“Laura can be described as nothing short of vibrant. She's passionate, witty, extremely outgoing yet reflective, and wholeheartedly invested in making a difference in all things she is a part of. She's a sharp business woman with a drive for life balance a desire to explore. She's an educator and a leader, with stellar design and marketing ideas and an incredible ability to follow through. She's all about teamwork, collaboration, storytelling, and connection, and does this beautifully, both on and offline. Her 23K+ Instagram followers adore her, as she makes wilderness relevant and desirable to the masses. Offline, I can attest to her spirit and charm. With her entrepreneurial mindset, tech background, and passion for the outdoors, she's poised herself for making waves in this world. This smart, savvy, adorable young lady is going places, no doubt. ”
Laura Lisowski
Seattle, Washington, United States
6K followers
500+ connections
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Endothelial-cardiomyocyte interactions in cardiac development and repair
Harvard Medical School, Annual Review of Physiology
Communication between endothelial cells and cardiomyocytes regulates not only early cardiac
development but also adult cardiomyocyte function, including the contractile state. In the normal
mammalian myocardium, each cardiomyocyte is surrounded by an intricate network of capillaries
and is next to endothelial cells. Cardiomyocytes depend on endothelial cells not only for oxygenated
blood supply but also for local protective signals that promote cardiomyocyte organization…Communication between endothelial cells and cardiomyocytes regulates not only early cardiac
development but also adult cardiomyocyte function, including the contractile state. In the normal
mammalian myocardium, each cardiomyocyte is surrounded by an intricate network of capillaries
and is next to endothelial cells. Cardiomyocytes depend on endothelial cells not only for oxygenated
blood supply but also for local protective signals that promote cardiomyocyte organization and
survival. While endothelial cells direct cardiomyocytes, cardiomyocytes reciprocally secrete factors
that impact endothelial cell function. Understanding how endothelial cells communicate with
cardiomyocytes will be critical for cardiac regeneration, in which the ultimate goal is not simply to
improve systolic function transiently but to establish new myocardium that is both structurally and
functionally normal in the long term.Other authors
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