“Khushboo and I met through our advisors in graduate school and I am happy that I got the opportunity to do so. She is a great colleague to work with. Her attention to details and commitment to work ensured she had a very productive time while at VCU. Khushboo is fast and effective in the lab; she has a great sense of understanding of her work and has the patience to teach others to do same. I would recommend her without any reservation at all”
Activity
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From Vision to Impact: CS4All in Kenya 🇰🇪 This summer, I had the incredible opportunity to bring our nonprofit, CS4All, to Kenya in partnership…
From Vision to Impact: CS4All in Kenya 🇰🇪 This summer, I had the incredible opportunity to bring our nonprofit, CS4All, to Kenya in partnership…
Liked by Khushboo Sharma
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I am excited and honored for the opportunity to host a HubXchange roundtable discussion with leading pharmaceutical industry experts! 🧬 We’ll be…
I am excited and honored for the opportunity to host a HubXchange roundtable discussion with leading pharmaceutical industry experts! 🧬 We’ll be…
Liked by Khushboo Sharma
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Join us at the AI in Drug Discovery Xchange 2024 roundtable discussion: Applying Genomic Data Analytics for Personalized Drug Response Prediction 🔬…
Join us at the AI in Drug Discovery Xchange 2024 roundtable discussion: Applying Genomic Data Analytics for Personalized Drug Response Prediction 🔬…
Liked by Khushboo Sharma
Experience
Education
Publications
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Poly (ethylene glycol)-armed hyperbranched polyoxetanes for anticancer drug delivery.
Journal of Bioactive and Compatible Polymers
A facile method for synthesis of polyethylene glycol (PEG)-armed hyperbranched polyoxetanes is presented as well as characterization and use in drug delivery. A series of hyperbranched polyoxetanes with multiple PEG arms were synthesized via a one-pot cationic ring-opening polymerization of 3-ethyl-3-hydroxymethyloxetane (EHMO) and its PEGylated derivative (EPMO), in which the feed mass ratio of EHMO to EPMO was 98:2, 96:4, 74:26, or 17:83. Characterization methods included NMR, DLS, FT-IR…
A facile method for synthesis of polyethylene glycol (PEG)-armed hyperbranched polyoxetanes is presented as well as characterization and use in drug delivery. A series of hyperbranched polyoxetanes with multiple PEG arms were synthesized via a one-pot cationic ring-opening polymerization of 3-ethyl-3-hydroxymethyloxetane (EHMO) and its PEGylated derivative (EPMO), in which the feed mass ratio of EHMO to EPMO was 98:2, 96:4, 74:26, or 17:83. Characterization methods included NMR, DLS, FT-IR, DSC, and SEM. Toxicity of the synthesized polymers to human dermal fibroblasts was evaluated using the MTT assay. Formulation into particles was carried out to encapsulate the anticancer drug camptothecin using the single oil-in-water (o/w) solvent evaporation method. The resulting drug encapsulated particles were evaluated for antitumor activity using HN12 cells.
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Organizations
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American Association for Cancer Research (AACR)
Associate member
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Pharmacology and Toxicology Organization (PTSO)
Secretary
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Pharmacology and Toxicology Organization (PTSO)
SGA representative
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5 years at Amgen! 5 years of being a part of an amazing team. Go Path Lab!
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Amazing news! Thank you to all the patients and families who participated in the tarlatamab clinical studies. Together with our dedicated Amgen team,…
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BREAKING: The #FDA granted accelerated approval to tarlatamab for the treatment of patients with #SCLC that has progressed on or after platinum-based…
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