVF labs today operate behind closed curtains. And when a patient's eggs don't convert into embryos, they just offer another IVF cycle. At Conceivable Life Sciences, we are building technology that will drastically increase the safety of a patient's eggs. Just to name a few ways in which we are prioritizing eggs, Conceivable's technology will make sure that: 🥚 We find 10/10 eggs in a dish (yes, sometimes embryologists are tired and fail to find all of the eggs in a dish) 🥚Denude them gently 🥚And inseminate them without harming the membrane With Conceivable, we are envisioning a future where a patient will not only be invited to come into an embryology lab, but will also be able to track her eggs' journey through an IVF process. No more black boxes or half answers for patients. Excited to join RESOLVE: The National Infertility Association and Gameto in raising awareness about the importance of prioritizing the female patient experience during National Infertility Awareness Week. Please donate here to contribute to the incredible work that Barb Collura and her team do for patients: https://lnkd.in/eHMMDvgk And thank you again Barb Collura for all the work that you do - looking forward to building a future with more transparency for patients, because everyone's #EGGSPERIENCEmatters! #NIAW

In January, our co-founder Alejandro Chavez-Badiola and our Chief Medical Officer Charles Kingsland, MD traveled to Edinburgh, Scotland, to participate in Fertility 24. Take a look at the article to see what Charles had to say!

Today I had the chance to see my first live demo of the Cradle - our fully automated and integrated sperm preparation, egg finding and ICSI robot. César Millán Castillo, our Head of Mechatronics, is doing an incredible job. I cannot emphasize enough how amazing it's been to see him and our team build something that started as a paper napkin sketch, into the gentle, AI-guided robot that it is today. The first two words that came to me when I saw the Cradle in action were: elegance and robustness. Our team has succeeded in combining over 100 steps that happen in an IVF lab today into the Cradle. A robot that will automate intricate procedures that will help enable the miracle of life. Congratulations to our entire Conceivable Life Sciences engineering team (Estefanía Hernández Gerardo Mendizabal Ruiz Victor Rico Alberto Ortiz Barba Victor Medina-Perez José Gregorio Espinoza Figueroa Valentin Zamarripa Gonzalez Carolina López de Anda Mario Reyes ) on such remarkable progress - so proud!

This is a great framing of a combine and conquer approach for aligning our forces and continuing the push for democratization of IVF. Thanks, David Sable!

Despite the CDC's caution against medical tourism, many Americans are opting for affordable IVF care abroad. Dr. Francisco Javier Estrada Garwood, the director of the Dr. Cigüeña clinic in Mexicali, reveals that a staggering 40% of his patients come from the United States. This statistic is eye-opening and underscores the urgent need for accessible fertility care globally—-and nowhere more so than in the U.S. itself. In addition to the high cost of #ivf in America, proximity to care is problematic. Almost 40% of the U.S. population lives more than a one-day's drive from the nearest IVF clinic. Patients should not have to travel vast distances from home to access care. Conceivable’s fully automated IVF lab is not just a technological advancement; it's a geographic and financial solution to the hurdles that individuals grapple with when contemplating IVF. Our mission is to revolutionize fertility care and make IVF treatment affordable to everyone, regardless of where they live. Take a look at the article link in the comments for more info! #invitro #gynecology #womenshealth

NPR astutely captures the stark reality that the IVF journey concludes "either when there’s a baby, the person runs out of money, or they can’t emotionally and physically endure the pain anymore." In light of this, St. Louis Democratic Representative LaDonna Appelbaum's advocacy for legislation mandating comprehensive insurance coverage for infertility diagnosis and treatment, including advanced procedures like IVF, is commendable. We support and applaud Rep. Appelbaum's bold move to enhance insurance coverage for fertility in her state. However, it's crucial to recognize that while such initiatives are steps in the right direction, true global improvement in fertility care necessitates an overhaul of the treatment process itself. And that’s where Conceivable comes in. Make sure to check out the full article - link is in the comments.

As never before, engineers are collaborating with fertility scientists to integrate AI and robotic technologies. We are looking at a future in which the 5 key building blocks of IVF—egg discovery and denuding, sperm selection, ICSI, vitrification and incubation—will all be performed more reliably by precision automated robots, not human beings. Rather than being something that should alarm embryologists, Jacques Cohen, Conceivable’s Chief Science Officer, argues that there has never been a better time to enter the field. #biotechnology #automation #IVF #scienceandtechnology Noor Siddiqui

Workplace silence on matters of infertility leads to feelings of isolation and secrecy while navigating an immensely challenging process, making it all the more difficult. In brief, this is not good for one’s mental health—-or work productivity. A nationwide survey by Fertility Network UK reveals 1 in 3 facing infertility receives minimal employer support, thus fostering a workplace stigma. Conceivable is committed to normalizing IVF care, sparking a broader cultural discussion. Beyond the Silence: Addressing Workplace Fertility Issues During Mental Health Awareness Month 📌 Be sure to check out the article linked in the comments, and let us know what you think!

As we start the new year and continue building the automated future of IVF at Conceivable Life Sciences and as the healthcare world convenes at #JPM2024, I am reflecting on my conference highlight of 2023, Innovations in Reproductive Medicine 2030: Technologies in IVF, hosted by the Carlos Simon Foundation. I spent 3 days listening to some of the world’s most renowned thought leaders as they spoke about the future of IVF Technologies. Some key highlights: ✨Carlos Simón presented work from their stealth Premium Fertility, which is automating embryo transfer with a direct embryo transfer system incorporating live imaging, robotics, AI and microfluidics... ‘Don’t throw your embryos into a black box’ - or ‘One euploid embryo should result in one live birth’ ✨Charles Boorman of Harvard IVF gave an overview of how AI is embedded in every aspect of their lab workflow, from semen morphology grading to prediction of embryo implantation potential, and for assisting with cryopreservation decisions. ✨Jake Anderson Bialis of FertilityIQ shared data from a survey of one million women from the Fertility IQ community showed that up to 50% of patients found virtual consultations helpful, with most patients having to wait up to 5 weeks after a failed IVF cycle to see a doctor in person. He concluded that the combination care model of in-person and virtual care is essential. “Personal connection will still be critical, given success-rates are a ‘coin-flip’on the first IVF cycle.” Carlos Simón reflected on the future role of the multidisciplinary IVF Team in the automated IVF laboratory. IVF delivered more efficiently with digital tools, home monitoring and testing, and in automated laboratories will not only improve success rates but will grant clinicians more time to make better-informed decisions. The Fertility team will need to ‘re-invent’ in order to meet the demands of the millions of patients who will benefit from a technology-driven, and automated lower cost service. Simón’s summary on the future of IVF he envisions aligns with the model we are building at Conceivable. Our fully automated lab will create a better way of treating infertility, serving millions within the community who have been under-served for far too long. Carlos Simon Jake Anderson-Bialis Laura Rienzi Dr Helen O'Neill Prof. Zeev Shoham Giudice Linda Bart CJM Fauser Milton Leong Hadi Shafiee Carlos Simon Foundation for Research in Women's Health Charles Bormann PhD, HCLD Antonio Capalbo Luca Gianaroli Kelle Moley Craig Niederberger Denny Sakkas Dagan Wells Piotr Wygocki IVF-Worldwide #biotech #AI #automation #Fertility #RM2030

It’s wonderful to once again be part of the JPMorgan Healthcare Conference. The growth in the healthcare sector and, in particular, IVF and fertility care is astounding. For historical context, my co-founder (Alan Murray) and I highly recommend this insightful piece by David Sable. As you will learn, the automation innovation we at Conceivable Life Sciences are driving has been long in the making. We are at an obvious inflection, witness Conceivable (with our clinical partners) preparing to offer high quality IVF for “$15,000 No Baby No Fee.”