Luca Monfregola

Luca Monfregola

San Diego, California, United States
393 followers 387 connections

About

Experienced scientist, oligonucleotides and peptides specialist. Creative technology…

Activity

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Experience

  • Johnson & Johnson Innovative Medicine Graphic

    Johnson & Johnson Innovative Medicine

    San Diego, California, United States

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    San Diego, California, United States

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    Carlsbad, California, United States

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    Greater San Diego Area

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    San Diego, California

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    12635 E. Montview Blvd., Aurora, CO, 80045, United States

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Education

  • University of Naples Federico II

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    Thesis entitled: Agonist and antagonist peptide ligands of CXCR4 receptor as marker for the anticancer drugs or diagnostic agents delivery

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    Thesis entitled: “Synthesis of new glycolconjugated of 4 alkyliden-β-lactams”

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    Thesis entitled: “New oxidation strategies of estradiol and correlated compounds”

Publications

  • Chemical Modifications of Peptide Sequences via S Alkylation Reaction.

    Organic Letters

    Other authors
  • Fluorescence study for selecting specific ligands toward HER2 receptor: An example of receptor fragment approach

    European Journal of Medicinal Chemistry

    Other authors
  • Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases

    PLoS ONE

    Other authors
  • Synthetic strategy to prepare dota-based bifunctional chelating agent ready to bind biomolecular probes

    International Journal of Peptide Research and Therapeutics

    Other authors
  • Postsynthetic modification of peptides via chemoselective N-alkylation of their side chains.

    Org Lett.

    Other authors
  • Synthetic strategy for side chain mono-N-alkylation of Fmoc-amino acids promoted by molecular sieves.

    Amino Acids

    Other authors
    • Stefania De Luca
  • Chemical modification of pectin: environmental friendly process for new potential material development

    Polymer Chemistry

    Other authors
  • Physical and water sorption properties of chemically modified pectin with an environmentally friendly process.

    Biomacromolecules

    Other authors
  • A SPR strategy for high-throughput ligand screenings based on synthetic peptides mimicking a selected subdomain of the target protein: a proof of concept on HER2 receptor.

    Bioorg Med Chem.

    Other authors
    • Rosa Maria Vitale
    • Amodeo Pietro
    • Stefania De Luca

Languages

  • Italian

    Native or bilingual proficiency

  • English

    Full professional proficiency

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