Farhad (Seyyedhassan) Paylakhi

Farhad (Seyyedhassan) Paylakhi

United States
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Experience

  • 64x Bio Graphic

    64x Bio

    San Francisco

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    Novato, California, United States

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    San Francisco Bay Area

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    San Diego, California, United States

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    Novato

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    Iran

Education

  • Tarbiat Modares University Graphic

    Tarbiat Modares University

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    • Developed a siRNA-based strategy to identify targets of FOXC1 and PITX2 transcription factors in primary human TM cells using microarray analysis, hence initiated a new area of research in a Human Genetics lab.

    • Identified genetic mutations responsible for both glaucoma and Weill-Marchesani syndrome by working with a multidisciplinary team of physicians, human geneticists, and basic scientists.

    • Designed, performed and interpreted all of the molecular and cellular…

    • Developed a siRNA-based strategy to identify targets of FOXC1 and PITX2 transcription factors in primary human TM cells using microarray analysis, hence initiated a new area of research in a Human Genetics lab.

    • Identified genetic mutations responsible for both glaucoma and Weill-Marchesani syndrome by working with a multidisciplinary team of physicians, human geneticists, and basic scientists.

    • Designed, performed and interpreted all of the molecular and cellular experiments to demonstrate the functional importance of the LTBP2 gene.

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Licenses & Certifications

Publications

  • Multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci

    Nature Communications

    See publication

  • Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error

    PLOS GENETICS

    See publication

  • Comparing the Effect of Silybin and Silybin Advanced™ on Viability and HER2 Expression on the Human Breast Cancer SKBR3 Cell Line by no Serum Starvation

    Iran J Pharm Res

  • MicroRNAs Signature in IL-2-Induced CD4+ T Cells and Their Potential Targets

    Biochem Genet

  • MIR184 Mutations Not Observed in 47 Iranian Keratoconus Patients

    J Ophthalmic Vis Res

  • Silibinin, Up-regulates Chemokine Receptor Expression in MDA-MB-231 Breast Cancer Cell Line

    Bangladesh Journal of Medical Science

  • cAMP Pathway Modifies Memory Through NCAM Alterations in the Rat Hippocampus

    Acta Med Iran

  • The Comparison of Silybin and Silybin-phosphatidylcholine Effects on Viability, ESR1 and ESR2 Expression in Human Breast Cancer T47D Cell Line

    Cell J

  • FOXC1 in Human Trabecular Meshwork Cells is Involved in Regulatory Pathway that Includes miR-204, MEIS2 and ITGβ1

    Exp Eye Res

  • LTBP2 Mutations Cause Weill-Marchesani and Weill-Marchesani-Like Syndrome and Affect Disruptions in the Extracellular Matrix

    Hum Mutat

  • MicroRNA Signature Associated with Chondrocite Lineage Commitment

    J Gnetics

  • MicroRNA Signature Associated with Osteogenic Lineage Commitment

    Mol Biol Rep

  • Non-housekeeping Genes Expressed in Human Trabecular Meshwork Cell Cultures

    Mol Vis

  • Effect of PITX2 Knockdown on Transcriptome of Primary Human Trabecular Meshwork Cell Cultures

    Mol Vis

  • Loss of Function Mutations in the Gene Encoding Latent Transforming Growth Factor Beta Binding Protein 2, LTBP2, Cause Primary Congenital Glaucoma

    Hum Mol Genet

  • Variable Expressivity and High Penetrance of CYP1B1 Mutations with Respect to Glaucoma

    Ophthalmology

  • Screening of Common CYP1B1 Mutations in POAG Patients Using a Microarray-based PrASE Protocol

    Mol Vis

Honors & Awards

  • KTEF Career-Starter Research Grant

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    Title: Genetic Determinants of the Postnatal Regulation of the Ocular Size

  • Sek-Jin Chew Travel Grant, The Association for Research in Vision and Ophthalmology (ARVO)

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  • The Second Best Article Award in Basic Medical Sciences, The Iranian Academy of Medical Sciences Award

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  • The Best Dissertation Award, The Second Annual Meeting of the Iranian Research Association for Vision & Ophthalmology (IRAVO)

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  • The Second Laureate, Fundamental Research Award, 23rd Khwarazmi International Award (KIA)

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  • Ranked 9th in Biological Sciences, The National Scientific Olympiad for University Students

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  • Ranked 7th in Molecular Genetics, The National Entrance Exam for M.S. Studies

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Languages

  • English

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  • Persian (Farsi)

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Organizations

  • ARVO

    No

    - Present

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