MyFitStrip

MyFitStrip LLC was officially awarded a patent on improving Nitric Oxide (NO) to reduce symptoms of Covid and respiratory infections by the US Patent & Trademark Office. Airway and oral Nitric Oxide provides a major innate defense against such respiratory infections.  Unfortunately, Nitric Oxide production is compromised during infection, especially observed among Covid patients. A growing body of evidence continues to show that boosting nitric oxide bioavailability locally in the oral cavity may be beneficial in protection from such infections. Saliva is reservoir for Covid and contributes to transmission.  And the clinical presentation of Covid-19 begins in the mouth and oral nasopharynx resulting in acute respiratory distress in the lungs that moves quickly to vascular networks with associated endothelial dysfunction. CoV-2 has emerged as a vascular disease targeting endothelial cells throughout the body and is particularly evident in patients with cardiometabolic comorbidities. A hallmark of endothelial dysfunction is suppressed endothelial nitric oxide synthase with concomitant nitric oxide deficiency. Dietary inorganic nitrate formulas have been shown in multiple studies to be effective at restoring endothelial function and promoting antimicrobial activity. It is well understood that dietary prebiotic inorganic nitrate (NO3) formula bio-converted to nitric oxide through a series of well-defined steps beginning with a community of nitrate-reducing bacteria in saliva which is subsequently reduced to nitric oxide in the gut and blood stream, including the lung. USPTO awarded patent also highlights the point-of-assessment of MyFitStrip's next generation NO test strips. Evidence suggests that low nitrite (NO2−), low NO2−/NO3− and high NO3− may be potential biomarkers of long-term poor or irreversible outcomes after SARS-CoV-2 infection. Saliva NO metabolites are emerging to be predictor to track the health status of recovered COVID-19 patients. As we continue to work on new approaches to restore NO bioavailability, the US Patent Office awarded MyFitStrip for both assessing salivary NO metabolites and improving nitric oxide levels with a composition comprising chewable gummies dietary prebiotic nitrate and vitamin C for improving outcomes with SARS and a means to enhance nitric oxide bioavailability to hopefully keep such infections at bay. And remember saliva is a primary reservoir and means of transmission. So, another reason to ensure a healthy nitric oxide-promoting oral microbiome for both oral and systemic well-being. https://lnkd.in/gvE8JYtn #nitricoxide #covid #rsv #flu  #oralhygiene #respiratoryhealth #food #health #healthcare #dietarysupplements  #consumerhealth #oralhealth #testing #microbiome  #cardiovasculardisease #covid19  #functionalnutrition #cardiovascularhealth #brainhealth #alzheimers #dementia 

Another reason why prebiotic inorganic nitrate should be incorporated into your diet?

Excited to officially share what we have been working on - the tool we we wish we had at Webflow and Notion. For years, Tim D. and I dealt with the problems we are solving on a daily basis: - Tough to track & model the right metrics - and attribute customers correctly - Can’t get access to right data, when you need it - Analysis to figure out what to do to drive impact takes a ton of time & expertise This is just the beginning - our goal is to enable growth marketing teams to operate like data-driven investment managers, with the confidence that resources are allocated across the best portfolio of growth opportunities specific to their business. Learn more here: https://lnkd.in/eW9dd3Dc If you want Roadway for your team you can join the waitlist or reach out directly: roadwayai.com We’re also on Product Hunt today (thanks Ben Lang!): https://lnkd.in/eCJYEqTr

This article highlights all the benefits of MyFitStrip's nitric oxide functional gum product. The NO gum is the only product available that efficiently generates nitric oxide because: - the gum creates is own favorable oral microbiome ( ⬆ good, commensal bacteria and ⬇ bad, pathogenic bacteria), and, - the gum uses its own source of nitrates delivered directly into the oral cavity and is not dependent on the traditional, inefficient NO pathway through the digestive tract and salivary glands (only 25% comes through). No other nitric oxide product has both of these requirements for efficient generation of nitric oxide that the body can utilize to help improve overall health. #nitricoxide

New research published in the journal Nature has found a possible link between a type of bacteria found in dental plaque and a treatment-resistant form of colorectal cancer. Fusobacterium nucleatum, commonly found in the mouth and linked to gum disease and plaque buildup, appears to shield tumor cells from cancer-fighting drugs and was present in 50% of the tumors tested. While this discovery could pave the way for new treatment strategies, experts recommend keeping this bacteria at bay and in low numbers in the mouth. It's also worth noting that this bacterium is nitric oxide sensitive as described in MyFitStrip’s patents. Keep those oral nitric oxide level elevated… learn more at: https://lnkd.in/ggMuWBym #nitricoxide #microbiome #oralhealth #consumerhealth #cancer #dental #functionalnutrition #functionalmedicine #nutrition #oralhygiene #diet #dietarysupplements #consumerhealthcare #health

To improve oral health outcomes, you can chew a serving of a leafy green salad or a piece of MyFitStrip’s leafy green plant-made chewy gum. Leafy green fruit smoothies are great, but don’t underestimate the importance of chewing your leafy greens and fruits. MyFitStrip’s patented plant-based prebiotic chewing gum formula is designed to extend the ‘hang time’ or residence of the plant-derived bioactives in the mouth to optimize oral health. … and a healthy mouth is a healthy heart. Learn more on why and visit www.myfitstrip.com: #prebiotics #nitricoxide #oralhealth #microbiome #consumerhealth #dental #plantbased #ukhealthcare #consumerbehavior #oralhygiene #foodasmedicine #functionalnutrition #functionalmedicine #veganfood #vegetables #wholefoods #cpg #neurohealth #health #brainhealth #eyehealth #consumerinsights #hearthealth #gumdisease #periodontaldisease #dentalinnovation #cardiovascular #ushealthcare #dietarysupplements #toothpaste #training #aarp #longevity #sportsmedicine #ageing #biofilm #integrativemedicine #preventivemedicine

A recent clinical study showed the combination of inorganic dietary nitrate and a hydrogen sulfide source from garlic, S-allylcysteine (SAC), robustly reduced both systolic and diasystolic blood pressure by ~11 mmHg in 2 weeks and persisted beyond 4 with daily administration in mild hypertensive.  With no noticeable reduction in normotensive.  Further, salivary nitric oxide as demonstrated by MyFitStrip's PREBIOTIC NITRIC OXIDE SALIVA TEST STRIPS revealed high peak levels at two hours post-administration and a slow decay to elevated levels at 24 hours. Nitric oxide bioavailability remained above baseline for the duration of the study.  Hydrogen sulfide and nitric oxide are strikingly similar in so many ways: both are reactive, short-lived gases, nearly the same small molecular weight, synthesized naturally in the body, often by the same cells within the same organs, and exert many of the same biologically beneficial properties: both are anti-inflammatory, antioxidant, and effective vasodilatory agents. Furthermore, we loss the ability to make these two vital gases with advancing age hence, dietary sources are critical. The extended nitric oxide bioavailability shown in this study by MyFitStrip may be credited to the presence of black garlic-derived, SAC, which, as a dietary source of hydrogen sulfide, is expected to amplify eNOS activation and nitric oxide synthesis through both the canonical (L-arginine-dependent) and non-canonical (dietary nitrate) pathways, to maintain elevated levels of cGMP, and to possibly combine with nitric oxide to form stable intermediates, S-nitrosothiols, that serve as nitric oxide stores. Our work at MyFitStrip believes that endothelial dysfunction may be impairment of BOTH vascular nitric oxide and hydrogen sulfide (since the synthesis of both gases are reduced naturally as we age), therefore, supplementation of either alone will emerge to be inadequate to restore vascular homeostasis. Therefore product strategies and precursor formulation for nitric oxide and hydrogen synthesis should consider simultaneous restoration of both nitric oxide and hydrogen sulfide. And enhance this response by maintaining a healthy oral microbiome enriched with nitric oxide-promoting commensal bacteria with MyFitStrip’s patented NITRIC OXIDE FUNCTIONAL CHEWING GUM. Stay fit with MyFitStrip’s Saliva Test Strips and Functional Chewing Gum. #health #functionalnutrition #plantbased #functionalmedicine #cardiovascularhealth #aarp #ageism #ageing #womenhealth #longevity #consumerinsights #consumerhealth #consumerhealthcare #hypertension #t2d #inflammation #bloodpressure #diet #microbiome #prebiotic #selftest #selfcare #testing #vascularhealth #cardiovascular #diet #food #cpg #dietarysupplements #covid #nitricoxide #preventivemedicine #garlic #hydrogensulfide #brainhealth #memory #alzheimers #vascularhealth #dementia

Thank you Shawn J. Green for sharing this excellent piece. Just to add to this great post. In India, those companies who claim they are reversing #type2diabetes, without decoding, measuring & analysing #chronicinflammation , endothelial cell dysfunction, production of Nitric Oxide by Nitric Oxide Synthase &/or via oral microbiome through nitrate- nitrite conversion cycle , are just one more added misery to healthcare sector & do not have even an iota of understanding cellular communication & insulin signalling on onset & progression of #type2diabetes All those #VCfund investing in these companies are contributing to pain & misery of patients. I think #healthcare in India has a long way to catchup to understand the real underlying cause of these growing chronic diseases. Such investments are just pushing healthcare sector back to primitive age. Healthcare has to be driven by personalised approach considering various factors including microbiome , rather these new age VC funded startups have made healthcare nothing more than a FMCG sector. #gutmicrobiome #oralhealth #acidreflux #biotech #healthcare #healthcareinnovation Sakshi Bali Shashi Shekhar M. Tarun Kumar Dr Kamal Karnatak Rupinder Singh