George Church
Boston, Massachusetts, United States
6K followers
500+ connections
Activity
-
https://lnkd.in/eiybv8kU
https://lnkd.in/eiybv8kU
Shared by George Church
-
I am thrilled to share that I just received the Outstanding Career Achievement Award from Tufts University School of Engineering. It is a profound…
I am thrilled to share that I just received the Outstanding Career Achievement Award from Tufts University School of Engineering. It is a profound…
Liked by George Church
-
https://lnkd.in/e8xQ_fBM
https://lnkd.in/e8xQ_fBM
Shared by George Church
Licenses & Certifications
Volunteer Experience
-
volunteer
openhumans.org
- Present 18 years 8 months
Science and Technology
Publications
-
Concerning RNA-Guided Gene Drives for the Alteration of Wild Populations
eLife
Gene drives may be capable of addressing ecological problems by altering entire
populations of wild organisms, but their use has remained largely theoretical due to technical
constraints. Here we consider the potential for RNA-guided gene drives based on the CRISPR
nuclease Cas9 to serve as a general method for spreading altered traits through wild populations
over many generations. We detail likely capabilities, discuss limitations, and provide novel
precautionary strategies to…Gene drives may be capable of addressing ecological problems by altering entire
populations of wild organisms, but their use has remained largely theoretical due to technical
constraints. Here we consider the potential for RNA-guided gene drives based on the CRISPR
nuclease Cas9 to serve as a general method for spreading altered traits through wild populations
over many generations. We detail likely capabilities, discuss limitations, and provide novel
precautionary strategies to control the spread of gene drives and reverse genomic changes. The
ability to edit populations of sexual species would offer substantial benefits to humanity and the
environment. For example, RNA-guided gene drives could potentially prevent the spread of
disease, support agriculture by reversing pesticide and herbicide resistance in insects and
weeds, and control damaging invasive species. However, the possibility of unwanted ecological
effects and near-certainty of spread across political borders demand careful assessment of each
potential application. We call for thoughtful, inclusive, and well-informed public discussions to
explore the responsible use of this currently theoretical technology.Other authorsSee publication -
Regulating gene drives
Science
Provides a regulatory, environmental, and security risk analysis of gene drives.
Other authorsSee publication
Languages
-
Spanish
Elementary proficiency
-
Fortran
Professional working proficiency
-
Python
Professional working proficiency
-
Esperanto
Elementary proficiency
More activity by George
-
Today marks an exciting day for BioLoomics, which is officially coming out of stealth! Our $8.7M seed round, led by Joel Dudley at Innovation…
Today marks an exciting day for BioLoomics, which is officially coming out of stealth! Our $8.7M seed round, led by Joel Dudley at Innovation…
Liked by George Church
-
ShapeTX is grateful to be able to participate once again in the Fred Hutch Obliteride. The Obliteride is an event that unites people of all ages…
ShapeTX is grateful to be able to participate once again in the Fred Hutch Obliteride. The Obliteride is an event that unites people of all ages…
Liked by George Church
-
https://lnkd.in/e8SqS5h
https://lnkd.in/e8SqS5h
Shared by George Church
-
At Plex we're putting all the world's biomedical research data behind one simple search bar. Check out our new web site to learn more:…
At Plex we're putting all the world's biomedical research data behind one simple search bar. Check out our new web site to learn more:…
Liked by George Church
Explore collaborative articles
We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
Explore MoreOthers named George Church in United States
-
George Church
Senior Talent Acquisition Specialist at Blue Chip Talent
-
George Church
Digital Marketing | E-Commerce | Brand Management
-
George Church
Genetics Professor at Harvard University
-
George Church
Principal at Miles & Stockbridge, P.C.
40 others named George Church in United States are on LinkedIn
See others named George Church