Betsy Mulé

Betsy Mulé

United States
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Experience

  • F-Prime Capital Graphic

    F-Prime Capital

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    United States

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    Boston, Massachusetts, United States

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    Greenwich, Connecticut

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    Greenwich, CT

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    Taoyuan County, Taiwan/Tsing Yi Island, Hong Kong

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    Cambridge, Massachusetts, United States

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    Cambridge, MA

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    Greenwich, CT

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    Nicotera, Italy

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    St. Louis, MO

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Education

Volunteer Experience

Publications

  • A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment

    Science Translational Medicine

    Although Mycobacterium tuberculosis (TB) infections are effectively treated with antibiotics, treatment requiring multigram dosing can pose considerable challenges for patients in resource-constrained environments. Here, Verma et al. developed a drug delivery system that is compatible with nasogastric administration consisting of bead-like drug pills on a shape memory wire that resides in the stomach for long-term, multigram dosing. The device was administered to healthy pigs where it…

    Although Mycobacterium tuberculosis (TB) infections are effectively treated with antibiotics, treatment requiring multigram dosing can pose considerable challenges for patients in resource-constrained environments. Here, Verma et al. developed a drug delivery system that is compatible with nasogastric administration consisting of bead-like drug pills on a shape memory wire that resides in the stomach for long-term, multigram dosing. The device was administered to healthy pigs where it demonstrated safe, sustained antibiotic release within the stomach over weeks; it was also easily retrieved from the stomach when drug delivery was complete. The authors suggest that this device could improve patients’ adherence to treatment regimens.

    See publication

  • A Linear Relationship between Crystal Size and Fragment Binding Time Observed Crystallographically: Implications for Fragment Library Screening Using Acoustic Droplet Ejection

    See publication

Organizations

  • Sigma Kappa Sorority

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    - Present

  • Engineers Without Borders

    Project Leader

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    •Led a team of 12 in developing innovative charcoal burning techniques for the Rumuruti village in Kenya. Organized team meetings and maintained communication with leaders of the village •Traveled to Domasi, Malawi to perform assessments on and form community ties with the Joyce Banda Foundation Secondary School for Orphans for future work with MIT EWB

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