Forge Biologics

Where do I start, and will it work? With numerous development studies, scales, and grades of AAV available in planning manufacturing pathways to successfully reach program milestones, this common two-fold question remains consistent between developers and their manufacturing partners. Read our latest article in Endpoints News where Forge's Director of Technical Sales, Brianna Barrett, Ph.D., investigates two high-powered strategies that provide programs a foundation for success: 1. Building a program around robust analytics 2. Continuous re-evaluation of your manufacturing approach as data becomes available Read the full article, including case studies here: https://hubs.li/Q02Hq5VY0

Our Women’s ERG, SheForges had the opportunity to volunteer at Flying Horse Farms, a specialty camp that provides experiences at no cost for kids with serious illnesses to heal, grow, and thrive. The incoming campers are all affected by rare disease, a community we care about deeply and have built our mission around serving. Thank you to the volunteers for dedicating their time and talents to this incredible organization!

There are many paths to a biotech career, including pursuing a Ph.D. Forge's Blake E. Szkoda, PhD, Scientist I in Analytical Development, inspired our Ignite interns by sharing how a Ph.D. can unlock multiple career opportunities. Blake spoke about his Ph.D. application process, research projects, and answered questions from our interns interested in pursuing their own graduate degree. He even shared his thesis and one of his publications. A huge thanks to Blake for investing his time with our 2024 class!

💡 Meet Carla Sanguetin, our Senior Quality Systems Specialist! Carla shares insights about her role on the Quality Management team, how the Forge core value of "Hardworking" resonates with her, and a fun fact: she speaks to pets in Portuguese, her native language! Discover more about Carla and the amazing individuals who make our team unique ➡️ https://hubs.li/Q02GXZGr0

Forge is accelerating AAV manufacturing from discovery to delivery and every need in between. Our suite of scalable manufacturing services includes: • Plasmid Manufacturing • Research-Scale Manufacturing (1-40L) • Process Development (1-1,000L) • cGMP Manufacturing (50-5,000L) • >20 In-House Assays • Fill & Finish • Stability Learn more about our manufacturing capabilities here ➡️ https://hubs.li/Q02GPWNh0

🔦 July hiring spotlight! We are seeking a Client Relations Manager with industry experience to join our commercial team The Client Relations Manager position is responsible for building and maintaining strong, lasting relationships with our clients, ensuring their needs are met, and that they derive maximum value from our solutions. This position will require strong communication skills, a detail-oriented problem-solving mindset, and a commitment to providing exceptional client service. Forge is a team of diverse, driven, and passionate people working together to trailblaze a new model for how medicines are made to treat patients with genetic diseases. Learn more about the role here ➡️ https://bit.ly/4615L7a

“It’s saving our analysts countless hours...it’s saving my management team hours and driving a lot of benefits for our clients, who now have more visibility into their data and easier access to results.” Andrew Laughhunn, our Senior Director of Quality Control, recently spoke with Veeva Systems on how Vault LIMS is helping us scale our QC operations for rapid growth. Veeva Vault LIMS has allowed Forge to more effectively and efficiently manage client work through a unified digital platform. Read the full article here ➡️ https://bit.ly/462y9Wr

📰 Featured highlight! Our Chief Medical Officer Maria L Escolar, MD, MS, was recently interviewed by CGTLive about navigating the novel drug development journey for patients with Krabbe disease, a rare leukodystrophy, and the importance of newborn screening for rapid identification and treatment. Read more here ➡️ https://bit.ly/4bBmpva

Our quality-by-design HEK293 Ignition Cells™ and pEMBR™ Ad Helper Plasmid allow us to deliver more efficient services to gene therapy developers. Here's how 👇 Ignition Cells™: • Applicable across a wide variety of indications, serotypes, and stages of development • Well-documented history with regulatory feedback • Fully qualified Master Cell Bank and Working Cell Bank produced at Forge • >90% full capsid post-enrichment with CsCl, with undetectable empty particles • Used by >95% of clients pEMBR™ Ad Helper Plasmid: • Immediately available at research and phase I/II GMP-Pathway grades • Shows equivalent AAV yields as compared to commercially available alternatives • Improved safety profile, engineered to reduce known immunogenic elements • Decreased size increases efficiency in manufacturing • Used by >80% of clients

We’re hiring! Our award-winning culture and excellent benefits make Forge a standout workplace. We offer flexible PTO, paid parental leave, a flexible work environment, and more! We are a team of diverse, driven, and passionate people working together to trailblaze a new model for how medicines are made to treat patients with genetic diseases. Explore our open positions and start or continue your gene therapy career here ➡️ https://bit.ly/3xLdcTi