We collect information from mothers and their doctors to find out what medicines the mother used during pregnancy. We use data from computer models, cell lines and animal lactation studies to predict how medicines transfer to human milk. We collect information about children from mothers who used medicines during pregnancy, to see if there is any correlation between medicine use and malformations or effects on the development of the child. We also collect and analyse milk and blood from breastfeeding mothers who use particular medicines. We have also built a knowledge bank where women and doctors can find reliable information about how safe a medicine is. Want to know more about our work? Take a look at our website: https://lnkd.in/giVcXem #Pregnancy #Breastfeeding #MedicineSafety #ConcePTION
IMI ConcePTION
Research Services
Building a safety evidence ecosystem, because pregnant & breastfeeding women deserve to know if their medicines are safe
About us
ConcePTION aims to create a paradigm shift in how we generate and disseminate evidence on the effects of medication in pregnancy and breastfeeding. The ConcePTION project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 821520. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA.
- Website
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https://www.imi-conception.eu/
External link for IMI ConcePTION
- Industry
- Research Services
- Company size
- 51-200 employees
- Type
- Nonprofit
- Founded
- 2019
Employees at IMI ConcePTION
Updates
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IMI ConcePTION reposted this
The last but not least day of #ISPEAnnual2024 - International Society for Pharmacoepidemiology 1️⃣ Oral presentation of a collaborative work IMI ConcePTION by Anna Girardi describing the impact of data source diversity on the distribution of key variables in pregnancy cohorts based on the ConcePTION pregnancy algorithm leveraging a random forest imputation model. 2️⃣ Nicolas Thurin (Bordeaux PharmacoEpi - Université de Bordeaux) will moderate with Prof. Dr. Dorothee B. Bartels the very interesting session of oral presentations about COVID-19: Now and Later.
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IMI ConcePTION reposted this
🔬 Are you interested in exploring both non-clinical and clinical approaches to determine secretion of medicines in breast milk? 🔍 Check out Pieter Annaert's presentation on the ConcePTION project's tools and approaches to study how medicines transfer to breast milk using in vitro, in vivo, in silico, and clinical approaches. 🎥 The presentation was featured in the LifeSaver Project & IMI ConcePTION joint webinar “Joining forces to improve maternal health & pregnancy pharmacovigilance". 👉 Watch the presentation here: https://lnkd.in/dnSdabkd
Are you interested in non-clinical & clinical approaches to determine secretion of medicines in breast milk? Take a look at this presentation by Pieter Annaert, where he presents the ConcePTION project’s tools and approaches to study how medicines transfer to breast milk, using in vitro, in vivo, in silico and clinical approaches. This presentation was part of the LifeSaver Project & IMI ConcePTION joint webinar “Joining forces to improve maternal health & pregnancy pharmacovigilance“ earlier this year. Watch the presentation here 👉 https://lnkd.in/dnSdabkd
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Are you interested in non-clinical & clinical approaches to determine secretion of medicines in breast milk? Take a look at this presentation by Pieter Annaert, where he presents the ConcePTION project’s tools and approaches to study how medicines transfer to breast milk, using in vitro, in vivo, in silico and clinical approaches. This presentation was part of the LifeSaver Project & IMI ConcePTION joint webinar “Joining forces to improve maternal health & pregnancy pharmacovigilance“ earlier this year. Watch the presentation here 👉 https://lnkd.in/dnSdabkd
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IMI ConcePTION reposted this
🤰 DYK IMI project IMI ConcePTION has developed recommendations to optimise the way we collect, analyse and report data on medicine use during #pregnancy? 💊 This will speed up efforts to assess the risks of taking different medicines while pregnant. 🌞 https://europa.eu/!9mmFCC #IHISummerOfScience #HorizonEU
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There is a huge knowledge gap on medicine safety in pregnancy and breastfeeding. Only 3.7% of available drugs are explicitly labeled as safe and information is often inconsistent and difficult to find and understand. The Innovative Health Initiative (IHI) ConcePTION project is developing an ecosystem to develop evidence on #MedicineSafety in #Pregnancy and #Breastfeeding. Visit our website to read more about our work: https://lnkd.in/giVcXem
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A recent study in the British Journal of Clinical Pharmacology is providing reassurance regarding the use of sertraline during pregnancy and breastfeeding. Sertraline is used to manage several mental health conditions, and it is frequently prescribed during pregnancy and breastfeeding. The IMI ConcePTION project has developed a population pharmacokinetic (popPK) model to describe how the body interacts with the drug during pregnancy and breastfeeding. – Our results are in line with previous studies, and show that infant exposure is low, which is reassuring, as sertraline is widely used during pregnancy and breastfeeding, says Anaëlle Monfort, PhD student at the Université de Montréal’s Faculty of Pharmacy, and one of the authors of the recent publication. Do you want to know more? Read the news article on our website: https://lnkd.in/dxbSi-VC Innovative Health Initiative (IHI)
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Do you want to learn about our work on building an ecosystem for medicine safety in pregnancy and breastfeeding? Take a look at this presentation by Miriam Sturkenboom, coordinator and Marjolein Willemen, MSc, PharmD, PhD, project leader for the IMI ConcePTION project about the project’s contribution to a European ecosystem for medicine safety in pregnancy and breastfeeding. This presentation was part of the LifeSaver Project and IMI ConcePTION joint webinar “Joining forces to improve maternal health & pregnancy pharmacovigilance“ this spring. Watch the presentation here 👉 https://lnkd.in/d3tc3Txr
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Did you know that 9 of 10 women use at least one medicine at some stage during pregnancy? Pregnant women sometimes need to take medicines. Sometimes the reason has nothing to do with pregnancy. Sometimes health problems start in pregnancy and sometimes women take medicines before they know that they are pregnant. Often there is not enough evidence to provide trustworthy information about a particular drug might affect the fetus. The Innovative Health Initiative (IHI) ConcePTION project is developing an ecosystem to study medicine safety in pregnancy and breastfeeding. #Pregnancy #Breastfeeding #MedicineSafety #ConcePTION
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IMI ConcePTION reposted this
Professor of Interprofessional Primary Care - Pharmacy vision at Institute of Primary Health Care (BIHAM), University of Bern, Switzerland
A new proof of concept study showcasing how population pharmacokinetic approaches can contribute to prediction of infant exposure to medication via breast milk using clinical samples gathered through sparse sampling (i.e. convenient for breastfeeding persons) as well as to identification of risk factors for higher infant exposure. ✅ Infant exposure to sertraline, influenced by CYP2C19 phenotype and breast milk fat content, remains low, providing reassurance regarding the use of sertraline during breastfeeding. 🙏🏿 Thank you to all our colleagues that have contributed to this important effort for breastfeeding patients. Anaëlle Monfort Evelina Cardoso Eap Chin-Bin Nicolas Ansermot Severine Crettol Céline Fischer Miriam Bickle Mathilde Morisod Etienne Weisskopf Peggy GANDIA karel allegaert Pieter Annaert Hedvig Marie Nordeng Jean-Michel HASCOET Olivier CLARIS Manuella Epiney Ferreira Ema Grégoire Leclair Chantal Csajka Monia Guidi and all the collaborators of the SSRI milk study. 🔗As you see, it takes more than one collaboration to implement new ways to increase knowledge in medication safety in breastfeeding. 🛜 Stay tuned, more is coming through the IMI ConcePTION project with Miriam Sturkenboom BIHAM Institute of Primary Health Care CHUV / Centre hospitalier universitaire vaudois #breastfeeding #popPK #medicationsafety #specialpopulation European Medicines Agency #FDA #ENTIS
BPS Publications
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