“I had the pleasure of working closely with Dr. Ramos at the University of Washington. Hilario brought an deep immunology background to the laboratory and was able to quickly apply it to the virology and innate signaling projects in house. He rapidly acquired the skills and expertise needed to succeed and generate novel projects. Dr. Ramos is a detail oriented and diligent scientist, a willing mentor, and an excellent asset to have in any group.”
About
Innovative immunologist with 10+ years’ experience in immune modulation and therapeutic…
Activity
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#DYK approximately 50% of people with initial symptomatic genital herpes infection have three or more recurrences per year? We’re aiming to develop…
#DYK approximately 50% of people with initial symptomatic genital herpes infection have three or more recurrences per year? We’re aiming to develop…
Liked by Hilario J. Ramos
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So excited to share the news of our recent IND approval!!
So excited to share the news of our recent IND approval!!
Liked by Hilario J. Ramos
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RiverVest is proud to support the work that Bluejay Therapeutics is doing for patients with chronic hepatitis B and hepatitis D.
RiverVest is proud to support the work that Bluejay Therapeutics is doing for patients with chronic hepatitis B and hepatitis D.
Liked by Hilario J. Ramos
Experience
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Education
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Activities and Societies: Longhorn Band
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Publications
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IL-1β signaling Promotes CNS-intrinsic Immune Control of West Nile virus Infection
PLOS Pathogens
IL-1 beta is a important cytokine involved in pro-inflammatory responses to infection. In this study, we identify a role for IL-1 beta in promoting immunity against flavivirus infection in vivo. In particular, we identify a novel role for IL-1 beta in the antiviral cross-talk with type I Interferon that leads to control of West Nile virus infection in the central nervous system.
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The RIG-I-like Receptor LGP2 Controls CD8(+) T Cell Survival and Fitness
Immunity
CD8+ T cells play a critical role in immunity to intracellular infection. Likewise, the RIG-I-like receptor family member, LGP2, has been shown to participate in innate immune control of viral and bacterial infection. In this study, we identify a novel role for LGP2 in bridging in innate and adaptive immunity. Here, we have found that LGP2 acts in a CD8+ T cell-intrinsic manner to control cell fitness and survival and that this is dependent on regulation of FAS signaling pathway.
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RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity
Current Opinions in Virology
Viruses trigger multiple host immune control response to elicit immunity. In this review, we focus on how the RNA sensing pathway of the RIG-I-like receptors cross-talks with other immune control pathways to promote optimal immune control of viral infection and how viruses have evolved mechanisms to antagonize these responses.
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Languages
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English
Native or bilingual proficiency
Recommendations received
1 person has recommended Hilario J.
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At Assembly, we are focused on developing innovative treatments for serious viral diseases, including hepatitis B and D. This #WorldHepatitisDay, we…
At Assembly, we are focused on developing innovative treatments for serious viral diseases, including hepatitis B and D. This #WorldHepatitisDay, we…
Liked by Hilario J. Ramos
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