About
Passionate Biomedical Scientist. PhD-level with 10+ years of research experience in Cell…
Articles by Naama
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Post Purim Celebration with Bioabroad Houston
Post Purim Celebration with Bioabroad Houston
By Naama Toledano Furman
Activity
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The Hebrew version precedes the English one. מברכים את פרופ' Marcelle Machluf, על שנבחרה לכהן כחברה ב The Council for Higher Education (CHE) -…
The Hebrew version precedes the English one. מברכים את פרופ' Marcelle Machluf, על שנבחרה לכהן כחברה ב The Council for Higher Education (CHE) -…
Liked by Naama Toledano Furman
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Congratulations to Rosalind Bioculture, the 2024 winner of the Tel Aviv University - Coller School of Management x Coller Startup Competition…
Congratulations to Rosalind Bioculture, the 2024 winner of the Tel Aviv University - Coller School of Management x Coller Startup Competition…
Liked by Naama Toledano Furman
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מיכל אמרה בבית החולים שמשהו לא בסדר. אמרו לה שהיא היסטרית, שהיא תופסת מקום של יולדת אחרת ושתלך הביתה. שעה אחר כך היא החלה לפרכס. היה לה אלח דם, והיא…
מיכל אמרה בבית החולים שמשהו לא בסדר. אמרו לה שהיא היסטרית, שהיא תופסת מקום של יולדת אחרת ושתלך הביתה. שעה אחר כך היא החלה לפרכס. היה לה אלח דם, והיא…
Liked by Naama Toledano Furman
Experience
Education
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The Technion
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Volunteer Experience
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Regional manager
ScienceAbroad
- 2 years
Science and Technology
Publications
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The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery.
Nanomedicine (Lond).
In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream where they circulate until they reach the target tissue. The ligand on the NP surface recognizes its specific receptor expressed on the target tissue and the drug is released in a controlled manner. However, once injected in a physiological environment, NPs interact with biological components and are surrounded by a protein corona (PC). This can trigger an immune response and affect NP toxicity and targeting…
In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream where they circulate until they reach the target tissue. The ligand on the NP surface recognizes its specific receptor expressed on the target tissue and the drug is released in a controlled manner. However, once injected in a physiological environment, NPs interact with biological components and are surrounded by a protein corona (PC). This can trigger an immune response and affect NP toxicity and targeting capabilities. In this review, we provide a survey of recent findings on the NP-PC interactions and discuss how the PC can be used to modulate both cytotoxicity and the immune response as well as to improve the efficacy of targeted delivery of nanocarriers.
Other authors -
Reconstructed Stem Cell Nanoghosts: A Natural Tumor Targeting Platform
Nano Letters
The ultimate goal in cancer therapy is achieving selective targeting of cancer cells. We report a novel delivery platform, based on nanoghosts (NGs) produced from the membranes of mesenchymal stem cells (MSCs). Encompassing MSC surface molecules, the MSC-NGs retained MSC-specific in vitro and in vivo tumor targeting capabilities and were cleared from blood-filtering organs. MSC-NGs were found to be biocompatible. Systemic administration of drug loaded MSC-NGs demonstrated 80% inhibition of…
The ultimate goal in cancer therapy is achieving selective targeting of cancer cells. We report a novel delivery platform, based on nanoghosts (NGs) produced from the membranes of mesenchymal stem cells (MSCs). Encompassing MSC surface molecules, the MSC-NGs retained MSC-specific in vitro and in vivo tumor targeting capabilities and were cleared from blood-filtering organs. MSC-NGs were found to be biocompatible. Systemic administration of drug loaded MSC-NGs demonstrated 80% inhibition of human prostate cancer.
Other authors
Languages
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English, Old (ca.450-1100)
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