“Devon was a student in a lab that I taught. He had quite a high-level understanding of each experiment he was working on. His diligence and hard work made him a stellar student in my class.”
Devon Cayer
San Diego County, California, United States
4K followers
500+ connections
About
My entrepreneurial philosophies --
1. Always push the boundaries of what is…
Contributions
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How can you optimize nanomaterial surface area for catalytic applications?
Another method would be thinking of the chemistry of the reaction, and how reactants are reacting with the catalytic components at low concentration if the materials are precious. Borrowing insights from biology, it is possible to enhance avidity with polymeric materials to help transport and funnel reactants towards catalytic regions. This will aid to drive materials out of solution and back into the bulk environment after catalysis. Careful design of polymeric properties and screening of materials will allow for the materials to be developed. First begin with a control reaction in idealized conditions, then slowly make the environment or conditions more strict as optimization of the material improves.
Activity
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Exciting news from Truvian! I'm proud to share that we've secured $74 million in funding to accelerate the launch of our innovative #BloodTesting…
Exciting news from Truvian! I'm proud to share that we've secured $74 million in funding to accelerate the launch of our innovative #BloodTesting…
Liked by Devon Cayer
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Agree with Abhishaike Mahajan “While computation alone may have delivered the first fundamental advance in ML in biology, I believe it will not be…
Agree with Abhishaike Mahajan “While computation alone may have delivered the first fundamental advance in ML in biology, I believe it will not be…
Liked by Devon Cayer
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The 2nd Quarterly San Diego Proteomics Happy Hour was a great success! We were glad to see so many proteomics practitioners in the San Diego area…
The 2nd Quarterly San Diego Proteomics Happy Hour was a great success! We were glad to see so many proteomics practitioners in the San Diego area…
Liked by Devon Cayer
Experience
Education
Publications
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An enzyme-free, kinetically controlled, isothermal method for the “digital” detection of single nucleotide mismatches
Bioorganic & Medicinal Chemistry Letters
We describe an isothermal, enzyme-free method to detect single nucleotide differences between oligonucleotides of close homology. The approach exploits kinetic differences in toe-hold-mediated, nucleic acid strand-displacement reactions to detect single nucleotide polymorphisms (SNPs) with essentially “digital” precision. The theoretical underpinning, experimental analyses, predictability, and accuracy of this new method are reported. We demonstrate detection of biologically relevant SNPs and…
We describe an isothermal, enzyme-free method to detect single nucleotide differences between oligonucleotides of close homology. The approach exploits kinetic differences in toe-hold-mediated, nucleic acid strand-displacement reactions to detect single nucleotide polymorphisms (SNPs) with essentially “digital” precision. The theoretical underpinning, experimental analyses, predictability, and accuracy of this new method are reported. We demonstrate detection of biologically relevant SNPs and single nucleotide differences in the let-7 family of microRNAs. The method is adaptable to microarray formats, as demonstrated with on-chip detection of SNP variants involved in susceptibility to the therapeutic agents abacavir, Herceptin, and simvastatin.
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Mission critical: the need for proteomics in the era of next-generation sequencing and precision medicine
Human Molecular Genetics
Review covering the current state of multiplex proteomics.
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A modular and general Inhibitor-DNA-Enzyme (IDE) architecture for the isothermal, sequence-specific detection of oligonucleotides
UMI
Thesis Work: "Programmable biomolecules and their applications in diagnostics and therapeutics"
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Prediction of microRNA targets by evoking the endogenous microRNA target-site protection paradigm
UMI
Thesis Work: "Programmable biomolecules and their applications in diagnostics and therapeutics"
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Small molecule-DNA and antibody-DNA directed recruitment of an oligonucleotide regulated enzyme for selective cytotoxicity against tumor cell lines
UMI
Thesis Work: "Programmable biomolecules and their applications in diagnostics and therapeutics"
Patents
Honors & Awards
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Indiebio Accelerator Batch 2
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One of 14 biotech start-up companies selected to build a company in San Francisco for 4 months. Company, MYi Diagnostics and Discovery, received a 250K award for the program.
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Illumina Sequencing Grant
Illumina Accelerator
Upon being a finalist in the Illumina Accelerator Spring 2015 competition, was awarded an Illumina Sequencing Grant to aid in the development of MYi technology.
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Accepted in Y-Combinator S19 Batch
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Did not accept offer due to in-progress fundraise
Languages
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French
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Spanish
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Recommendations received
2 people have recommended Devon
Join now to viewMore activity by Devon
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I'm excited to announce that I'll be chairing the Neurotech track at SynBioBeta 2025, May 5-8, 2025! I am looking forward to collaborating on…
I'm excited to announce that I'll be chairing the Neurotech track at SynBioBeta 2025, May 5-8, 2025! I am looking forward to collaborating on…
Liked by Devon Cayer
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We're building an AI Research Assistant at Potato. It can now plan and run computational experiments - see demo video 🤯 Reach out if you want to…
We're building an AI Research Assistant at Potato. It can now plan and run computational experiments - see demo video 🤯 Reach out if you want to…
Liked by Devon Cayer
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It’s been great to work with Aditya Ghosh and others on leveraging GOSTAR data in our model building activities. Highly recommended!
It’s been great to work with Aditya Ghosh and others on leveraging GOSTAR data in our model building activities. Highly recommended!
Liked by Devon Cayer
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If there are founders that (••) sense "intelligence is the efficiency with which a learning system turns experience and priors into skill at…
If there are founders that (••) sense "intelligence is the efficiency with which a learning system turns experience and priors into skill at…
Liked by Devon Cayer
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🥇 Last week, I won a GOLD medal in a Kaggle competition of Leash Bio, placing 8th out of around 2000 teams! This was my second competition in the…
🥇 Last week, I won a GOLD medal in a Kaggle competition of Leash Bio, placing 8th out of around 2000 teams! This was my second competition in the…
Liked by Devon Cayer
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Very excited to announce this. We have been planning this for a few years now. Hope to see you there!
Very excited to announce this. We have been planning this for a few years now. Hope to see you there!
Liked by Devon Cayer
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Every one of my friends and colleagues should watch the Neuralink update. You will learn a lot. But also, just think about what Elon managed to…
Every one of my friends and colleagues should watch the Neuralink update. You will learn a lot. But also, just think about what Elon managed to…
Liked by Devon Cayer
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Our philanthropy team at Scripps Research is hiring! If you are interested or know of anyone who is highly motivated and passionate about making a…
Our philanthropy team at Scripps Research is hiring! If you are interested or know of anyone who is highly motivated and passionate about making a…
Liked by Devon Cayer
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