Drug Discovery News

Tumors constantly release fragmented DNA into the bloodstream. This DNA provides vital insights into cancer but is challenging to detect due to its fleeting presence and low concentration in the blood. Join us on September 19th at 1:00PM ET for a webinar with Shervin Tabrizi from the Broad Institute of MIT and Harvard! He’ll discuss his innovative approach to capturing even the smallest traces of cancer, enabling earlier detection and more effective monitoring. Register today: https://ow.ly/3y4j50ThRAh

The future of toxicology is bright with the integration of advanced technologies like spatial transcriptomics and AI. Learn how these innovations are shaping drug development and improving patient outcomes. Read the interview with Myrtle D. from Bristol Myers Squibb, here: https://ow.ly/ELKE50T9VP8

Zeynep Ilgın Kolabaş, PhD and her collaborators at Ludwig-Maximilians-Universität München discovered that the skull is much more than a brain helmet. Read more: https://ow.ly/lwoF50T1y8n

Researchers are trying out some pretty unexpected ways to get the heart to regenerate after a heart attack. Jens Tank at the German Aerospace Center (DLR) told Allison Whitten about his team’s work putting patients into the largest hypoxic chamber in the world. 🎧 Listen here: https://ow.ly/hylA50SXPs1

Dopamine is in various organs besides the brain, which might explain the systemic side effects of antipsychotics. University of Pittsburgh scientists reported that a modified version of bromocriptine stimulates dopamine receptors and may compete with antipsychotics that block dopamine signaling to address metabolic side effects. https://ow.ly/xBUE50TgzPS

The 2024 mpox outbreak involves a deadlier strain than the 2022 outbreak. Researchers developed an mRNA vaccine, mRNA-1769, which shows stronger protection than the traditional MVA vaccine and could improve responses to future outbreaks. https://ow.ly/OiNi50Thz25

“People think of statistics as just sitting at the computer and working on math and methods, but we're really motivated to develop these statistics to improve public health and save lives,” Rebecca Kahn at the Centers for Disease Control and Prevention told Stephanie DeMarco, PhD about her maternal GBS vaccine model. https://ow.ly/OG0e50TfCg2

Opioid overdose can be treated with naloxone. But for stimulant drug overdoses, there are no treatments. Allison Whitten spoke with researchers who are attempting to change that. https://ow.ly/2oZY50TeLim

What if paralysis due to spinal cord injury was a temporary condition, like a twisted ankle or broken bone? Jessica Liu and Martin Cheung lead a team at HKUMed – The University of Hong Kong that work on making this science fiction dream a reality. https://ow.ly/OfNG50TeKRu

Researchers at the Cleveland Clinic unveiled LRIG1 as a novel inhibitory receptor, interacting with VISTA to suppress T cell activity. This discovery might explain why some patients resist immunotherapies and could lead to new cancer therapies. https://ow.ly/tRTB50T9K3b